Tumor mutational burden as a determinant of metastatic dissemination patterns
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
Nonparametric option pricing with no-arbitrage constraints [PDF]
We propose a completely kernel based method of estimating the call price function or the state price density of options. The new estimator of the call price function fulfills the constraints like monotonicity and convexity given in Breeden and ...
Birke, Melanie, Pilz, Kay F.
core
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Estimating a Polya frequency function$_2$ [PDF]
Jayanta Kumar Pal +2 more
openalex +1 more source
Estimating Brazilian Potential Output: A Production Function Approach [PDF]
Estimating potential output is at the same time one of the issues of greatest uncertainty in economics and greatest importance for policymakers, an unpleasant combination.
Tito Nícias Teixeira da Silva Filho
core
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Automated contouring of non-contrast echocardiograms result in similar estimates of left ventricular function to manually contoured contrast-enhanced images in chemotherapy patients [PDF]
Ashley P. Akerman +10 more
openalex +1 more source
Further development of an algorithm for the nonlinear stability analysis of the orbiting astronomical observatory paired-tracker control system Final report [PDF]
Algorithm development for estimating domain of attraction of OAO paired-tracker equilibrium state with Liapunov ...
Chomas, A. +4 more
core +1 more source
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Mei Guo,1 Jian-Ying Niu,2 Xian-Wu Ye,2 Xiao-Jie Han,2 Ying Zha,2 Yang Hong,2 Hong Fang,3 Yong Gu2,4 1Zhongshan-Xuhui Hospital, Affiliated with Fudan University, 2The Fifth People’s Hospital of Shanghai, Fudan University, 3Shanghai Minhang Center ...
Guo M +7 more
doaj

