Helper and ionizable lipids play a crucial role in determining ApoE binding and subsequent liver tropism and LDLR‐mediated uptake. Ionizable lipids primarily govern the LDLR‐independent uptake pathway. This complementary interplay between lipid components ultimately governs LNP delivery performance and therapeutic efficacy in the liver.
Ashish Sarode +16 more
wiley +1 more source
Identification of Volatile Organic Compounds as Natural Antifungal Agents Against <i>Botrytis cinerea</i> in Grape-Based Systems. [PDF]
Martelanc M +4 more
europepmc +1 more source
A novel immunotherapeutic strategy combines injectable, adjuvant‐loaded hydrogels with externally controlled histotripsy to create immune‐priming sites within tumors. This approach generates millimeter‐sized immune‐activated lesions with flexible, patient‐tailored treatment scheduling, enabling precise immune activation through tumor ablation‐mediated ...
Sung Hoon Kim +9 more
wiley +1 more source
Flavouring Group Evaluation 87, Revision 3 (FGE.87Rev3): Consideration of bicyclic secondary alcohols, ketones and related esters evaluated by JECFA (63rd meeting) structurally related to bicyclic secondary alcohols, ketones and related esters evaluated in FGE.47Rev1. [PDF]
EFSA Panel on Food Additives and Flavourings (FAF) +21 more
europepmc +1 more source
Sustainable Structural Hot‐Melt Adhesives Enabled by Functionalized Crystalline Lamellae
A high‐performance, recyclable hot‐melt adhesive is developed from renewable materials. It features functional crystalline lamellae that enhance shear strength and enable closed‐loop recycling. The adhesive also provides excellent water and oxygen barrier properties, meeting both sustainability and performance demands for advanced bonding and sealing ...
Zhitao Hu +7 more
wiley +1 more source
Changes in Resveratrol Containing Phytosterol Liposomes During Model Heating. [PDF]
Igielska-Kalwat J +5 more
europepmc +1 more source
2D MOF with Intrinsic Porosity for Colorimetric Volatile Organic Compounds (VOCs) Detection
An uncommon 2D MOF with intrinsic in‐plane porosity that can be mechanically exfoliated undergoes a distinct and reversible colour change upon exposure to various volatile organic compounds. ABSTRACT In this work, we report an uncommon 2D metal–organic framework (MOF) with intrinsic in‐plane porosity that undergoes a distinct and reversible colour ...
Sergio R. Gamarra +4 more
wiley +1 more source
A Comprehensive Review of Non-Conventional Yeasts: Innovation in Craft Beer Production. [PDF]
Canonico L +3 more
europepmc +1 more source
Impact of Alcohol Content on Alcohol-Ester Interactions in Qingxiangxing Baijiu Through Threshold Analysis. [PDF]
Zhang H +8 more
europepmc +1 more source

