Results 81 to 90 of about 5,778,717 (303)

Advances in glomerular filtration rate-estimating equations [PDF]

open access: yesCurrent Opinion in Nephrology and Hypertension, 2010
Estimated glomerular filtration rate (eGFR) is now commonly reported by clinical laboratories. Here, we review the performance of current creatinine and cystatin C-based estimating equations as well as demonstration of their utility in public health and clinical practice.Lower levels of GFR are associated with multiple adverse outcomes, including acute
Lesley A, Stevens   +2 more
openaire   +2 more sources

Characteristics of DM1 patients according to estimated glomerular filtration rate.

open access: yes, 2016
Characteristics of DM1 patients according to estimated glomerular filtration rate.
Bruna de Moraes Mazetto (2208958)   +9 more
core   +1 more source

Targeted β‐Glucan‐Veiled Oral Apremilast Nanotherapy Modulates Key Dysbiosis‐Associated Gut Microbiota and Alleviates Ulcerative Colitis‐Associated Anxiety, Depression, and Neuropsychiatric Behaviors

open access: yesAdvanced Science, EarlyView.
This study introduces β‐glucan‐shielded apremilast laden nanomicelles that withstand gastrointestinal degradation, selectively accumulate in inflamed colon tissue, and modulate the microbiota–gut–brain axis. The formulation restores barrier integrity, reduces systemic and neuroinflammation, and improves anxiety‐ and depression‐like behaviors in colitis
Chandrashekhar Jori   +10 more
wiley   +1 more source

The Variability of Estimated Glomerular Filtration Rate Decline in Alport Syndrome

open access: yesCanadian Journal of Kidney Health and Disease, 2016
Background: A progressive trajectory toward renal failure is common in patients with Alport syndrome. Genotype-phenotype correlations have been well described; however, the natural history of the trajectory toward renal failure is not well described ...
David Langsford   +4 more
doaj   +1 more source

The association of coronary artery calcium score with glomerular filtration rate and the influence of sex, age, blood pressure, and cholesterol

open access: yesMedičnì Perspektivi, 2020
Chronic kidney disease puts an individual at a higher risk of all-cause and cardiovascular death. Coronary artery calcium score reflects the accumulation of calcium in the walls of the coronary arteries and a higher coronary artery calcium score is ...
J. R. Bosdriesz   +2 more
doaj   +1 more source

Renal Clearable Luminogenic Reporter for Ultrasensitive Influenza Virus Imaging and Efficient Antiviral Therapies Monitoring in Living Mice

open access: yesAdvanced Science, EarlyView.
A viral luminogenic reporter with chemiluminescence/fluorescence dual‐response and efficient renal clearance was developed for non‐invasive imaging and urinalysis of H1N1 virus protease, allowing for remote detection of H1N1 virus infections and monitoring of antiviral therapeutic efficacy in living mice.
Bankang Ruan   +9 more
wiley   +1 more source

Long-term renal outcome in methylmalonic acidemia in adolescents and adults

open access: yesOrphanet Journal of Rare Diseases, 2021
Background Chronic kidney disease (CKD) is one of the main long-term prognosis factors in methylmalonic acidemia (MMA), a rare disease of propionate catabolism.
Myriam Dao   +11 more
doaj   +1 more source

ANGPTL4 Exacerbates Renal Injury in Diabetic Kidney Disease by Impairing Podocyte Lipophagy via Compromised Lysosomal Degradative Function

open access: yesAdvanced Science, EarlyView.
In diabetic kidney disease, elevated podocyte ANGPTL4 is linked to reduced TFEB nuclear localization and compromised lysosomal degradative function. These changes impair podocyte lipophagy and promote lipid‐droplet accumulation and podocyte injury, which may contribute to renal injury progression.
Xiaojing Liu   +7 more
wiley   +1 more source

Farnesyltransferase Enables Modular Assembly of Dual‐Functional Nanobody Conjugates for in Vivo Imaging of Inflammation

open access: yesAngewandte Chemie, EarlyView.
A modular farnesyltransferase‐based chemoenzymatic platform enables fast, site‐specific labeling of nanobodies for PET imaging of inflammation. CD11b‐targeted PET agents selectively image myeloid‐driven inflammation, while CD45‐targeted PET agents provide sensitive whole‐body immune mapping.
Sneha Venkatachalapathy   +7 more
wiley   +2 more sources

Association of urinary calprotectin with estimated glomerular filtration rate.

open access: yes, 2014
A. Dot plot depicting the significant association of urinary calprotectin levels (log scale) with estimated glomerular filtration rate (eGFR) four weeks after transplantation.
Walter Zidek (95912)   +8 more
core   +1 more source

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