Results 51 to 60 of about 7,593,218 (207)

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Capital and income breeding : the role of food supply [PDF]

, 2014
This work was funded by the Natural Environment Research Council (grant number 2003/00616). A. I. Houston and J. M. McNamara were supported by Leverhulme Trust fellowships; A. I.
Stephens, P.A., Boyd, I.L., Stephens, Philip, McNamara, John M., Boyd, Ian L., Harding, Karin C., Harding, Karin C.,, McNamara, John, Stephens, Philip A., Boyd, Ian, Houston, Alasdair I., Houston, A.I., Houston, Alasdair, Harding, K.C., McNamara, J.M.   +14 more
core   +1 more source

Study of QTL Effects Distribution on Accuracy of Genomic Breeding values Estimated Using Bayesian Method

پژوهشهای علوم دامی ایران, 2016
Introduction Genetic evaluation and estimation of breeding value are one of the most fundamental elements of breeding programmes for genetic improvement. Recently, genomic selection has become an efficient method to approach this aim.
nazanin mahmoudi, Ahmad Ayatollahi Mehrgardi, Mahmood Honarvar, Ali Esmailizadeh kashkooeiyeh   +3 more
doaj  

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Prospecting the protein design landscape

FEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona, Katharina T. Stonig, Jens Meiler, Clara T. Schoeder, Monica L. Fernández‐Quintero   +4 more
wiley   +1 more source

Genetic architecture of fresh-market tomato yield

BMC Plant Biology, 2023
Background The fresh-market tomato (Solanum lycopersicum) is bred for direct consumption and is selected for a high yield of large fruits. To understand the genetic variations (distinct types of DNA sequence polymorphism) that influence the yield, we ...
Prashant Bhandari, Juhee Kim, Tong Geon Lee   +2 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Associations between gene polymorphisms, breeding values, and glucose tolerance test parameters in German Holstein sires

Czech Journal of Animal Science, 2018
The association between several gene polymorphisms, the estimated breeding values for milk performance traits, and glucose metabolism measured by the glucose tolerance test (GTT) in German Holstein sires were evaluated.
Jindřich Čítek, Lenka Hanusová, Michaela Brzáková, Libor Večerek, Lothar Panicke, Lucie Lískovcová   +5 more
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Effect of sire type and a by-product based diet on performance and meat quality in growing-finishing pigs

Animal
For many years, pig production has focused on maximizing performance by selecting for maximal muscle growth and feeding diets that allow the animals to express their genetic potential.
E. Kowalski, M. Aluwé, B. Ampe, S. Janssens, N. Buys, S. De Smet, S. Millet   +6 more
doaj   +1 more source