Results 161 to 170 of about 269,608 (328)

Sintomatologia ansiosa e depressiva no prestador informal de cuidados a doentes oncológicos em estado terminal

, 2011
A vivência de uma doença ameaçadora de vida, como é exemplo o cancro, é reconhecida como uma situação geradora de desadaptação não apenas para o doente mas também para os seus cuidadores, que partilham com ele o sofrimento e o distress psicológico associado (Kissane, Bloch, Burns, McKenzie e Posterino, 1994). Outro dos factores que pode ser considerado
Moutinho, S., Lima, Ligia
openaire   +1 more source

Uma Análise Prospectiva dos Efeitos da Implantação do Complexo Intermodal da Ferronorte ao Município de Rondonópolis-MT

Revista de Estudos Sociais, 2015
O presente artigo visa avaliar os impactos da implantação do terminal intermodal da Ferronorte que liga Santa Fé do Sul, em São Paulo a Rondonópolis, no sudeste de Mato Grosso.
Luís Otávio Bau Macedo, Renato Nataniel Wasques, Roselaine Bonfim de Almeida, Claudia Regina Heck   +3 more
doaj  

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Operativa de buque en las terminales marítimas de contenedores: estado del arte [PDF]

Arango Pastrana Carlos, Cortes Achedad Pablo, Fernández Valverde Joaquín   +2 more
openalex   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Hipertensão pulmonar em pacientes com doença renal crônica terminal internados em um hospital de referência em nefrologia do estado do Pará, Brasil [PDF]

, 2018
Hivis da Costa Sousa, JOELSON FELIPE DA SILVA DE OLIVEIRA, Brenda Brandão Moreira, Esdras Edgar Batista Pereira, José Tadeu Colares Monteiro   +4 more
openalex   +1 more source

Miasis facial asociada con carcinoma espinocelular en estado terminal Facial myiasis associated with end-stage spinocellular carcinoma

Revista Cubana de Estomatología, 2005
La miasis son infestaciones de vertebrados vivos por larvas de moscas que se nutren como parásitos. Frecuentemente, la miasis está relacionada con la pobreza extrema y la falta de higiene en países en desarrollo con climas calientes y húmedos. En esas circunstancias especificas, heridas abiertas y no tratadas, úlceras, tejidos necróticos y todos los ...
Marconi Eduardo Sousa Maciel-Santos, Carlos Alberto Medeiros Martins, Cláudia Marcela Hernández Cancino, Joaquim Celestino da Silva Neto   +3 more
openaire   +1 more source

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

FEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source