Results 111 to 120 of about 213,022 (296)
Selective N‐Functionalization of Pyrazoles
European Journal of Organic Chemistry, EarlyView.This review traces the evolution of regioselective N‐functionalization strategies for pyrazoles, a key class of nitrogen heterocycles widely used in medicinal chemistry. Due to rapid tautomerism, N‐functionalization often lacks selectivity, leading to poor and unpredictable regioisomeric outcomes.
Lucas Popek +2 more
wiley +1 more source
, 2019 Owing to its critical role in the development of female reproductive tissues and as a clinical biomarker, there is an urgent need to develop a rapid and cost-effective method to sensitively detect 17β-estradiol (E2).
Shuai Sun (775057) +17 more
core +1 more source
Monthly or menstrual? A scoping review of catamenial epilepsy and non‐menstrual seizure rhythms
Epilepsia, EarlyView.Abstract Objective Despite the reported high prevalence of catamenial epilepsy (CE), the condition remains poorly defined, with lack of consensus on what entails a menstrual‐related seizure exacerbation. Emerging evidence of multiday cycles of seizure activity, including about‐monthly cycles, present in both men and women, further confound the ...
Victoria Wong +4 more
wiley +1 more source
Nomegestrol acetate-17b-estradiol for oral contraception
, 2013 Anne Burke Johns Hopkins University School of Medicine, Baltimore, MD, USAAbstract: Oral contraceptives remain a popular method of contraception over 50 years after their introduction.
Burke A
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Epilepsia Open, EarlyView.Abstract Infantile epilepsy spasms syndrome (IESS), formerly known as infantile spasms or West Syndrome, is a severe epilepsy syndrome affecting about 3 in 10,000 newborns in the United States. Characterized by clusters of epileptic spasms, interictal hypsarrhythmia, and developmental delays, IESS has diverse causes, including structural‐metabolic ...
Kayla Vieira +5 more
wiley +1 more source
Status epilepticus: Updates on mechanisms and treatments
Epilepsia Open, EarlyView.Abstract Status epilepticus (SE) consists of prolonged, self‐sustaining seizures and is a common neurological emergency that causes respiratory compromise and neuronal injury. Without prompt treatment, the seizures can become resistant to benzodiazepines, leading to the progressive evolution of established, refractory, and super‐refractory SE.
Suchitra Joshi, Jaideep Kapur
wiley +1 more source
Testosterone, 17β-estradiol and pubertal growth [PDF]
, 2014 Background and aims: It is well established that the interaction of sex steroids with the growth hormone (GH)/ insulin-like growth factor 1 (IGF-1) axis is of major importance in children for normal pubertal growth.
Albin, Anna-Karin
core +1 more source
Predictors of Menopausal Symptoms in Postmenopausal Women
Journal of Mazandaran University of Medical Sciences, 2019 Background and purpose: Menopause is a normal physiological process which influences the life of many middle-aged women. Studies reported different results on the effects of various factors on severity of menopausal symptoms.
Neda Mohamadzade +4 more
doaj
Objectives:Accuracy of estradiol measurements is important but conventional proficiency testing (PT) cannot assess accuracy when possibly non-commutable samples are used and method peer-group means are the targets.
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, 2016 Equol is present in the aquatic environment via livestock waste and runoff discharge; however, it remains unclear whether it can induce gonadal intersex in fish at environmentally relevant concentrations.
Shiyi Zhang (1445722) +13 more
core +1 more source