Results 41 to 50 of about 316,644 (265)

Genomic Prediction and Genetic Correlation of Agronomic, Blackleg Disease, and Seed Quality Traits in Canola (Brassica napus L.)

Plants, 2020
Genomic selection accelerates genetic progress in crop breeding through the prediction of future phenotypes of selection candidates based on only their genomic information.
Mulusew Fikere, Denise M. Barbulescu, M. Michelle Malmberg, Pankaj Maharjan, Phillip A. Salisbury, Surya Kant, Joe Panozzo, Sally Norton, German C. Spangenberg, Noel O. I. Cogan, Hans D. Daetwyler   +10 more
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Genomic predictions in purebreds with a multibreed genomic relationship matrix1 [PDF]

Journal of Animal Science, 2019
AbstractCombining breeds in a multibreed evaluation can have a negative impact on prediction accuracy, especially if single nucleotide polymorphism (SNP) effects differ among breeds. The aim of this study was to evaluate the use of a multibreed genomic relationship matrix (G), where SNP effects are considered to be unique to each breed, that is ...
Yvette, Steyn, Daniela A L, Lourenco, Ignacy, Misztal   +2 more
openaire   +2 more sources

Effect of breed composition in genomic prediction using crossbred pig reference population

Journal of Animal Science and Technology
In contrast to conventional genomic prediction, which typically targets a single breed and circumvents the necessity for population structure adjustments, multi-breed genomic prediction necessitates accounting for population structure to mitigate ...
Euiseo Hong, Yoonji Chung, Phuong Thanh N. Dinh, Yoonsik Kim, Suyeon Maeng, Young jae Choi, Jaeho Lee, Woonyoung Jeong, Hyunji Choi, Seung Hwan Lee   +9 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Asymmetric attrition and secondary chromosome destabilization after double-strand breaks in human embryonic development

Nature Communications
DNA repair in human embryos is poorly understood, and double-strand breaks (DSBs) can cause chromosome loss. We show that chromosomal alterations relative to an induced DSB are asymmetric: acentric arms show complementary gains and losses, while centric ...
Jenna Turocy, Stepan Jerabek, Woonyung Hur, Jimin Kim, Shuangyi Xu, Qiaojin Zhao, Jia Xu, Alex Robles, Xiangyi Liu, Nathan Treff, Diego Marin, Anna-Katerina Hadjantonakis, Dieter Egli   +12 more
doaj   +1 more source

Multivariate GBLUP Improves Accuracy of Genomic Selection for Yield and Fruit Weight in Biparental Populations of Vaccinium macrocarpon Ait

Frontiers in Plant Science, 2018
The development of high-throughput genotyping has made genome-wide association (GWAS) and genomic selection (GS) applications possible for both model and non-model species.
Giovanny Covarrubias-Pazaran, Brandon Schlautman, Luis Diaz-Garcia, Luis Diaz-Garcia, Edward Grygleski, James Polashock, Jennifer Johnson-Cicalese, Nicholi Vorsa, Massimo Iorizzo, Juan Zalapa   +9 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Genomic predictions under different genetic architectures are impacted by mating designs

Veterinary and Animal Science
Mating in animal communities must be managed in a way that assures the performance increase in the progenies without increasing the rate of inbreeding. It has currently become possible to identify millions of single nucleotide polymorphisms (SNPs), and ...
Sahar Ansari, Navid Ghavi Hossein-Zadeh, Abdol Ahad Shadparvar   +2 more
doaj   +1 more source

Multi-environment analysis enhances genomic prediction accuracy of agronomic traits in sesame

Frontiers in Genetics, 2023
Introduction: Sesame is an ancient oilseed crop containing many valuable nutritional components. The demand for sesame seeds and their products has recently increased worldwide, making it necessary to enhance the development of high-yielding cultivars ...
Idan Sabag, Idan Sabag, Ye Bi, Zvi Peleg, Gota Morota   +4 more
doaj   +1 more source