Results 211 to 220 of about 45,405 (265)

Work and politics in the era of liquid modernity: meanings attributed by female nurses. [PDF]

Rev Esc Enferm USP
Dias MO, Prata JA, Queiroz ABA, Costa CCPD, Soares SSS, Santos LRO, Lima LDSC, Souza NVD.   +7 more
europepmc   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

["There are no slots, unless you know someone": perception of access to health services by Congolese women residing in Rio de Janeiro, Brazil]. [PDF]

Cad Saude Publica
Colodetti P, Ortega F.
europepmc   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Effect of Using the Food Quotient as a Proxy of the Respiratory Quotient in the Calculation of Energy Expenditure by the Doubly Labeled Water Method in Older Adults. [PDF]

Am J Hum Biol
de Mello DGA, Dos Anjos LA, Ravelli MN, Ferriolli E, Pfrimer K.   +4 more
europepmc   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

Video game use, lifestyle and its association with becoming overweight or obese in Mexican adolescents. [PDF]

PeerJ
Islas Mendoza Y, Vargas Hernandez F, Bermudez Zapata DA, Saucedo Martínez MG, García Cortes LR, Villar Aguirre E, Tamayo Calderón JA, Jiménez Jalpa O, García Cortés E, Camarillo Nava VM, Jimenez Hernandez S, Pérez Camargo DA, Enríquez Estrada VM, Palacios Torres F.   +13 more
europepmc   +1 more source

[Health and nutrition educational intervention during the COVID-19 pandemic: Evolution of nutritional and food security indicators in Mexican women]. [PDF]

Aten Primaria
Monroy-Torres R, Medina Jiménez AK, Castillo Chávez ÁM.   +2 more
europepmc   +1 more source

¿Crisis del Estado Social?

, 2015
openaire   +3 more sources