Results 41 to 50 of about 158,816 (117)

Estradiol Inhibits Th17 Cell Differentiation through Inhibition of RORγT Transcription by Recruiting ERα/REA Complex to the EREs of RORγT Promoter

Journal of Immunology, 2015
The symptoms of vaginal candidiasis exacerbate in the second half of the menstrual cycle in premenopausal women when the serum estradiol level is elevated.
Rong-yi Chen, Yiming Fan, Qiuyang Zhang, Sen Liu, Qingli Li, Guo-Lin Ke, Chen Li, Z. You   +7 more
semanticscholar   +1 more source

Effects of Estradiol on Expression of Estrogen Receptor and Collagen mRNAs in Chick Skin

The Journal of Poultry Science, 2022
Skin thickness and strength differ between male and female chickens. This study aimed to clarify the effects of estradiol on the expression of estrogen receptors and collagen mRNA in chicken skin.
Shotaro Nishimura, Sayaka Arai, Mizuki Ohtani, Yuri Shimomura, Shoji Tabata   +4 more
doaj   +1 more source

Randomized Controlled Trial of Low-Dose Estradiol and the SNRI Venlafaxine for Vasomotor Symptoms

JAMA Internal Medicine, 2014
Importance Estrogen therapy is the gold standard treatment for hot flashes and night sweats, but some women are unable or unwilling to use it because of associated risks. The serotonin-norepinephrine reuptake inhibitor venlafaxine is used widely as a non-
H. Joffe, K. Guthrie, A. LaCroix, S. Reed, K. Ensrud, J. Manson, K. Newton, E. Freeman, G. Anderson, J. Larson, J. Hunt, J. Shifren, K. Rexrode, B. Caan, B. Sternfeld, J. Carpenter, L. Cohen   +16 more
semanticscholar   +1 more source

Acute progesterone feedback on gonadotropin secretion is not demonstrably altered in estradiol‐pretreated women with polycystic ovary syndrome

Physiological Reports, 2022
Women with polycystic ovary syndrome (PCOS) demonstrate gonadotropin‐releasing hormone (GnRH) pulse generator resistance to suppression with 7 days of progesterone and estradiol administration.
Su Hee Kim, Jessica A. Lundgren, James T. Patrie, Christine M. Burt Solorzano, Christopher R. McCartney   +4 more
doaj   +1 more source

Targeting metabolic pathways: a novel therapeutic direction for type 2 diabetes

Frontiers in Cellular and Infection Microbiology, 2023
BackgroundType 2 diabetes mellitus (T2DM) is a prevalent metabolic disease that causes multi-organ complications, seriously affecting patients’ quality of life and survival.
Zhihui Song, Zhihui Song, An Yan, Zehui Guo, Zehui Guo, Yuhang Zhang, Yuhang Zhang, Tao Wen, Tao Wen, Zhenzhen Li, Zhenzhen Li, Zhihua Yang, Zhihua Yang, Rui Chen, Yi Wang, Yi Wang   +15 more
doaj   +1 more source

Association between polyunsaturated fatty acid intake and estradiol levels among U.S. women

Frontiers in Nutrition
BackgroundPolyunsaturated fatty acids (PUFAs) play a crucial role in maintaining homeostasis in the body. However, research on the relationship between PUFA intake and estradiol levels is limited.
Lange Guo, Yukui Nan, Kangni Liang, Lizhong Yao, Jiuzhi Li   +4 more
doaj   +1 more source

Serum estradiol to testosterone ratio as a novel predictor of severe preeclampsia in the first trimester

The Journal of Clinical Hypertension, 2023
Preeclampsia (PE) is the most common medical complication during pregnancy and the second leading cause of maternal death worldwide. However, a better predictive model of PE remains to be explored.
Yongmei Shen, Jiasong Cao, Liying Yao, Shanshan Li, Xiaomin Zhao, Wen Li, Zhuo Wei, Lei Zhang, Jianxi Wang, Ying Chang   +9 more
doaj   +1 more source

Estradiol inhibits phosphorylation of JAK/STAT, PI3K/AKT and expression of IL-17A in mouse mononuclear cells treated with IL-36β

Pifu-xingbing zhenliaoxue zazhi, 2023
Objective To investigate the effects of β-estradiol (E2) on the phosphorylation of JAK/STAT, PI3K/AKT signaling pathways and the expression of IL-17A in mouse spleen mononuclear cells treated with IL-36β. Methods The spleens were isolated from female SPF
Shuang LIU, Shanshan YANG, Chunchan ZHENG, Sujun LUO, Na WEI, Sirui LI, Jianqiang SHI, Rongyi CHEN   +7 more
doaj   +1 more source

Long term effects of aromatase inhibitor treatment in patients with aromatase excess syndrome

Frontiers in Endocrinology
IntroductionAromatase excess syndrome (AEXS) is a rare, autosomal dominant disorder, characterized by enhanced aromatization of androgens and estrogen excess.
Eleni Z. Giannopoulou, Eleni Z. Giannopoulou, Stephanie Brandt, Stephanie Brandt, Stephanie Brandt, Stefanie Zorn, Stefanie Zorn, Stefanie Zorn, Christian Denzer, Christian Denzer, Julia von Schnurbein, Julia von Schnurbein, Maki Fukami, Alexander Kaiser, Martin Schmidt, Martin Wabitsch, Martin Wabitsch, Martin Wabitsch   +17 more
doaj   +1 more source

Hormonal Carcinogenesis in Canine Mammary Cancer: Molecular Mechanisms of Estradiol Involved in Malignant Progression

Animals, 2021
Mammary cancer is a frequent neoplasia in female dogs, in which most important risk factors are hormonal. Sexual hormones as estradiol play an important role in mammary carcinogenesis, being able to induce carcinogenic initiation, promotion and ...
Cristian G. Torres, María P. Iturriaga, Pamela Cruz   +2 more
doaj   +1 more source