Results 61 to 70 of about 166,390 (310)

Parameter Estimation Based on Cumulative Kullback–Leibler Divergence

Revstat Statistical Journal, 2021
In this paper, we propose some estimators for the parameters of a statistical model based on Kullback–Leibler divergence of the survival function in continuous setting and apply it to type I censored data.
Yaser Mehrali , Majid Asadi
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Unbiased estimating equations from working correlation models for irregularly timed repeated measures

, 2004
The method of generalized estimating equations (GEEs) has been criticized recently for a failure to protect against misspecification of working correlation models, which in some cases leads to loss of efficiency or infeasibility of solutions.
Wang, You-Gan, Carey, V.J., Carey, Vincent J., Wang, Y.-G.   +3 more
core   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

BB: An R Package for Solving a Large System of Nonlinear Equations and for Optimizing a High-Dimensional Nonlinear Objective Function

Journal of Statistical Software, 2009
We discuss R package BB, in particular, its capabilities for solving a nonlinear system of equations. The function BBsolve in BB can be used for this purpose.
Ravi Varadhan, Paul Gilbert
doaj  

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Influence of iodine intake on thyroid volume among students aged 8–10 years in a district of Beijing from 2022 to 2024 based on a generalized estimating equation model

Zhongguo gonggong weisheng
ObjectiveTo assess iodine intake levels and their impact on thyroid volume in children aged 8–10 years in a district of Beijing city from 2022 to 2024.
Zhilin WU, Yubin ZHANG, Chao HE, Wenzeng ZHANG   +3 more
doaj   +1 more source

Generalized Estimating Equations.

, 2013
Generalized Estimating Equations.
Joshua W. Buckholtz (371128), Michael T. Treadway (371126), David H. Zald (215725), Warren E. Lambert (371131), Ashley N. Schwartzman (371130)   +4 more
core   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Harnack estimate for the Endangered Species Equation [PDF]

Proceedings of the American Mathematical Society, 2015
We prove a differential Harnack inequality for the Endangered Species Equation, a nonlinear parabolic equation. Our derivation relies on an idea related to the parabolic maximum principle. As an application of this inequality, we will show that positive solutions to this equation must blowup in finite time.
Cao, Xiaodong, Cerenzia, Mark, Kazaras, Demetre   +2 more
openaire   +3 more sources