Results 101 to 110 of about 693,040 (378)

A taxonomy of estimator consistency on discrete estimation problems [PDF]

open access: yesarXiv, 2019
We describe a four-level hierarchy mapping both all discrete estimation problems and all estimators on these problems, such that the hierarchy describes each estimator's consistency guarantees on each problem class. We show that no estimator is consistent for all estimation problems, but that some estimators, such as Maximum A Posteriori, are ...
arxiv  

Identification of novel small molecule inhibitors of ETS transcription factors

open access: yesFEBS Letters, EarlyView.
ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla   +9 more
wiley   +1 more source

Development of adaptive sideslip angle estimator

open access: yesJournal of Advanced Mechanical Design, Systems, and Manufacturing, 2016
The sideslip angle is used to control a vehicle for safety, however, it is hard to estimate the sideslip angle. In many researches, the estimator needs many unattainable variables, such as yaw inertia or cornering stiffness, to estimate the sideslip ...
ChanHo PARK   +4 more
doaj   +1 more source

Synthetic estimation for the complier average causal effect [PDF]

open access: yesarXiv, 2019
We propose an improved estimator of the complier average causal effect (CACE). Researchers typically choose a presumably-unbiased estimator for the CACE in studies with noncompliance, when many other lower-variance estimators may be available. We propose a synthetic estimator that combines information across all available estimators, leveraging the ...
arxiv  

The Saccharomyces cerevisiae amino acid transporter Lyp1 has a broad substrate spectrum

open access: yesFEBS Letters, EarlyView.
In Saccharomyces cerevisiae, Yeast Amino acid Transporter family members mediate the import of amino acids, ranging from substrate specialists to generalists. Here, we show that the specialist transporter, Lyp1, has a broader substrate spectrum than previously described, with affinity constants spanning from micromolar to millimolar.
Foteini Karapanagioti   +3 more
wiley   +1 more source

Estimation in dynamic panel data models: Improving on the performance of the standard GMM estimator

open access: yes, 2000
This chapter reviews developments to improve on the poor performance of the standard GMM estimator for highly autoregressive panel series. It considers the use of the ‘system’ GMM estimator that relies on relatively mild restrictions on the initial ...
R. Blundell   +2 more
semanticscholar   +1 more source

The cytoskeletal control of B cell receptor and integrin signaling in normal B cells and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley   +1 more source

Small area estimation in the case of nonesponse

open access: yesLietuvos Matematikos Rinkinys, 2009
In this paper the effect of model and nonresponseadjustment on different types of estimators for the totals of small area domains is examined. The empirical results are based on Monte Carlo simulations with repeated samples drawn from a finite population
Vilma Nekrašaitė-Liegė
doaj   +1 more source

Flow‐based immunomagnetic enrichment of circulating tumor cells from diagnostic leukapheresis product

open access: yesMolecular Oncology, EarlyView.
The number of circulating tumor cells obtained from prostate cancer patients was increased approximately 5‐fold compared to regular CellSearch when processing 2 mL diagnostic leukapheresis material aliquots and increased by 44‐fold when processing 20 mL DLA aliquots using the flow enrichment target capture Halbach‐array.
Michiel Stevens   +8 more
wiley   +1 more source

A nonparametric super-efficient estimator of the average treatment effect [PDF]

open access: yesarXiv, 2019
Doubly robust estimators of causal effects are a popular means of estimating causal effects. Such estimators combine an estimate of the conditional mean of the outcome given treatment and confounders (the so-called outcome regression) with an estimate of the conditional probability of treatment given confounders (the propensity score) to generate an ...
arxiv  

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