Results 191 to 200 of about 147,124 (262)

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source

Performance of Cardiovascular Disease (CVD) Risk Assessment Tools in Clinical Practice - Agreement Between Different CVD Risk Scores Among Patients Attending NCD Clinic in a Tertiary Care Setting: A Prospective Observational Study. [PDF]

Int J Prev Med
Pal D, Suresh S, Priyadharshini A, Das K, Behera P, Taywade M, Patro BK.   +6 more
europepmc   +1 more source

A role for eIF5A in translational control of stress‐inducible proteins in multiple myeloma cell lines

Molecular Oncology, EarlyView.
Loss of eIF5A rewires thapsigargin‐mediated endoplasmic reticulum stress responses in multiple myeloma cells by selective translation of mRNA transcripts, consequently dampening thapsigargin‐induced unfolded protein response (UPR) activation and shifting the balance from induction of apoptosis toward cell survival and proliferation.
Demi Both, Ingrid A. M. Derks, Raphaël Vanleyssem, Marine Leclercq, Najla El Hachem, Pierre Close, Eric Eldering, Marco Vincent Haselager   +7 more
wiley   +1 more source

Development of a mixed-effects longitudinal spline regression method for growth data analysis. [PDF]

MethodsX
Bangsawang IL, Islamiyati A, Herdiani ET.   +2 more
europepmc   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

Molecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira, Ana Teixeira‐Marques, Rui Freitas, João A Carvalho, Sara Monteiro‐Reis, Giorgio I. Russo, Rui Henrique, Carmen Jerónimo   +7 more
wiley   +1 more source

Improving Sensitivity Analysis By Synthesizing Randomized Clinical Trials With Limited Overlap. [PDF]

Stat Med
Jiang K, Hu W, Lai X, Yang S, Zhou XH.
europepmc   +1 more source

A k-mer-based estimator of the substitution rate between repetitive sequences. [PDF]

Algorithms Mol Biol
Wu H, Blanca A, Medvedev P.
europepmc   +1 more source

Causal effect on the number of life years lost due to a specific event: average treatment effect and variable importance. [PDF]

Lifetime Data Anal
Ziersen SC, Martinussen T.
europepmc   +1 more source

Inverse-Probability-Weighted Kernel Estimation of Regression Derivatives Under Missing-at-Random Responses for Stationary Ergodic Processes. [PDF]

Entropy (Basel)
Bouzebda S, Didi S.
europepmc   +1 more source