Results 181 to 190 of about 6,936,552 (305)

Genetic overlap between estimated glomerular filtration rate and cardiovascular disease identifies potential targets for cardiorenal syndrome. [PDF]

Ren Fail
Li W, Chen Y, Xiong W, Yuan S.
europepmc   +1 more source

Estimated Glomerular Filtration Rate [PDF]

, 2020
openaire   +1 more source

Model‐based clinical pharmacology profiling of subcutaneous nivolumab in renal cell carcinoma: Bridging to alternative dosing regimens and indications

Clinical Pharmacology &Therapeutics, EarlyView.
A novel model‐informed drug development (MIDD) approach was employed to derive the coprimary endpoints (time‐averaged serum concentration over 28 days [Cavgd28] and minimum serum concentration at steady state [Cminss]) of the phase III CheckMate 67T study (NCT04810078).
Yue Zhao, Zheyi Hu, Elizabeth Gibson, Li Zhu, Heather Vezina, Anna G. Kondic   +5 more
wiley   +1 more source

Sex- and age-specific associations between body composition markers and estimated glomerular filtration rate-results of a population-based study. [PDF]

Clin Kidney J
Günther MA, Ittermann T, Völzke H, Stracke S, Endlich K, Bülow R, Nauck M, Wiese M, Aghdassi A, Markus MRP, von Rheinbaben S.   +10 more
europepmc   +1 more source

New Equations for Estimating Glomerular Filtration Rate

Clinical Chemistry, 2021
Anthony A Killeen, Gary L Horowitz
openaire   +2 more sources

Creatinine–Cystatin C Discrepancy and Renal Transporter Polymorphisms in Japanese Patients with Breast Cancer Receiving Abemaciclib

Clinical Pharmacology &Therapeutics, EarlyView.
Abemaciclib increases serum creatinine by inhibiting renal tubular transporters rather than reducing true glomerular filtration rate, a phenomenon known as pseudo‐acute kidney injury. Creatinine–cystatin C discrepancy and genetic determinants of this elevation remain insufficiently characterized in Japanese patients.
Hiroaki Watanabe, Keita Hirai, Takaaki Oba, Mayu Ono, Ken‐ichi Ito, Takafumi Naito   +5 more
wiley   +1 more source

Incident Hypertension in Young Adults With a Mild Estimated Glomerular Filtration Rate Reduction. [PDF]

J Am Heart Assoc
Ahmed S, Hussain J, Grubic N, Akbari A, Ravani P, Tanuseputro P, Hundemer GL, Ramsay T, Tangri N, Bugeja A, Knoll GA, Maneul D, Sud M, Dhaliwal S, Chanchlani R, Sood MM.   +15 more
europepmc   +1 more source

Limited Value of Cystatin-C over Estimated Glomerular Filtration Rate for Heart Failure Risk Stratification

Background: to compare the prognostic value of estimated glomerular filtration rate, cystatin-C, an alternative renal biomarker, and their combination, in an outpatient population with heart failure.Estimated glomerular filtration rate is routinely used ...
Urrutia de Diego, Agustín, de Antonio Ferrer, Marta, Bayés Genís, Antoni, Zamora, Elisabet, Vila, Joan, Gastelurrutia, Paloma, Lupón, Josep, Galán, Amparo   +7 more
core  

Model‐Informed Dose Optimization of Anakinra in Preterm Neonates Implications for Safe and Effective Dosing

Clinical Pharmacology &Therapeutics, EarlyView.
Anakinra, an interleukin‐1 receptor antagonist, shows promise for reducing inflammatory complications of premature birth. However, the pharmacokinetics (PK) of anakinra in neonates has not been characterized, limiting evidence‐based dosing. This study aimed to develop a population PK model for anakinra to guide dosing in preterm neonates.
Jia Li, David K. Metz, Elys Green, Gergely Toldi, Robert Galinsky, Megan Clark, Rebecka Atkinson, Ina Rudloff, Josephine C. Owen, Sara K. DiSimone, Samuel C. Forster, Steven X. Cho, Atif Majid, Graeme R. Polglase, Marcel Favilla, Pramod Pharande, Atul Malhotra, Calum T. Roberts, Scott H. Stansfield, Arvind Sehgal, Kenneth Tan, Alistair J. Gunn, Philip J. Berger, Alex Veldman, Rod W. Hunt, Claudia A. Nold‐Petry, Marcel F. Nold, Carl M. J. Kirkpatrick   +27 more
wiley   +1 more source

Impact of Estimated Glomerular Filtration Rate Equations on Vancomycin Dosing and Treatment Outcomes. [PDF]

Drug Des Devel Ther
Gu Q, Chen Y, Zhao A, Zhu H, Wang J, Kong M, Chen X, Liu Y, Zhang H, Chen D.   +9 more
europepmc   +1 more source