Results 51 to 60 of about 841,625 (297)

Energy Norms and the Stability of the Einstein Evolution Equations [PDF]

, 2002
The Einstein evolution equations may be written in a variety of equivalent analytical forms, but numerical solutions of these different formulations display a wide range of growth rates for constraint violations.
A. Abrahams, A. Anderson, A. Anderson, A. Gullstrand, A.M. Knapp, C. Bona, C. Bona, C. Gundlach, E. Seidel, F.B. Estabrook, G. Calabrese, G. Calabrese, G. Yoneda, G. Yoneda, G. Yoneda, G.B. Cook, H. Friedrich, H. Shinkai, H. Shinkai, K. Martel, L.E. Kidder, L.E. Kidder, Lee Lindblom, M. Alcubierre, M. Alcubierre, M. Alcubierre, M. Alcubierre, M. Alcubierre, M. Alcubierre, M. Shibata, M.A. Scheel, M.A. Scheel, M.A. Scheel, M.A. Scheel, M.A.G. Bonilla, M.H.P.M. van Putten, M.S. Iriondo, Mark A. Scheel, O. Sarbach, P. Anninos, P. Laguna, P. Painlevé, S. Brandt, S. Frittelli, S. Frittelli, S. Frittelli, T.W. Baumgarte, Y. Choquet-Bruhat   +47 more
core   +2 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Pathway analysis of rare variants for the clustered phenotypes by using hierarchical structured components analysis

BMC Medical Genomics, 2019
Backgrounds Recent large-scale genetic studies often involve clustered phenotypes such as repeated measurements. Compared to a series of univariate analyses of single phenotypes, an analysis of clustered phenotypes can be useful for substantially ...
Sungyoung Lee, Sunmee Kim, Yongkang Kim, Bermseok Oh, Heungsun Hwang, Taesung Park   +5 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

BB: An R Package for Solving a Large System of Nonlinear Equations and for Optimizing a High-Dimensional Nonlinear Objective Function

Journal of Statistical Software, 2009
We discuss R package BB, in particular, its capabilities for solving a nonlinear system of equations. The function BBsolve in BB can be used for this purpose.
Ravi Varadhan, Paul Gilbert
doaj  

Hydrodynamic limit for the velocity flip model [PDF]

, 2013
We study the diffusive scaling limit for a chain of $N$ coupled oscillators. In order to provide the system with good ergodic properties, we perturb the Hamiltonian dynamics with random flips of velocities, so that the energy is locally conserved.
C. Bernardin, C. Bernardin, C. Bernardin, C. Landim, C. Landim, C. Tremoulet, G. Basile, H.T. Yau, J. Fritz, M. Simon, S. Olla   +10 more
core   +5 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Influence of iodine intake on thyroid volume among students aged 8–10 years in a district of Beijing from 2022 to 2024 based on a generalized estimating equation model

Zhongguo gonggong weisheng
ObjectiveTo assess iodine intake levels and their impact on thyroid volume in children aged 8–10 years in a district of Beijing city from 2022 to 2024.
Zhilin WU, Yubin ZHANG, Chao HE, Wenzeng ZHANG   +3 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source