Results 81 to 90 of about 994,443 (373)

Efficient implementation of Markov chain Monte Carlo when using an unbiased likelihood estimator [PDF]

open access: yes, 2012
When an unbiased estimator of the likelihood is used within a Metropolis–Hastings chain, it is necessary to trade off the number of Monte Carlo samples used to construct this estimator against the asymptotic variances of the averages computed under this ...
A. Doucet   +3 more
semanticscholar   +1 more source

On Bayes estimates

open access: yesJournal of Multivariate Analysis, 1973
AbstractIn this paper the author tries to give general conditions for the existence of Bayes estimates and for the consistency of sequences of Bayes estimates.In Section 3 we prove existence theorems for Bayes estimates, which contain those of DeGroot and Rao [3], as a special case.
openaire   +3 more sources

The cytoskeletal control of B cell receptor and integrin signaling in normal B cells and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley   +1 more source

Interaction vesicles as emerging mediators of host‐pathogen molecular crosstalk and their implications for infection dynamics

open access: yesFEBS Letters, EarlyView.
Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke   +2 more
wiley   +1 more source

MetaAnaly: The platform-independent computational tool for meta-analysis in the paradigm of new statistics [PDF]

open access: yesNetwork Biology
Meta-analysis is a statistical method used in systematic review to quantitatively integrate the results of multiple related studies to obtain a pooled result that can represent these studies. Meta-analysis overcomes the limitations of traditional reviews
WenJun Zhang
doaj  

Decoding the dual role of autophagy in cancer through transcriptional and epigenetic regulation

open access: yesFEBS Letters, EarlyView.
Transcriptional and epigenetic regulation controls autophagy, which exerts context‐dependent effects on cancer: Autophagy suppresses tumorigenesis by maintaining cellular homeostasis or promotes tumor progression by supporting survival under stress. In this “In a Nutshell” article, we explore the intricate mechanisms of the dual function of autophagy ...
Young Suk Yu, Ik Soo Kim, Sung Hee Baek
wiley   +1 more source

Autophagy in cancer and protein conformational disorders

open access: yesFEBS Letters, EarlyView.
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley   +1 more source

Experimental investigation of active yaw moment control system using a momentum wheel

open access: yesSystems Science & Control Engineering, 2017
Active yaw moment control is one of the most effective methods to improve the lateral stability and safety of vehicle. In this method, the overall yaw moment of the vehicle is modified by applying the corrective yaw moment generated by the systems that ...
Ankur Arora   +2 more
doaj   +1 more source

Existence of an Unbiased Consistent Entropy Estimator for the Special Bernoulli Measure

open access: yesМоделирование и анализ информационных систем, 2019
Let \(\Omega = A^N\) - be a space of right-sided infinite sequences drawn from a finite alphabet \(A = \{0,1\}\), \(N = {1,2,\dots} \), \[\rho(\boldsymbol{x},\boldsymbol{y}) = \sum_{k=1}^{\infty}|x_{k} - y_{k}|2^{-k} \] - a metric on \(\Omega\), and ...
Evgeniy A. Timofeev
doaj   +1 more source

On the estimation of the derivatives of a function with the derivatives of an estimate

open access: yesJournal of Multivariate Analysis, 1989
Let \({\tilde \theta}{}_ n(x)\) be an estimator of a smooth function \(\theta\) (x). It is proved that \(\theta\) (x) can be estimated easier than its derivative \(\theta^{(s)}(x)\), providing for \(\| {\hat \theta}_ n^{(s)}-\theta^{(s)}\|_ q\) an upper bound that depends on \(\| {\hat \theta}_ n-\theta \|_ q\).
openaire   +4 more sources

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