Enhancing precision in breast cancer diagnosis using Tailored Ratio-Integrated Variance Estimation using Neyman allocation Implementation(TRIVENI). [PDF]
Sci RepTriveni GRV, Danish F, Reddy VRK.
europepmc +1 more source
Molecular Oncology, EarlyView.Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed +8 more
wiley +1 more source
A Bound for the Euclidean Norm of the Difference Between the Least Squares and the Best Linear Unbiased Estimators [PDF]
, 1978 Jerzy K. Baksalary, R. Kala
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Delay-Compensated Lane-Coordinate Vehicle State Estimation Using Low-Cost Sensors. [PDF]
Sensors (Basel)Kim M, Kang W, Ahn C.
europepmc +1 more source
Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
Molecular Oncology, EarlyView.GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski +19 more
wiley +1 more source
Deriving Unbiased Risk Estimators of Multinormal Mean and Regression Coefficient Estimators Using Zonal Polynomials [PDF]
, 1978 Jim Zidek
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Predicting road adhesion coefficient with a fusion strategy of SHAP dynamic parameters. [PDF]
Sci RepGong Y, Du Q, Wang F, Zhang L.
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A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
Molecular Oncology, EarlyView.We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
wiley +1 more source