Results 61 to 70 of about 393,838 (308)

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Methods to Improve Joint Genetic Evaluation of Canine Hip Dysplasia Across BVA/KC and FCI Screening Schemes

open access: yesFrontiers in Veterinary Science, 2020
The BVA/KC (British Veterinary Association/Kennel Club) and FCI (Fédération Cynologique Internationale) are the main screening schemes used to evaluate the status of canine hip dysplasia (HD) in Europe.
Shizhi Wang   +4 more
doaj   +1 more source

Age and sex-selective predation moderate the overall impact of predators [PDF]

open access: yes, 2014
© 2014 The Authors. Journal of Animal Ecology published by John Wiley & Sons Ltd on behalf of British Ecological Society. Acknowledgements: Thanks to J. Reid, S. Redpath, A.
Davison, Martin   +6 more
core   +5 more sources

Tumor mutational burden as a determinant of metastatic dissemination patterns

open access: yesMolecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal   +4 more
wiley   +1 more source

Study of QTL Effects Distribution on Accuracy of Genomic Breeding values Estimated Using Bayesian Method

open access: yesپژوهشهای علوم دامی ایران, 2016
Introduction Genetic evaluation and estimation of breeding value are one of the most fundamental elements of breeding programmes for genetic improvement. Recently, genomic selection has become an efficient method to approach this aim.
nazanin mahmoudi   +3 more
doaj  

The Accuracy and Bias of Single-Step Genomic Prediction for Populations Under Selection

open access: yesG3: Genes, Genomes, Genetics, 2017
In single-step analyses, missing genotypes are explicitly or implicitly imputed, and this requires centering the observed genotypes using the means of the unselected founders.
Wan-Ling Hsu   +2 more
doaj   +1 more source

Vision of breeding for organic agriculture [PDF]

open access: yes, 2003
This report describes the results of research into the vision of breeding systems within organic agriculture in the Netherlands. The purpose of the research was to arrive at a vision for breeding in organic agriculture by means of interviews and ...
Baars, Ton   +4 more
core  

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

open access: yesMolecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Accuracy of genomic selection in a rice synthetic population developed for recurrent selection. [PDF]

open access: yes, 2013
Genomic selection is a promising breeding strategy for rapid improvement of complex traits. We investigated the accuracy of genomic estimate breeding values (GEBV) through cross validation in a synthetic population (SP) of broad genetic diversity ...
Ahmadi, Nourollah   +5 more
core  

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

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