Biomarkers of Lupus Nephritis Histopathology: Where Do We Stand?
Arthritis &Rheumatology, Accepted Article.Objective Lupus nephritis (LN) is characterized by a variable disease course, necessitating continuous monitoring. There is an urgent need to identify non‐invasive biomarkers. By reviewing and critically assessing the quality of existing studies on LN biomarkers correlating with histopathology, we here explore the challenges in promoting their use in ...
Valentina Querin +11 more
wiley +1 more source
Serum uric acid as a marker of microvascular damage in systemic sclerosis patients [PDF]
, 2016 Background: Microvascular damage of skin and internal organs is a hallmark of systemic sclerosis (SSc). Serum uric acid (UA) represents a marker of inflammation and endothelial dysfunction.
Amoroso, Antonio +9 more
core +1 more source
Arthritis &Rheumatology, Accepted Article.Background Using hydroxychloroquine (HCQ) dose of 5 mg/kg/day in systemic lupus erythematosus (SLE) is associated with a higher risk of flares; HCQ blood level monitoring could be a better way to adjust HCQ dose. We studied the upper threshold for a reference range of HCQ levels to inform routine monitoring.
Shivani Garg +42 more
wiley +1 more source
Risk prediction to inform surveillance of chronic kidney disease in the US Healthcare Safety Net: a cohort study. [PDF]
, 2016 BackgroundThe capacity of electronic health record (EHR) data to guide targeted surveillance in chronic kidney disease (CKD) is unclear. We sought to leverage EHR data for predicting risk of progressing from CKD to end-stage renal disease (ESRD) to help ...
Chertow, Glenn M +5 more
core +2 more sources
5‐Methylcytosine Analysis of miRNAs in Minimal Change Disease
Biotechnology and Applied Biochemistry, EarlyView.ABSTRACT Minimal change disease (MCD) is a glomerular disorder, which is the most common cause of nephrotic syndrome in children. Additionally, the prevalence of MCD in adults has been increasing in recent years. During protein synthesis, noncoding RNAs can be regulated through a variety of modifications, which helps preserve biological diversity and ...
Huiyi Zeng +14 more
wiley +1 more source
Glomerular filtration rate estimated using creatinine, cystatin
, 2013 GM Lucas +6 more
openalex +1 more source
British Journal of Clinical Pharmacology, EarlyView.Aim Cannabis‐based medicines are gaining interest and being explored for new therapeutic indications, many of which commonly affect older medical patients. As most previous studies of the population pharmacokinetics of cannabinoids have been performed in healthy adults, this study aimed to investigate the population pharmacokinetics of Δ9 ...
Ida Klitzing Storgaard +12 more
wiley +1 more source
Estimated glomerular filtration rate in observational and interventional studies in chronic kidney disease [PDF]
Estimated glomerular filtration rate is considered the principal measure of kidney function and, together with albuminuria, is a relevant prognostic factor for the development of end-stage kidney disease.
Abenavoli C. +8 more
core +1 more source
Use of plasma clearance of inulin for estimating glomerular filtration rate in cats [PDF]
, 1996 Scott A. Brown +2 more
openalex +1 more source
Pharmacokinetics of teicoplanin in paediatric patients—A systematic review of current literature
British Journal of Clinical Pharmacology, EarlyView.Background and Objective Teicoplanin is commonly used in children to treat gram‐positive infections and is sometimes used off‐label prophylactically in surgical or paediatric oncology settings. The pharmacokinetics (PK) of teicoplanin in children exhibit considerable variability, such as in critically ill children or those with renal impairment.
Noa E. Wijnen +4 more
wiley +1 more source