Results 131 to 140 of about 221,285 (352)

Changes of Estimated Glomerular Filtration Rate and Glycated Hemoglobin A1c in Diabetic Macular Edema Patients Treated by Ranibizumab and Aflibercept in the Tertiary Referral Hospital [PDF]

, 2022
Wei-Ning Ku, Peng‐Tai Tien, Chun‐Ju Lin, Chun-Chi Chiang, Ning‐Yi Hsia, Chun‐Ting Lai, Chih‐Hsin Muo, Henry Bair, Huan‐Sheng Chen, Jane‐Ming Lin, Wen-Lu Chen, Yi‐Yu Tsai   +11 more
openalex   +1 more source

Effect of developmental changes on pharmacokinetics of drugs used in the treatment of infant acute lymphoblastic leukaemia—A comprehensive review

British Journal of Clinical Pharmacology, EarlyView.
While the event‐free survival (EFS) of children treated for acute lymphoblastic leukaemia (ALL) has improved greatly in the last decades, the EFS for patients diagnosed with ALL before the age of one is still under 50%. This outcome further decreases when infants have a rearrangement in the gene encoding histone‐lysine N‐methyltransferase 2A (KMT2A ...
Tirsa de Kluis, Leiah J. Brigitha, Lidwien M. Hanff, Alwin D. R. Huitema, Inge M. van der Sluis, Meta H. M. Diekstra   +5 more
wiley   +1 more source

Improvement in Renal Function and Reduction in Serum Uric Acid with Intensive Statin Therapy in Older Patients: A Post Hoc Analysis of the SAGE Trial. [PDF]

, 2015
BackgroundImprovement in renal function and decreases in serum uric acid (SUA) have been reported following prolonged high-intensity statin (HMG-CoA reductase inhibitor) therapy.
Deedwania, Prakash C, Fayyad, Rana S, Laskey, Rachel E, Stone, Peter H, Wilson, Daniel J   +4 more
core  

Variability in estimated glomerular filtration rate and the incidence of type 2 diabetes: a nationwide population-based study [PDF]

, 2020
You‐Bin Lee, Dahye Kim, Eun Roh, So-hyeon Hong, Jung A Kim, Hye Jin Yoo, Sei Hyun Baik, Kyungdo Han, Kyung Mook Choi   +8 more
openalex   +1 more source

Human vs. artificial intelligence: Physicians outperform ChatGPT in real‐world pharmacotherapy counselling

British Journal of Clinical Pharmacology, EarlyView.
Aims To assess the utility of the artificial intelligence (AI) chatbot ChatGPT (openly available version 3.5) in responding to real‐world pharmacotherapeutic queries from healthcare professionals. Methods Three independent and blinded evaluators with different levels of medical expertise and professional experience (beginner, advanced, and expert ...
Benjamin Krichevsky, Stefan Engeli, Stefanie M. Bode‐Böger, Felix Koop, Martin Schulze Westhoff, Sebastian Schröder, Carsten Schumacher, Thorben Pape, Dirk O. Stichtenoth, Johannes Heck   +9 more
wiley   +1 more source

A new equation to estimate the glomerular filtration rate in children, adolescents and young adults [PDF]

, 2013
Liesbeth Hoste, Laurence Dubourg, Luciano da Silva Selistre, V. de Souza, Bruno Ranchin, Aoumeur Hadj‐Aïssa, Pierre Cochat, Frank Martens, Hans Pottel   +8 more
openalex   +1 more source

Calculation of the estimated glomerular filtration rate using the 2021 CKD-EPI creatinine equation and whole blood creatinine values measured with Radiometer ABL 827 FLEX

, 2022
Lu Song, Vincent Buggs, Vishnu Amaram Samara, Shadfar Bahri   +3 more
openalex   +1 more source

Translation of a physiologically‐based pharmacokinetic model for dabigatran etexilate to the design of a safety and efficacy study in post‐partum women

British Journal of Clinical Pharmacology, EarlyView.
Aims To translate a PBPK model developed for the direct oral anticoagulant, dabigatran etexilate, the prodrug of dabigatran, based on data obtained from healthy men to healthy non‐pregnant, pregnant and post‐partum women. To evaluate safety and efficacy of dabigatran etexilate in post‐partum women using simulations and design a future clinical study to
Kayode Ogungbenro, Lorna Aucott, Farhad Kamali, Paul Ayuk   +3 more
wiley   +1 more source

A real‐world data‐driven approach to optimizing enoxaparin dosing in burn patients

British Journal of Clinical Pharmacology, EarlyView.
Aim Enoxaparin dosing in burn patients is challenging due to physiological changes affecting absorption, distribution and clearance. The objectives of this study are to develop a population pharmacokinetic (PK) model for enoxaparin in burn patients, evaluate target attainment with current equation‐based (EQ) dosing and propose an optimized dosing ...
Babajide Shenkoya, Venkata Yellepeddi, Ann Marie B. Prazak, Mathangi Gopalakrishnan   +3 more
wiley   +1 more source

Estimated Glomerular Filtration Rate [PDF]

Anesthesiology, 2013
John G T, Augoustides, Mark D, Neuman, Lee A, Fleisher   +2 more
openaire   +2 more sources