Results 61 to 70 of about 213,022 (296)
Long term effects of aromatase inhibitor treatment in patients with aromatase excess syndrome
Frontiers in EndocrinologyIntroductionAromatase excess syndrome (AEXS) is a rare, autosomal dominant disorder, characterized by enhanced aromatization of androgens and estrogen excess.
Eleni Z. Giannopoulou +17 more
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Animals, 2021 Mammary cancer is a frequent neoplasia in female dogs, in which most important risk factors are hormonal. Sexual hormones as estradiol play an important role in mammary carcinogenesis, being able to induce carcinogenic initiation, promotion and ...
Cristian G. Torres +2 more
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Biodegradação de estrona, 17B-estradiol e 17A-etinilestradiol em sistemas aeróbios de tratamento [PDF]
, 2014 Tese (doutorado) - Universidade Federal de Santa Catarina, Centro Tecnológico, Programa de Pós-Graduação em Engenharia Ambiental, Florianópolis, 2014Os estrogênios, presentes no meio aquático como contaminantes e classificados como desreguladores ...
Bernardelli, Jossy Karla Brasil
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Advanced Science, EarlyView.A paternal glucocorticoid–sperm Gnas‐ICR axis is linked to ovarian endocrine programming in female offspring. Paternal preconception caffeine exposure elevates corticosterone, promotes sperm Gnas‐ICR hypermethylation, and is associated with ovarian Gnas upregulation, cAMP/PKA/CREB–StAR activation, enhanced estradiol synthesis, and PPP‐like phenotypes ...
Jing Huang +4 more
wiley +1 more source
Spatially Organized Human Ovarian Spheroids Instruct Endometrial Morphogenesis
Advanced Science, EarlyView.A spatially organized human follicle‐like spheroid (SPHEGaT) composed of granulosa cells (GCs) and stromal‐derived theca‐like cells (TLCs) establishes sustained steroidogenesis in vitro. When co‐cultured with human endometrial organoids (EMOs), estradiol (E2) and progesterone (P4) exchange induces secretory/progesterone‐responsive differentiation ...
Maria João Sousa +5 more
wiley +1 more source
BiomedicinesIn the skin, estradiol (E2) promotes profibrotic and proinflammatory cytokines, contributing to extracellular matrix (ECM) deposition. However, the magnitude of the response differs.
DeAnna Baker Frost +3 more
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A pilot study of the visible effects of estradiol on human intestinal cells in tissue culture [PDF]
, 1971 The purpose of this tissue culture study was to determine whether physiological levels of the steroid 17-B - estradiol would stimulate visible changes in morphology or growth of adult human fibroblastic cells derived from the large intestine, a non ...
Curtis, Linda Neskaug +1 more
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Estradiol valerate and dienogest: a new approach to oral contraception
, 2011 Jessica W Kiley, Lee P ShulmanSection of Family Planning and Contraception, Department of Obstetrics and Gynecology, Feinberg School of Medicine of Northwestern University, Chicago, IL, USAAbstract: Most combination oral contraceptives contain ethinyl ...
Jessica Kiley, Kiley JW, Shulman LP
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Advanced Science, EarlyView.Polystyrene nanoplastics disrupt pancreatic immune–endocrine homeostasis by promoting MHC‐I‐associated dendritic cell activation and inflammatory crosstalk with β cells. This immune remodeling drives β‐cell dedifferentiation, impairs insulin secretion, and aggravates metabolic dysfunction, revealing a previously unrecognized immunometabolic mechanism ...
Conghui Qiao +10 more
wiley +1 more source
LifeGlyphosate and glyphosate-based herbicides (GBHS) are the most widely used herbicides worldwide, yet their potential endocrine-disrupting effects in humans remain inadequately studied.
Wen-Yang Wu +4 more
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