Results 171 to 180 of about 595,772 (318)

Intermittent oxygenation during peak fermentation: Effect on fermentation kinetics, volatile composition, and sensory properties. [PDF]

Curr Res Food Sci
Cui D, Cao Y, Huang Y, Yang W, Duan C, Ling M, Lan Y.   +6 more
europepmc   +1 more source

Perivascular Matrix Densification Dysregulates Angiogenesis and Activates Pro‐Inflammatory Endothelial Cells

Advanced Science, EarlyView.
Perivascular matrix densification promotes the emergence of aberrant endothelial tip cells (ATECs) that invade and persist within fibrotic microenvironments. Using in vivo lineage tracing and a human microvessel model, this study shows that fibrous matrix cues destabilize VE‐cadherin–mediated junctions to gate TGF‐β signaling, inducing a pro ...
Jingyi Xia, William Y. Wang, Kyle A. Jacobs, Kairav Maniar, Daphne Lin, Evan H. Jarman, Daniel L. Matera, Kristen Loesel, Christopher D. Davidson, Harrison L. Hiraki, Xiaotian Tan, Eve H. Shikanov, Robert N. Kent, Carole Parent, Xudong Fan, Ariella Shikanov, Matthew L. Kutys, Brendon M. Baker   +17 more
wiley   +1 more source

Functionalized Cytisine Squaramides: Synthesis, Structural Elucidation, and Co-Crystallization. [PDF]

Molecules
Przybył AK, Mintianska A, Huczyński A, Janczak J.   +3 more
europepmc   +1 more source

Natural Products Inspired Scaffold Diversification Leads to Unnatural Molecular Warhead and Covalent Strategy to Modulating Protein Function through Electrophilic Bromine Transfer

Advanced Science, EarlyView.
We report a new thiolate‐reactive α,α‐gem‐dibromo lactam warhead that activates transcription factor Nrf2 and demonstrates anti‐inflammatory activities, which have implications in cancer, neurodegeneration, and cardiovascular diseases. RNA‐seq illuminated detailed transcriptional profiles, and chemical reactions with cysteine‐containing compounds ...
Beau R. Brummel, Sofia Kokkaliari, Qiwen Gao, Jinjing Chen, Larissa Costa de Almeida, Srinivasarao Tenneti, Derek A. Leas, Eli Levit, Lewis S. Alexander, Khalil A. Abboud, Pingrong Wei, Michael D. Cameron, James R. Rocca, Ranjala Ratnayake, Donna D. Zhang, Hendrik Luesch, Robert W. Huigens III   +16 more
wiley   +1 more source

Amidation of Quinolin-2-yl Esters: Base‑, Catalyst‑, Metal‑, and Solvent-Free Conditions. [PDF]

ACS Omega
Talati K, Rajendran S.
europepmc   +1 more source

Gut Mycobiota‐Associated Tryptophan Catabolites Protect Against Metabolic Dysfunction‐Associated Steatotic Liver Disease

Advanced Science, EarlyView.
ABSTRACT Accumulating evidence suggests that the intestinal microbiota participates in the progression of metabolic dysfunction‐associated steatotic liver disease (MASLD) through microbiota‐host interaction. However, the beneficial role of commensal mycobiota in MASLD progression remains poorly understood.
Shuping Qiao, Shuangya Fan, Juan Xu, Zhen Xu, Chen Peng, Junxing Qu, Ziqian Bing, Shizhen Zhou, Sunan Shen, Guifang Xu, Yue Zhao, Tingting Wang   +11 more
wiley   +1 more source

Iodine-catalyzed green and efficient synthesis of secondary and <i>tert</i>-esters of <i>N</i>-acetyl-protected amino acids. [PDF]

RSC Adv
Abbasi GR, Arfan M, Ehsan MF, Rehman A, Shakir I, Latif M.   +5 more
europepmc   +1 more source

Apprendere l’uso dei «lodati scrittori». Autorità ed esempi letterari nelle prose linguistiche di Benedetto Varchi

, 2022
pietrobon ester
core  

Waschti und Ester : Frauenverachtung und Judenfeindschaft widerstehen

Im Buch Ester kommen Themen zur Sprache, die bis heute nichts an Aktualität verloren haben: Frauenverachtung und sexualisierte Gewalt, Machtmissbrauch und Feindschaft gegenüber Jüdinnen und Juden – bis hin zur staatlich organisierten Vernichtung der ...
Bieberstein, Sabine
core  

Functional Analysis of Ligand‐Gated Chloride Channels in a Cnidarian Sheds Light on the Evolution of Inhibitory Signaling

Advanced Science, EarlyView.
We uncover a large variety of putative inhibitory ligand‐gated ion channels (LGICs) in the phylum Cnidaria, the sister group to all bilaterian animals. Phylogenetic analysis suggests a complex evolutionary history of inhibitory LGICs with diverse neurotransmitter ligands.
Abhilasha Ojha, Linda Kloss, Juan D. Montenegro, Simone Albani, Audrey Ortega‐Ramírez, Mihaela Raycheva, Sylvia Joussen, Sabrina Kaul, Michèle Bachmann, Lisa Huf, Günther Schmalzing, Alison G. Cole, Ulrich Technau, Stefan Gründer   +13 more
wiley   +1 more source