Chimeric diphtheria toxin–CCL8 cytotoxic peptide for breast cancer management
DTCCL8 is a recombinant fusion toxin that targets cancer cells expressing chemokine receptors. By combining diphtheria toxin with CCL8, DTCCL8 binds to multiple receptors on tumor cells and induces selective cytotoxicity. This strategy enables receptor‐mediated targeting of cancer and may support the development of chemokine‐guided therapeutics ...
Bernardo Chavez +5 more
wiley +1 more source
A Comparison of Variance Component Estimators
R. R. Corbeil, S. R. Searle
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UNIFORM CONVERGENCE OF AN ESTIMATOR OF A DISTRIBUTION FUNCTION [PDF]
Hajime Yamato
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The Integrated Disturbance Estimation and Non-Singular Terminal Sliding Mode Longitudinal Motion Controller for Low-Speed Autonomous Electric Vehicles. [PDF]
Li B +6 more
europepmc +1 more source
ITGAV and SMAD4 influence the progression and clinical outcome of pancreatic ductal adenocarcinoma
In SMAD4‐positive pancreatic ductal adenocarcinoma (PDAC), integrin subunit alpha V (ITGAV) activates latent TGF‐β, which binds to the TGF‐β receptor and phosphorylates SMAD2/3. The activated SMAD2/3 forms a complex with SMAD4, and together they translocate to the nucleus, modulating gene expression to promote proliferation, migration, and invasion. In
Daniel K. C. Lee +9 more
wiley +1 more source
Inadmissibility of a Class of Estimators of a Normal Quantile [PDF]
James V. Zidek
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Innovative memory-type calibration estimators for better survey accuracy in stratified sampling. [PDF]
Minhas KS +5 more
europepmc +1 more source
This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima +6 more
wiley +1 more source
New Fast Optimal White-Noise Estimators for Deconvolution
Jerry M. Mendel, John Kormylo
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BERRY-ESSEEN TYPE BOUND FOR DENSITY ESTIMATORS OF STATIONARY MARKOV PROCESSES [PDF]
Б. Л. С. Пракаса Рао
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