Results 191 to 200 of about 378,972 (313)

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Development of a childhood food and nutrition security observatory: experience of an interinstitutional initiative in the state of São Paulo. [PDF]

J Pediatr (Rio J)
Viani K, Sakurada M, Costa A, Fisberg M, Maximino P, Cutait R, Committee of Experts – Childhood FNS Observatory.   +6 more
europepmc   +1 more source

Estado de Bienestar y Voluntariado Social

Papeles de Geografí­a, 1996
La expansión del Estado de Bienestar en nuestra sociedad ha supuesto una aproximación a una sociedad más justa, pero en modo alguno ha superado las desigualdades. La participación de los agentes sociales asumiendo compromisos que impliquen a todos los sectores de la sociedad, mejoraría la justicia social y la práctica de la democracia. En esta sociedad
openaire   +2 more sources

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

[Effect of Vimala infant massage on mothers with postpartum depression]. [PDF]

Rev Med Inst Mex Seguro Soc
González AP, Reyes-Méndez MA, Paque-Bautista C, Rodríguez-Ramírez FJ, Sosa-Bustamante GP.   +4 more
europepmc   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

El fenómeno Milei, ¿Qué implica para el Estado Social de Derecho?

Distintos sectores de la sociedad han celebrado que Javier Milei haya llegado a la segunda vuelta presidencial en Argentina, pues él encarna el crecimiento del sector político de los “Libertarios” y sus ideales.
Castro, Mario, Duarte, Saenz Nelson, Hernández, Héctor   +2 more
core  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Do Psychosocial Resources Mitigate the Impact of Adverse Childhood Experiences in Oral Health-Related Quality of Life Among Adolescents. [PDF]

Int J Paediatr Dent
Noronha-Ramos TG, Knorst JK, Ardenghi TM, Emmanuelli B, Brondani B, Tomazoni F.   +5 more
europepmc   +1 more source

Estado Social Real

, 2018
openaire   +3 more sources