Results 221 to 230 of about 320,740 (318)

Development of Membrane Transport-Inspired Biomimetic System to Degrade Plasticizers. [PDF]

Chem Asian J
Mandal R, Sar S, Maiti T, Hazra B, Prasad M, Biswas S, Tarafdar PK.   +6 more
europepmc   +1 more source

Single‐Dose TACE‐Like Injection of Sustained‐Release Panobinostat/IL‐12 Polymeric Microparticles is Effective in Preclinical Liver Cancer Models

Advanced Science, EarlyView.
A novel PLGA/PBAE polymer microparticle platform revolutionizes intermediate‐stage liver cancer treatment by co‐delivering panobinostat and IL‐12 via a single TACE‐like injection. This sustained‐release system overcomes tumor immunosuppression, triggers robust innate and adaptive immune responses, and establishes tertiary lymphoid structures ...
Hongzhe Yu, Ling Li, Sachin S. Surwase, Xin Ming M. Zhou, Hongtao Qian, Joel C. Sunshine, Florin M. Selaru, Jordan J. Green   +7 more
wiley   +1 more source

Advances in Cider Flavor: Integrating Apple Raw Materials, Microbial Ecology, and Process Control. [PDF]

Microorganisms
Zhang Z, Yan C, Li J, Zhao L, Li L, Cai R, Wei W, Lu S.   +7 more
europepmc   +1 more source

Enantioselective Access to Trifluoromethylated Spirocyclopropyl Heterocycles

Advanced Science, EarlyView.
We report a rhodium‐catalyzed asymmetric [2+1] spirocyclopropanation of methylene azacycles with trifluoromethyl carbenes in situ derived from fluoroalkyl triftosylhydrazones. ABSTRACT Chiral spirocyclopropyl heterocycles have emerged as privileged three‐dimensional structural motifs in medicinal chemistry.
Yuanhao Zhu, Youzhi Xu, Weitao Zhang, Yongyue Ning, Yaojia Jiang, Yongquan Ning, Genping Huang, Jiawei Cheng, Paramasivam Sivaguru, Xihe Bi   +9 more
wiley   +1 more source

Regional and Vintage-Associated Differences in Commercial Chardonnay Wines from the Shandong Peninsula and the Chugoku Region: Physicochemical, Volatile, and Sensory Profiles with Exploratory Associations with Growing-Season Climate. [PDF]

Foods
Yang D, Yang Y, Li R, Tang X, Zhong K, Murata Y, Fukuda F, Li Z, Sun Y.   +8 more
europepmc   +1 more source

ROS‐Responsive Eye Drop for Controlled Release of 20‐Deoxyingenol Improves Diabetic Corneal Healing by Activating Macrophage Autophagy and Metabolic Reprogramming

Advanced Science, EarlyView.
Schematic illustration of ROS‐responsive TSPBA‐PVA microspheres loaded with 20‐deoxyingenol (TP/20‐DOI) for diabetic corneal wound healing: (a) fabrication and ROS‐triggered release; (b) autophagy activation and metabolic reprogramming in macrophages; (c) suppression of macrophage‐derived CXCL3/CXCL5, attenuation of neutrophil infiltration, and ...
Jiaxin Wu, Wanying Chen, Haijiang Qiu, Weihan Zheng, Ying Jiao, Jingheng Du, Zhudan Zhuang, Xing Hua, Jingyi Gu, Yuheng Liu, Zhaojin Li, Jingbin Xie, Hanxiao Sun, Huifei Lan, Xin Sun, Yunxia Xue, Ting Fu, Zhijie Li, Guobing Chen, Shiyu Li, Jun Liu   +20 more
wiley   +1 more source

Electrochemical oxidative amidation of alcohols towards <i>N</i>-acyl azoles as precursors for amides, esters and thioesters.

Org Biomol Chem
Bartels IMA, Witte MD, Minnaard AJ.
europepmc   +1 more source

Highly stereoselective synthesis of complex molecules <i>via</i> coupling of chiral carbamates with chiral boronic acid esters. [PDF]

RSC Adv
Becker MB, Kazmaier U.
europepmc   +1 more source

Overcoming Drug Resistance by Paclitaxel Resistance in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
In the murine triple‐negative breast cancer (TNBC) model, chemotherapy effectively increases tumor neoantigen burden (TNB). Here, the study constructs a liposomal nanovaccine using antigens derived from in vitro chemotherapy‐treated paclitaxel‐resistant TNBC 4T1 cells.
Bo Chen, Yangyi Wang, Tingting Li, Changqing Guo, Zhe Xie, Zhixian Zhang, Xinghua Han, Wei Wang, Jian Wang, Xiaopeng Ma, Yuanzeng Min   +10 more
wiley   +1 more source

3-SF₅-bicyclo[1.1.1]pentyl alcohol: practical synthesis and use as a precursor for 3-SF₅-bicyclo[1.1.1]pentyl ethers (esters). [PDF]

Chem Sci
Ding YM, Li XY, Shou JY, Zhao X, Zhu XY, Qing FL.   +5 more
europepmc   +1 more source