Results 1 to 10 of about 542,878 (302)
Genome position specific priors for genomic prediction [PDF]
BMC Genomics, 2012 Background The accuracy of genomic prediction is highly dependent on the size of the reference population. For small populations, including information from other populations could improve this accuracy.
Brøndum Rasmus +5 more
doaj +5 more sources
Accurate Genomic Prediction Of Human Height [PDF]
Genetics, 2017 We construct genomic predictors for heritable and extremely complex human quantitative traits (height, heel bone density, and educational attainment) using modern methods in high dimensional statistics (i.e., machine learning).
Avery, Steven G. +5 more
core +5 more sources
Ensemble AnalySis with Interpretable Genomic Prediction (EasiGP): Computational tool for interpreting ensembles of genomic prediction models [PDF]
The Plant GenomeAn ensemble of multiple genomic prediction models has grown in popularity due to consistent prediction performance improvements in crop breeding. However, technical tools that analyze the predictive behavior at the genome level are lacking.
Shunichiro Tomura +3 more
doaj +2 more sources
Predicting the accuracy of genomic predictions [PDF]
Genetics Selection Evolution, 2021 Abstract Background Mathematical models are needed for the design of breeding programs using genomic prediction. While deterministic models for selection on pedigree-based estimates of breeding values (PEBV) are available, these have not been fully developed for genomic selection, with a key missing component being the ...
Dekkers, Jack C. M. +2 more
openaire +4 more sources
Genomic Prediction for Twin Pregnancies [PDF]
Animals, 2021 Twinning is a multifactorial trait influenced by both genetic and environmental factors that can negatively impact animal welfare and economic sustainability on commercial dairy operations. To date, using genetic selection as a tool for reducing twinning rates on commercial dairies has been proposed, but not yet implemented.
Shaileen P. McGovern +6 more
openaire +3 more sources
Scientific Reports, 2023 We use UK Biobank and a unique IVF family dataset (including genotyped embryos) to investigate sibling variation in both phenotype and genotype. We compare phenotype (disease status, height, blood biomarkers) and genotype (polygenic scores, polygenic ...
Louis Lello +3 more
doaj +1 more source
Genomics-aided structure prediction [PDF]
Proceedings of the National Academy of Sciences, 2012 We introduce a theoretical framework that exploits the ever-increasing genomic sequence information for protein structure prediction. Structure-based models are modified to incorporate constraints by a large number of non-local contacts estimated from direct coupling analysis (DCA) of co-evolving genomic sequences.
Sulkowska, Joanna I. +4 more
openaire +3 more sources
Genomic prediction using subsampling [PDF]
BMC Bioinformatics, 2017 Genome-wide assisted selection is a critical tool for the genetic improvement of plants and animals. Whole-genome regression models in Bayesian framework represent the main family of prediction methods. Fitting such models with a large number of observations involves a prohibitive computational burden. We propose the use of subsampling bootstrap Markov
Xavier, Alencar +3 more
openaire +2 more sources
Estimation of Pool Construction and Technical Error
Agriculture, 2021 Pooling animals with extreme phenotypes can improve the accuracy of genetic evaluation or provide genetic evaluation for novel traits at relatively low cost by exploiting large amounts of low-cost phenotypic data from animals in the commercial sector ...
John Keele +4 more
doaj +1 more source
Genomic prediction and quantitative trait locus discovery in a cassava training population constructed from multiple breeding stages [PDF]
, 2020 Open Access Article; Published online: 11 Dec 2019Assembly of a training population (TP) is an important component of effective genomic selection‐based breeding programs.
Egesi, C. +11 more
core +1 more source