Results 51 to 60 of about 1,988,937 (263)

Datasets to test the importance of genetic architecture in marker selection decisions for genomic prediction

open access: yes, 2023
Files include structural variant calls of the maize parental lines, genotypic data for recombinant inbred lines (RILs), simulated trait values for each RIL with different genetic architectures, input data for genomic prediction models with different ...
Hirsch, Candice N   +6 more
core   +1 more source

Accurate Genomic Prediction of Human Height [PDF]

open access: yesGenetics, 2017
Abstract Hsu et al. used advanced methods from machine learning to analyze almost half a million genomes. They produced, for the first time, accurate genomic predictors for complex traits such as height, bone density, and educational attainment...
Lello, Louis   +5 more
openaire   +4 more sources

Multi-population genomic prediction using a multi-task Bayesian learning model [PDF]

open access: yes, 2014
Background Genomic prediction in multiple populations can be viewed as a multi-task learning problem where tasks are to derive prediction equations for each population and multi-task learning property can be improved by sharing information across ...
Li, C.   +3 more
core   +1 more source

Impact of Genotype Imputation on the Performance of GBLUP and Bayesian Methods for Genomic Prediction [PDF]

open access: yes, 2014
The aim of this study was to evaluate the impact of genotype imputation on the performance of the GBLUP and Bayesian methods for genomic prediction. A total of 10,309 Holstein bulls were genotyped on the BovineSNP50 BeadChip (50 k).
Li, C.   +3 more
core   +1 more source

Comparison of Single-Trait and Multi-Trait GBLUP Models for Genomic Prediction in Red Clover

open access: yesAgronomy
Red clover (Trifolium pratense) is a perennial forage legume wildly used in temperate regions, including northern Europe. Its breeders are under increasing pressure to obtain rapid genetic gains to meet the high demand for improved forage yield and ...
Johanna Osterman   +6 more
doaj   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Exploring the genetic architecture and improving genomic prediction accuracy for mastitis and milk production traits in dairy cattle by mapping variants to hepatic transcriptomic regions responsive to intra-mammary infection

open access: yesGenetics Selection Evolution, 2017
Background A better understanding of the genetic architecture of complex traits can contribute to improve genomic prediction. We hypothesized that genomic variants associated with mastitis and milk production traits in dairy cattle are enriched in ...
Lingzhao Fang   +7 more
doaj   +1 more source

Estimation of genomic prediction accuracy from reference populations with varying degrees of relationship. [PDF]

open access: yesPLoS ONE, 2017
Genomic prediction is emerging in a wide range of fields including animal and plant breeding, risk prediction in human precision medicine and forensic.
S Hong Lee   +2 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Genomic predictions in purebreds with a multibreed genomic relationship matrix1 [PDF]

open access: yesJournal of Animal Science, 2019
AbstractCombining breeds in a multibreed evaluation can have a negative impact on prediction accuracy, especially if single nucleotide polymorphism (SNP) effects differ among breeds. The aim of this study was to evaluate the use of a multibreed genomic relationship matrix (G), where SNP effects are considered to be unique to each breed, that is ...
Yvette, Steyn   +2 more
openaire   +2 more sources

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