Results 31 to 40 of about 213,022 (296)

Extracellular histone H3 facilitates ferroptosis in sepsis through ROS/JNK pathway

open access: yesImmunity, Inflammation and Disease, 2023
Introduction Previous evidence realized the critical role of histone in disease control. The anti‐inflammatory function of estradiol (E2) in sepsis has been documented.
Zhijun Han   +5 more
doaj   +1 more source

Interferon Genes Are Influenced by 17β-Estradiol in SLE

open access: yesFrontiers in Immunology, 2021
Recent evidence suggests the existence of a nexus between inflammatory pathways and the female sex hormone 17β-estradiol, resulting in increased interferon-stimulated genes (ISGs), autoantibodies, and dysregulation of immune cells in SLE.
Ram P. Singh   +4 more
doaj   +1 more source

An estradiol releasing, proangiogenic hydrogel as a candidate material for use in soft tissue interposition

open access: yes, 2019
Introduction and Objectives Soft tissue interposition (STI) using local and/or regional flaps is often necessary in urogenital reconstruction to stimulate wound healing and prevent recurrence.
Sheila MacNeil   +12 more
core   +1 more source

New opportunities for using transdermal forms of estradiol in ART programs

open access: yesРепродуктивная эндокринология, 2021
Objective of this review is to summarize the accumulated data on the use of estradiol transdermal gel in the form of a bottle with a pump-dispenser Oestrogel® in the treatment of "thin" endometrium and in assisted reproductive technologies (ART) programs.
V.V. Kotlik, M.I. Grytsko
doaj   +1 more source

Dose-dependent regulation of cell proliferation and collagen degradation by estradiol on ligamentum flavum

open access: yes, 2017
Background: Estradiol plays an important role in the regulation of collagen metabolism. Deficiency of estradiol has been reported to be associated with the degeneration of many connective tissues.
Chen, Mei-Hsiu;Hu, Chao-Kai;Chen, Pei-Ru;Chen, Yu-Shan;Sun, Jui-Sheng;Chen, Ming-Hong   +1 more
core   +1 more source

Avoiding touching until 60 min—contamination of transdermal estradiol gel after physical contact

open access: yesFrontiers in Endocrinology
IntroductionThis study aimed to explore the relationship between the timing of physical contact and the level of estradiol contamination in the skin after application of estradiol gel.
Yi Cao, Le Zhang, Jing Wei, Jingnan Liao
doaj   +1 more source

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

Sex Hormones, Growth Hormone, and the Cornea

open access: yesCells, 2022
The growth and maintenance of nearly every tissue in the body is influenced by systemic hormones during embryonic development through puberty and into adulthood.
Tina B. McKay   +2 more
doaj   +1 more source

Estradiol, Progesterone, and Transforming Growth Factor α Regulate Insulin-Like Growth Factor Binding Protein-3 (IGFBP3) Expression in Mouse Endometrial Cells [PDF]

open access: yes, 2009
Insulin-like growth factor 1 (IGF1) Is Involved in the proliferation of mouse and rat endometrial cells in a paracrine or autocrine manner. Insulin-like growth factor binding protein-3 (IGFBP3) modulates actions of IGFs directly or indirectly.
Takahashi, Sumio   +3 more
core   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

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