Results 131 to 140 of about 166,390 (310)

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Maximum Likelihood with Estimating Equations

Methods, like Maximum Empirical Likelihood (MEL), that operate within the Empirical Estimating Equations (E3) approach to estimation and inference are challenged by the Empty Set Problem (ESP).
Grendar, Marian, Judge, George G.
core   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Prognostic Values of Three Equations in Estimating Glomerular Filtration Rates of Patients Undergoing Off-Pump Coronary Artery Bypass Grafting

Therapeutics and Clinical Risk Management, 2020
Zhi Li,1,* Wen Ge,2,* Chunyan Han,3,* Mengwei Lv,4,5,* Yanzhong He,5 Juntao Su,6 Ban Liu,3 Yangyang Zhang5 1Department of Cardiovascular Surgery, Jiangsu Province Hospital, The First Affiliated Hospital of Nanjing Medical University, Nanjing, People ...
Li Z, Ge W, Han C, Lv M, He Y, Su J, Liu B, Zhang Y   +7 more
doaj  

Renal function estimating equations performance during pregnancy and postpartum. [PDF]

Pharmacotherapy, 2023
Zaghloul DE, Ryu R, Kestenbaum B, Smith C, Fay E, Hebert MF.   +5 more
europepmc   +1 more source

Estimates for nonlinear parabolic equations.

, 1999
Summary: We study smooth non-negative solutions of the equation \(u_t=\partial_j a_j(u,\nabla u)+a_0(u,\Delta u)\) in the strip \(S_T= \mathbb{R}^d\times (0,T)\), \(d\geq 1\). A regularizing effect, pointwise estimates and gradient estimates are obtained.
Fabricant, A., Marinov, M., Rangelov, T.
openaire   +2 more sources

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source

Estimating equations for parameters in stochastic growth models from tag-recapture data

, 1999
James (1991, Biometrics 47, 1519-1530) constructed unbiased estimating functions for estimating the two parameters in the von Bertalanffy growth curve from tag-recapture data. This paper provides unbiased estimating functions for a class of growth models
Wang, Y-G., Wang, Y. G.
core   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source

Iterative methods for nonlinear equations in a coupled system: Using modified homotopy perturbation

Ain Shams Engineering Journal
Nonlinear equations arise in various branches of applied sciences where the real-world problems cannot be formulated accurately in linear forms. It is a fascinating and thrilling task to develop numerical methods for estimating the roots of nonlinear ...
Muhammad Saqib, Shahida Bashir, Taha Radwan, Rabab Alharbi, Hamiden Abd El-Wahed Kahilfa, Rizwan Gul   +5 more
doaj   +1 more source