Results 81 to 90 of about 220,059 (299)

Weak if any effect of estrogen on spatial memory in rats [PDF]

, 2002
In a number of species, males appear to have spatial abilities that are superior to those of females. The favored explanation for this cognitive difference is hormonal: higher testosterone levels in males than in females.
Németh, Hajnalka, Toldi, József, Kis, Zsolt, Farkas, Tamás, Varga, Hedvig, Tóth, Tünde   +5 more
core   +1 more source

Korelasi Kadar Estradiol dan Kadar Leptin dengan Profil Lipid pada Wanita Obesitas, Overweight dan Berat Badan Normal di Kota Banda Aceh

, 2015
Background: The prevalence of obesity at woman was higher than man. Obesity related to leptin resistance that causes hipertrigliseridemia that known as an overview of lipid metabolism disorders.
Fitri, Yulia
core  

Insights from the Structure of Estrogen Receptor into the Evolution of Estrogens: Implications for Endocrine Disruption [PDF]

, 2011
In the last decade, there has been important progress in understanding the origins and evolution of receptors for adrenal steroids (aldosterone, cortisol) and sex steroids (estradiol, progesterone, testosterone) due to the sequencing of genomes from ...
Michael E. Baker
core   +1 more source

ERα–PADI4–CXCL8 Axis Drives MDSC‐Mediated Immune Evasion in Anaplastic Thyroid Carcinoma

Advanced Science, EarlyView.
MAPK‐driven ligand‐independent ERα activation drives PADI4 transcription and translation. This enzyme then modifies CXCL8 chemokines through citrullination, generating a potent chemoattractant gradient specifically for myeloid‐derived suppressor cells.
Dongdong Zhang, Ying Cai, Junbin Zhang, Jianyong Zhang, Ran Jing, Ming Cai   +5 more
wiley   +1 more source

Circulating thyrotropin is upregulated by estradiol [PDF]

, 2018
After encountering two women with serum thyrotropin (TSH) levels greater in periovulatory phase than in other days of the menstrual cycle, we hypothesized that TSH levels could be sensitive to changes in circulating estrogens in women.The objective of ...
Irene Borrielli, Giorgianni, Grazia, Vita, Roberto, Grazia Giorgianni, Roberto Vita, Le Donne, Maria, Alessandro Antonelli, Roberta Granese, Borrielli, Irene, Di Bari, Flavia, Flavia Di Bari, Grasso, Loredana, Antonelli, Alessandro, Loredana Grasso, Benvenga, Salvatore, Maria Le Donne, Salvatore Benvenga, Granese, Roberta   +17 more
core   +1 more source

Tracking CDK1 Dynamics With a Novel Biosensor Mouse and Clinical Cohorts to Predict CDK4/6 Inhibitor Sensitivity in ER+ Breast Cancer

Advanced Science, EarlyView.
Cyclin‐dependent kinase (CDK) 1 activity is a dynamic marker of treatment response in estrogen receptor positive breast cancer. Patient cohorts reveal CDK1 activity increases during progression to invasive disease, where high expression correlates with poor survival. Using a novel Cdk1 biosensor mouse alongside in vitro models, we demonstrate that CDK1
Sarah Alexandrou, Kristine J. Fernandez, Min Li Huang, Ewan K. A. Millar, Claire Vennin, Leila Eshraghi, Tan Dat Timothy Lam, Victoria Lee, Nyah C. Brooks, Janett Stoehr, Cristian Guaman Mendez, Douglas Strathdee, David Stevenson, David Herrmann, Sandra O'Toole, Paul Timpson, Max Nobis, C. Elizabeth Caldon   +17 more
wiley   +1 more source

Tumor and peritumoral tissue hormonal background features in patients with rare types of endometrial cancer

Исследования и практика в медицине
Serous endometrial intraepithelial carcinoma (SEIC) and clear cell carcinoma of the endometrium (CCEC) belong to pathogenetic type II without evidence of hyperestrogenism, are often detected late in the course of the disease, and are characterized by an ...
E. M. Frantsiyants, V. A. Bandovkina, A. P. Menshenina, T. I. Moiseenko, M. A. Rogozin, Yu. A. Pogorelova, I. V. Kaplieva, E. I. Surikova, I. V. Neskubina, N. D. Cheryarina, E. V. Verenikina   +10 more
doaj   +1 more source

WFS1 Deficiency Impairs PIAS4‐Associated SUMOylation and Increases Ubiquitin‐Mediated Spermatogenesis‐Related Protein Degradation Leading to Testicular Male Infertility

Advanced Science, EarlyView.
The findings establish a critical role for WFS1 in human male fertility. Mechanistically, WFS1 interacts with PIAS4 to promote the SUMOylation of key spermatogenesis‐associated proteins, which in turn competitively inhibits their K48‐linked ubiquitin‐mediated degradation during spermatogenesis.
Yunchuan Tian, Guicheng Zhao, Xiang Wang, Xinyao Tang, Gan Shen, Tiechao Ruan, Chuan Jiang, Shikun Zhao, Jincheng Zhang, Xinyue Cui, Liangchai Zhuo, Jun Ma, Yihong Yang, Tingting Lin, Ying Shen   +14 more
wiley   +1 more source

Structural Control of Stromal‐Immune Coupling by COL24A1 Underlies Pregnancy Maintenance

Advanced Science, EarlyView.
COL24A1 emerges as a collagen‐associated regulator of maternal‐fetal interface homeostasis. Its deficiency promotes a maladaptive TIMP1‐high stromal state, impaired ECM turnover, collagen accumulation, and stromal–immune dysregulation, contributing to pregnancy loss.
Teng Wu, Lingling Xie, Wenyi Liu, Hanjie Mo, Chengshu Xie, Jing Tang, Zhaorui Wang, Peixuan Lan, Jianping Zhang, Jie Gao, Qionglan Tang, Chunwei Cao, Hui Chen   +12 more
wiley   +1 more source

Estradiol Esterification in the Human Preovulatory Follicle.

, 2001
In the preovulatory follicle, the LH surge stimulates progesterone production, reduces estradiol synthesis, and scales up the permeability of the blood-follicle barrier.
CIGLIANO, LUISA, Paolo Abrescia, Maria Stefania Spagnuolo, M. S. SPAGNUOLO, B. DALE, Marco Balestrieri, M. BALESTRIERI, Brian Dale, ABRESCIA, PAOLO, Luisa Cigliano   +9 more
core   +3 more sources