Results 91 to 100 of about 220,059 (299)

LncRNA FLJ20021 Restrains Fibroblast Senescence and Matrix Remodeling in Pelvic Organ Prolapse by Promoting XRCC6‐Dependent ADI1 Transcription

open access: yesAdvanced Science, EarlyView.
FLJ20021 interacts with XRCC6 to regulate ADI1 transcription and downstream cellular phenotypes in hUSLFs. Reduced FLJ20021 in POP is associated with lower ADI1, increased apoptosis, senescence, and an ECM‐degrading marker profile. Conversely, FLJ20021 overexpression enhances XRCC6‐dependent ADI1 expression, reduces apoptosis and senescence, and shifts
YanFeng Yang   +4 more
wiley   +1 more source

Estradiol and chlordecone interactions with the estrogen receptor [PDF]

open access: yes, 1988
The in vivo and in vitro effects of the chlorinated pesticide, chlordecone, on the estradiol receptor of adult ovariectomized CDF-344 rats were examined.
Williams, Judy
core   +1 more source

Estrogens and gonadal function in schizophrenia and related psychoses [PDF]

open access: yes, 2011
Recent research has increasingly pointed to the importance of estrogens and the hypothalamic-pituitary-gonadal axis in schizophrenia. Specifically, there is mounting evidence from clinical, epidemiological, and basic research that estradiol, the main ...
Riecher-Rössler, Anita   +1 more
core  

Plasma Membrane Lipid Asymmetry Dynamically Regulates Passive Diffusion

open access: yesAdvanced Science, EarlyView.
Passive diffusion enables hydrophobic molecules to cross the plasma membrane and exert their biological functions. This study demonstrates that plasma membrane lipid asymmetry, dynamically regulated by lipid scrambling, determines membrane permeability to lipophilic molecules and thereby modulates their cellular activities.
Jieming Ping   +4 more
wiley   +1 more source

Nomegestrol acetate-17b-estradiol for oral contraception

open access: yes, 2013
Anne Burke Johns Hopkins University School of Medicine, Baltimore, MD, USAAbstract: Oral contraceptives remain a popular method of contraception over 50 years after their introduction.
Burke A
core  

A Novel NR3C1 Frameshift Variant Associated With Familial Glucocorticoid Resistance Syndrome: An Integrated Analysis of Steroid Profiling and Structural Modeling

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Glucocorticoid resistance syndrome (GRS) is a rare hereditary disorder caused by pathogenic variants in NR3C1, characterized by marked phenotypic heterogeneity and frequent misdiagnosis as primary aldosteronism or subclinical Cushing's syndrome.
Sufang Yun   +7 more
wiley   +1 more source

Effect of short-term phytoestrogen treatment in male rats on nitric oxide-mediated responses of carotid and cerebral arteries: Comparison with 17Beta-estradiol

open access: yes, 2004
The use of estrogen for protection against vascular dysfunction is limited due to its effects on the reproductive system, particularly in males. We postulated that daidzein, an isoflavone with estrogen-like effects on the systemic vasculature but not the
Chris Sobey (19981698)   +3 more
core  

Estradiol Binding Sites in Trout Liver [PDF]

open access: yes, 2017
application/pdfDepartmental Bulletin Paper^3H-Estradiol-17β was predominantly distributed in the cytosol and nuclear fractions when the steroid hormone was incorporated into liver cells of mature female rainbow trout in vitro.
Hamana, Koei, 2210, 2209, Suzuki, Mitsuo
core  

17Beta-estradiol modulates gastroduodenal preneoplastic alterations in rats exposed to the carcinogen N-methyl-N'-nitro-nitrosoguanidine [PDF]

open access: yes, 1999
Gastric cancers are a significant cause of morbidity worldwide. Epidemiological studies and animal models show that males have higher incidences of gastric cancers compared with females, suggesting that sex hormones may modulate gastric cancer risk.
Reyher, K K   +5 more
core   +1 more source

Estrone and estradiol concentrations in human ovaries, testes, and adrenals during the first two years of life [PDF]

open access: yes, 1987
To determine the origin of estrogens in infant blood, we measured estrone (E1) and estradiol (E2) in the gonads of 50 girls and 64 boys who died suddenly between birth and 2 yr of age as well as in the adrenals of 18 of these infant girls and 16 of the ...
Eisenmenger, Wolfgang   +4 more
core   +1 more source

Home - About - Disclaimer - Privacy