Results 31 to 40 of about 316,644 (265)

Preselecting Variants from Large-Scale Genome-Wide Association Study Meta-Analyses Increases the Genomic Prediction Accuracy of Growth and Carcass Traits in Large White Pigs

Animals, 2023
Preselected variants associated with the trait of interest from genome-wide association studies (GWASs) are available to improve genomic prediction in pigs.
Chen Wei, Chengjie Chang, Wenjing Zhang, Duanyang Ren, Xiaodian Cai, Tianru Zhou, Shaolei Shi, Xibo Wu, Jinglei Si, Xiaolong Yuan, Jiaqi Li, Zhe Zhang   +11 more
doaj   +1 more source

Multi-Trait Multi-Environment Genomic Prediction of Agronomic Traits in Advanced Breeding Lines of Winter Wheat

Frontiers in Plant Science, 2021
Genomic prediction is a promising approach for accelerating the genetic gain of complex traits in wheat breeding. However, increasing the prediction accuracy (PA) of genomic prediction (GP) models remains a challenge in the successful implementation of ...
Harsimardeep S. Gill, Jyotirmoy Halder, Jinfeng Zhang, Navreet K. Brar, Teerath S. Rai, Cody Hall, Amy Bernardo, Paul St Amand, Guihua Bai, Eric Olson, Shaukat Ali, Brent Turnipseed, Sunish K. Sehgal   +12 more
doaj   +1 more source

The Dimensionality of Genomic Information and Its Effect on Genomic Prediction [PDF]

Genetics, 2016
Abstract The genomic relationship matrix (GRM) can be inverted by the algorithm for proven and young (APY) based on recursion on a random subset of animals. While a regular inverse has a cubic cost, the cost of the APY inverse can be close to linear.
Pocrnic, Ivan, Lourenco, Daniela a L, Masuda, Yutaka, Legarra, Andres, Misztal, Ignacy   +4 more
openaire   +5 more sources

Estimation of genomic prediction accuracy from reference populations with varying degrees of relationship. [PDF]

PLoS ONE, 2017
Genomic prediction is emerging in a wide range of fields including animal and plant breeding, risk prediction in human precision medicine and forensic.
S Hong Lee, Sam Clark, Julius H J van der Werf   +2 more
doaj   +1 more source

Accurate Genomic Prediction of Human Height [PDF]

Genetics, 2017
Abstract Hsu et al. used advanced methods from machine learning to analyze almost half a million genomes. They produced, for the first time, accurate genomic predictors for complex traits such as height, bone density, and educational attainment...
Lello, Louis, Avery, Steven G., Tellier, Laurent, Vazquez, Ana I., de los Campos, Gustavo, Hsu, Stephen D. H.   +5 more
openaire   +4 more sources

Comparison of Single-Trait and Multi-Trait GBLUP Models for Genomic Prediction in Red Clover

Agronomy
Red clover (Trifolium pratense) is a perennial forage legume wildly used in temperate regions, including northern Europe. Its breeders are under increasing pressure to obtain rapid genetic gains to meet the high demand for improved forage yield and ...
Johanna Osterman, Lucia Gutiérrez, Linda Öhlund, Rodomiro Ortiz, Cecilia Hammenhag, David Parsons, Mulatu Geleta   +6 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Exploring the genetic architecture and improving genomic prediction accuracy for mastitis and milk production traits in dairy cattle by mapping variants to hepatic transcriptomic regions responsive to intra-mammary infection

Genetics Selection Evolution, 2017
Background A better understanding of the genetic architecture of complex traits can contribute to improve genomic prediction. We hypothesized that genomic variants associated with mastitis and milk production traits in dairy cattle are enriched in ...
Lingzhao Fang, Goutam Sahana, Peipei Ma, Guosheng Su, Ying Yu, Shengli Zhang, Mogens Sandø Lund, Peter Sørensen   +7 more
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Genomic Prediction Using Prior Quantitative Trait Loci Information Reveals a Large Reservoir of Underutilised Blackleg Resistance in Diverse Canola (Brassica napus L.) Lines

The Plant Genome, 2018
Genomic prediction is becoming a popular plant breeding method to predict the genetic merit of lines. While some genomic prediction results have been reported in canola, none have been evaluated for blackleg disease.
Mulusew Fikere, Denise M. Barbulescu, Michelle M. Malmberg, Fan Shi, Joshua C.O. Koh, Anthony T. Slater, Iona M. MacLeod, Phillip J. Bowman, Phillip A. Salisbury, German C. Spangenberg, Noel O.I. Cogan, Hans D. Daetwyler   +11 more
doaj   +1 more source