Results 41 to 50 of about 56,076 (246)

Are There Causal Associations Between Obsessive‐Compulsive Disorder and Cardiometabolic Phenotypes? A Genetic Correlation and Bi‐Directional Mendelian Randomization Study

open access: yesAmerican Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT In epidemiological studies, obsessive‐compulsive disorder (OCD) is robustly associated with increased risk of cardiometabolic disorders, including cardiovascular diseases, type 2 diabetes, and obesity. However, the mechanisms behind these associations are unclear. We conducted genetic correlation analyses to explore shared genetic etiology and
Robyn E. Wootton   +217 more
wiley   +1 more source

‘The Other Parent’: A Critical Policy Analysis of Fatherhood Discourses in the Australian Government's Paid Parental Leave Scheme

open access: yesAustralian Journal of Social Issues, EarlyView.
ABSTRACT The Australian paid parental leave (PPL) government scheme aims to support working parents through financial assistance and the promotion of gender equality in caregiving responsibilities. However, the scheme's implementation has been critiqued for its gendered design, which marginalises fathers and reinforces traditional gender roles.
Lily Lewington   +2 more
wiley   +1 more source

The Role of the Elites in Choosing the Foreign Policy Priorities of the Baltic States

open access: yesRUDN Journal of Political Science, 2020
The author analyzed the role of the elites of the Baltic countries in the choice of foreign policy priorities in the period after the declaration of independence.
Vadim A. Smirnov
doaj   +1 more source

Proteinvermittelte Kupfer‐Redoxregulation: Rolle von Disulfidbrücken und allosterischer Modulation

open access: yesAngewandte Chemie, EarlyView.
Copper binding triggers structural changes that expose a reactive disulphide bridge, enabling intrinsic Cu(II) reduction in folded proteins. SAXS, XAS, and QM/MM simulations reveal how globular proteins such as HSA and SOD1 employ disulphide‐mediated dynamics to modulate site accessibility and control copper redox chemistry.
Rebecca Sternke‐Hoffmann   +9 more
wiley   +1 more source

Protein‐Driven Copper Redox Regulation: Uncovering the Role of Disulphide Bonds and Allosteric Modulation

open access: yesAngewandte Chemie International Edition, EarlyView.
Copper binding triggers structural changes that expose a reactive disulphide bridge, enabling intrinsic Cu(II) reduction in folded proteins. SAXS, XAS, and QM/MM simulations reveal how globular proteins such as HSA and SOD1 employ disulphide‐mediated dynamics to modulate site accessibility and control copper redox chemistry.
Rebecca Sternke‐Hoffmann   +9 more
wiley   +1 more source

Space-time correlation development of the lake levels change during the late glacial and holocene of the Baltic Lake Districts

open access: yesЖурнал Белорусского государственного университета: География, геология, 2017
Inter-regional correlation and comparison of paleogeographic events on the basis of a common methodological approach in the interpretation of geological, geochemical and palaeobotanical data on the example of the Baltic Lake District was carried out. The
Aliaksei A. Novik
doaj  

Deterrence Dilemma in Latvia and Estonia: Finding the Balance between External Military Solidarity and Territorial Defence

open access: yesJournal on Baltic Security, 2017
While potential threats from Russia and NATO collective defence commitments are similar for Latvia and Estonia, both countries have adopted different approaches in the balancing exercise between territorial defence and military solidarity ...
Andžāns Māris, Veebel Viljar
doaj   +1 more source

Do drugs approved via expedited approval pathways have therapeutic advantages? A systematic review and meta‐analysis

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Regulators use expedited approval pathways to speed market approval and patient access to promising new drugs. However, there is uncertainty about whether these pathways are successful in approving drugs with significant therapeutic advantages. This systematic review aims to examine the safety, effectiveness and cost‐effectiveness of drugs approved via
Ashleigh Hooimeyer   +4 more
wiley   +1 more source

Estonia And UNIFIL: The Benefits to a Small State of UN Peacekeeping

open access: yesJournal on Baltic Security, 2017
This article considers Estonia’s contribution, since May 2015, of an infantry company to the Finnish contingent of the Finnish/Irish battalion of the United Nations Interim Force in Lebanon.
Lawrence Tony
doaj   +1 more source

Sustaining the teaching profession: Innovating the ‘golden thread’ in university‐led teacher education

open access: yesBritish Educational Research Journal, EarlyView.
Abstract This paper examines the implications of England's ‘golden thread’ policy framework for teacher education, which describes a state‐mandated, linear model of professional learning from initial teacher training and education through to continuing professional development.
Amanda Nuttall   +3 more
wiley   +1 more source

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