Results 31 to 40 of about 2,453,732 (306)

Prediction of operons in microbial genomes [PDF]

Nucleic Acids Research, 2001
Operon structure is an important organization feature of bacterial genomes. Many sets of genes occur in the same order on multiple genomes; these conserved gene groupings represent candidate operons. This study describes a computational method to estimate the likelihood that such conserved gene sets form operons.
M D, Ermolaeva, O, White, S L, Salzberg
openaire   +2 more sources

Best Linear Unbiased Prediction of Genomic Breeding Values Using a Trait-Specific Marker-Derived Relationship Matrix [PDF]

, 2010
Background: With the availability of high density whole-genome single nucleotide polymorphism chips, genomic selection has become a promising method to estimate genetic merit with potentially high accuracy for animal, plant and aquaculture species of ...
Bijma, Piter, Bijma Piter, Dirk-Jan de Koning, Liu, J.F., Bijma, P., de Koning Dirk-Jan, Zhang, Zhe, Ding, Xiangdong, Zhang, Qin, Koning, D.J., de, Liu, Jianfeng, Qin Zhang, de Koning, Dirk-Jan, Zhang Qin, Zhe Zhang, Z., Ding, Z., Zhang Zhe, Ding Xiangdong, Piter Bijma, Jianfeng Liu, Xiangdong Ding, Zhe Zhang, Liu Jianfeng   +22 more
core   +1 more source

Increased Accuracy of Genomic Prediction Using Preselected SNPs from GWAS with Imputed Whole-Genome Sequence Data in Pigs

Animals, 2023
Enhancing the accuracy of genomic prediction is a key goal in genomic selection (GS) research. Integrating prior biological information into GS methods using appropriate models can improve prediction accuracy for complex traits.
Yiyi Liu, Yuling Zhang, Fuchen Zhou, Zekai Yao, Yuexin Zhan, Zhenfei Fan, Xianglun Meng, Zebin Zhang, Langqing Liu, Jie Yang, Zhenfang Wu, Gengyuan Cai, Enqin Zheng   +12 more
doaj   +1 more source

Predictive Genomics of Cardioembolic Stroke [PDF]

Stroke, 2009
Cardioembolic stroke is a complex disease resulting from the interaction of numerous factors. Using data from Genes Affecting Stroke Risk and Outcome Study (GASROS), we show that a multivariate predictive model built using Bayesian networks is able to achieve a predictive accuracy of 86% on the fitted values as computed by the area under the receiver ...
Rachel Badovinac, Ramoni, Blanca E, Himes, Michele M, Sale, Karen L, Furie, Marco F, Ramoni   +4 more
openaire   +2 more sources

Pre-selecting markers based on fixation index scores improved the power of genomic evaluations in a combined Yorkshire pig population

Animal, 2020
Combining different swine populations in genomic prediction can be an important tool, leading to an increased accuracy of genomic prediction using single nucleotide polymorphism (SNP) chip data compared with within-population genomic.
S. Ye, H. Song, X. Ding, Z. Zhang, J. Li
doaj   +1 more source

Genomic Prediction of 16 Complex Disease Risks Including Heart Attack, Diabetes, Breast and Prostate Cancer

Scientific Reports, 2019
We construct risk predictors using polygenic scores (PGS) computed from common Single Nucleotide Polymorphisms (SNPs) for a number of complex disease conditions, using L1-penalized regression (also known as LASSO) on case-control data from UK Biobank ...
Louis Lello, Timothy G. Raben, Soke Yuen Yong, Laurent C. A. M. Tellier, Stephen D. H. Hsu   +4 more
doaj   +1 more source

Effects of the number of markers per haplotype and clustering of haplotypes on the accuracy of QTL mapping and prediction of genomic breeding values [PDF]

, 2009
The aim of this paper was to compare the effect of haplotype definition on the precision of QTL-mapping and on the accuracy of predicted genomic breeding values.
Veerkamp Roel F, Theo HE Meuwissen, Egbert F Knol, Addie LJ Vereijken, Calus Mario PL, Vereijken Addie LJ, Knol, E.F., Schrooten, C., Windig, J.J., Meuwissen Theo HE, Knol Egbert F, Calus, M.P.L., Vereijken, A.L.J., Roel F Veerkamp, Jack J Windig, Windig Jack J, Veerkamp, R.F., Chris Schrooten, Schrooten Chris, Meuwissen, T.H.E., Mario PL Calus   +20 more
core   +1 more source

Translating genomics into risk prediction [PDF]

Thorax, 2017
Cigarette smoking is a leading risk factor in the development of cardiovascular, pulmonary and malignant diseases worldwide.1 Yet, it remains one of the most challenging environmental exposures to quantify. Rudimentary categorisations of ‘never’, ‘former’ and ‘current’ smoker capture only a fraction of the complexity associated with the exposure ...
Emily S, Wan, Dawn L, DeMeo
openaire   +2 more sources

Haplotype analysis of genomic prediction by incorporating genomic pathway information based on high-density SNP marker in Chinese yellow-feathered chicken

Poultry Science, 2023
: Genomic selection using single nucleotide polymorphism (SNP) markers is now intensively investigated in breeding and has been widely utilized for genetic improvement.
Haoqiang Ye, Zhenqiang Xu, Semiu Folaniyi Bello, Qianghui Zhu, Shaofen Kong, Ming Zheng, Xiang Fang, Xinzheng Jia, Haiping Xu, Xiquan Zhang, Qinghua Nie   +10 more
doaj   +1 more source

Multi-population genomic prediction using a multi-task Bayesian learning model [PDF]

, 2014
Background Genomic prediction in multiple populations can be viewed as a multi-task learning problem where tasks are to derive prediction equations for each population and multi-task learning property can be improved by sharing information across ...
Li, C., Sargolzaei, M., Schenkel, F., Chen, L.   +3 more
core   +1 more source