Results 191 to 200 of about 12,163 (219)

Exposure‐adjusted safety and efficacy of GLP‐I and GLP‐1/GIP receptor agonists compared with non‐GLP‐I for weight management and type 2 diabetes: Based on FDA medical and statistical reports of 34 280 safety and 36 312 efficacy subjects

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims This work aimed to contextualize glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) and glucose‐dependent insulinotropic polypeptide (GIP) receptor agonists safety and efficacy regarding weight management (WM); we analysed Food and Drug Administration (FDA) Medical Reviews to analyse 14 medications using patient‐exposure year normalization and ...
Aishwarya Prasad   +4 more
wiley   +1 more source
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Association between estimated glucose disposal rate and subclinical coronary atherosclerosis

Nutrition, Metabolism and Cardiovascular Diseases
The estimated glucose disposal rate (eGDR) is an easily accessible clinical parameter for assessing insulin resistance in patients with diabetes mellitus. In this study, we aimed to investigate the link between eGDR and subclinical coronary atherosclerosis in an asymptomatic middle-aged Korean population.This study involved 4004 subjects who underwent ...
Yun Kyung Cho, Eun Hee Kim, Min Jung Lee
exaly   +3 more sources

Associations of insulin resistance estimated by glucose disposal rate with frailty progression

Archives of Gerontology and Geriatrics
To investigate the relationship between estimated glucose disposal rates (eGDR) and the progression of frailty, using longitudinal data.We analyzed four waves of data from the China Health and Retirement Longitudinal Study (CHARLS) from 2011 to 2018, involving 6,778 middle-aged and older adults.
Jiayu Sun, Xiaoming Guo, Lina Meng
exaly   +3 more sources

Exploring Insulin Resistance in Adults With Type 1 Diabetes: The Role of the Estimated Glucose Disposal Rate and the Triglyceride Glucose Index

Diabetes/Metabolism Research and Reviews
ABSTRACT Aims People with type 1 diabetes (T1D) who exhibit insulin resistance present a high cardiovascular risk. Several markers, including the estimated Glucose Disposal Rate (eGDR) and Triglyceride‐Glucose (TyG) index, have been developed for measuring insulin resistance.
Antonietta Monda   +2 more
exaly   +4 more sources

Estimated glucose disposal rate predicts mortality in adults with type 1 diabetes

Diabetes, Obesity and Metabolism, 2017
Aims This study aimed to investigate the association between insulin resistance as determined by the estimated glucose disposal rate (eGDR), and survival in adults with type 1 diabetes (T1D) in Sweden. Material and Methods Using the ...
Thomas, Nyström   +4 more
openaire   +2 more sources

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