Results 221 to 230 of about 192,226 (349)

Tunable and self-reporting esterase-activated cyanide prodrugs exert cytoprotective effects. [PDF]

open access: yesNat Commun
Tong X   +8 more
europepmc   +1 more source

Biocatalytic synthesis of S‐adenosyl‐l‐methionine analogues for allosteric activation of cystathionine‐β‐synthase

open access: yesThe FEBS Journal, EarlyView.
Cystathionine‐β‐synthase (CBS) helps remove harmful homocysteine and supports the production of protective sulfur‐containing molecules. Using its natural activator, S‐adenosyl‐l‐methionine, as a template, we designed and tested 15 analogues. Three activated and stabilized the enzyme, including the newly identified S‐2‐amino‐adenosyl‐l‐methionine. These
Dalibor Nakládal   +18 more
wiley   +1 more source

Benign by design: A paradigm shift in cosmetic ingredient development

open access: yesInternational Journal of Cosmetic Science, EarlyView.
Benign by design strategies enable the creation of biodegradable cosmetic ingredients, reducing environmental persistence while maintaining the intended biological activity. This work compiles design rules and tools to guide the development of more sustainable molecules for the cosmetics industry.
Sandra Mota   +3 more
wiley   +1 more source

Do We Really Know How to Manage Anticoagulated Patients for Periodontal Nonsurgical Therapy? An Observational Cohort Study

open access: yesInternational Journal of Dental Hygiene, EarlyView.
ABSTRACT Objectives The aim of this work is to assess and compare the impact of direct oral anticoagulants (DOACs) versus vitamin K antagonists (VKA) during and immediately after periodontal nonsurgical therapy. Materials and Methods A prospective observational cohort study was conducted with patients who presented a history of cardiovascular disease ...
F. Berton   +5 more
wiley   +1 more source

Characterization of a Feruloyl Esterase from Lactobacillus plantarum

open access: yesApplied and Environmental Microbiology, 2013
M. Esteban-Torres   +4 more
semanticscholar   +1 more source

Diagnostic model based on machine learning with multi‐feature analysis for diabetic peripheral neuropathy in type 2 diabetes: A single‐center retrospective study

open access: yesJournal of Diabetes Investigation, EarlyView.
ABSTRACT Objective Diabetic peripheral neuropathy (DPN) is a common and serious complication of diabetes, which imposes a significant economic burden on both society and individuals. Therefore, early identification and diagnosis are crucial for the prevention and treatment of DPN.
Xi Zheng   +4 more
wiley   +1 more source

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