Results 11 to 20 of about 1,988,937 (263)
Genomic prediction is transforming animal and plant breeding and its utility to predict human disease risk is being explored. The method aims to predict an individual’s future phenotype based on only a DNA test.
Zibei Lin (7869893) +2 more
core +2 more sources
Development of genomic prediction in sorghum
Genomic selection can increase the rate of genetic gain in plant breeding programs by shortening the breeding cycle. Gain can also be increased through higher selection intensities, as the size of the population available for selection can be increased ...
Emma S. Mace +10 more
core +6 more sources
Predicting the accuracy of genomic predictions [PDF]
Abstract Background Mathematical models are needed for the design of breeding programs using genomic prediction. While deterministic models for selection on pedigree-based estimates of breeding values (PEBV) are available, these have not been fully developed for genomic selection, with a key missing component being the ...
Dekkers, Jack C. M. +2 more
openaire +4 more sources
Genomic Prediction for Twin Pregnancies [PDF]
Twinning is a multifactorial trait influenced by both genetic and environmental factors that can negatively impact animal welfare and economic sustainability on commercial dairy operations. To date, using genetic selection as a tool for reducing twinning rates on commercial dairies has been proposed, but not yet implemented.
Shaileen P. McGovern +6 more
openaire +3 more sources
Promoter prediction in the human genome [PDF]
Abstract Computational prediction of eukaryotic polII promoters has been one of the most elusive problems despite considerable effort devoted to the study. Researchers have looked for various types of signals around the transcriptional start site (TSS), viz.
Sridhar Hannenhalli, Samuel Levy
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Genomic prediction using subsampling [PDF]
Genome-wide assisted selection is a critical tool for the genetic improvement of plants and animals. Whole-genome regression models in Bayesian framework represent the main family of prediction methods. Fitting such models with a large number of observations involves a prohibitive computational burden. We propose the use of subsampling bootstrap Markov
Alencar Xavier +3 more
openaire +2 more sources
AGenDA: gene prediction by cross-species sequence comparison [PDF]
Taher L, Rinner O, Garg S, Sczyrba A, Morgenstern B. AGenDA: gene prediction by cross-species sequence comparison. Nucleic Acids Research. 2004;32(Web Server):W305-W308.Automatic gene prediction is one of the major challenges in computational sequence ...
Sczyrba, Alexander ; https://orcid.org/ +9 more
core +1 more source
Best Linear Unbiased Prediction of Genomic Breeding Values Using a Trait-Specific Marker-Derived Relationship Matrix [PDF]
Background: With the availability of high density whole-genome single nucleotide polymorphism chips, genomic selection has become a promising method to estimate genetic merit with potentially high accuracy for animal, plant and aquaculture species of ...
Bijma, Piter +23 more
core +1 more source
Imputation of genotypes from low- to high-density genotyping platforms and implications for genomic selection [PDF]
peer-reviewedThe objective of this study was to quantify the accuracy achievable from imputing genotypes from a commercially available low-density marker panel (2730 single nucleotide polymorphisms (SNPs) following edits) to a commercially available ...
J.F. Kearney +3 more
core +1 more source
Protein structure prediction in genomics [PDF]
As the number of completely sequenced genomes rapidly increases, including now the complete Human Genome sequence, the post-genomic problems of genome-scale protein structure determination and the issue of gene function identification become ever more pressing.
openaire +2 more sources

