Results 191 to 200 of about 994,443 (373)

Landscape of BRAF transcript variants in human cancer

Molecular Oncology, EarlyView.
We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda, Danilo Tatoni, Gianluca Mattei, Alberto Magi, Romina D'Aurizio, Laura Poliseno   +5 more
wiley   +1 more source

Comment on "Do we need flexible machine-learning algorithms to assess the effect of long-term exposure to fine particulate matter on mortality?" [PDF]

Environ Epidemiol
Williams N, Rudolph KE, Díaz I.
europepmc   +1 more source

On the Admissibility of Invariant Estimators of One or More Location Parameters

, 1966
Lawrence D. Brown
openalex   +1 more source

A Family of Minimax Estimators in Some Multiple Regression Problems [PDF]

, 1979
Yoshikazu Takada
openalex   +1 more source

Data‐driven discovery of gene expression markers distinguishing pediatric acute lymphoblastic leukemia subtypes

Molecular Oncology, EarlyView.
This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh, Nikola Tom, Anna Schrøder Lassen, Helene Brasch Lind Petersen, Ulrik Kristoffer Stoltze, Karin Wadt, Kjeld Schmiegelow, Matteo Tiberti, Elena Papaleo   +8 more
wiley   +1 more source

Wild bootstrap for counting process-based statistics: a martingale theory-based approach. [PDF]

Lifetime Data Anal
Dietrich MT, Dobler D, de Gunst MCM.
europepmc   +1 more source

Relative Rate of in Vitro Cellulose Disappearance as a Possible Estimator of Digestible Dry Matter Intake

, 1969
Sukhpal Singh Gill, H.R. Conrad, J.W. Hibbs   +2 more
openalex   +1 more source

UNIFORM CONVERGENCE OF AN ESTIMATOR OF A DISTRIBUTION FUNCTION [PDF]

, 1973
Hajime Yamato
openalex   +1 more source

TRPM8 levels determine tumor vulnerability to channel agonists

Molecular Oncology, EarlyView.
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo, Francesco Giuseppe Carbone, Kristi Buzo, Nicole Annesi, Sacha Genovesi, Annalisa Lorenzato, Karen Widmann, Michela Libergoli, Elisa Marmocchi, Giovanni Bertalot, Alberto Brolese, Mauro Giulio Papotti, Luca Molinaro, Orazio Caffo, Mattia Barbareschi, Alberto Bardelli, Alessandro Romanel, Sabrina Arena, Andrea Lunardi   +18 more
wiley   +1 more source

New two parameter hybrid estimator for zero inflated negative binomial regression models. [PDF]

Sci Rep
Almulhim FA, Nagy M, Hammad AT, Mansi AH, Mekiso GT, El-Raouf MMA.   +5 more
europepmc   +1 more source