Results 31 to 40 of about 305,342 (299)

Restoration of serum estradiol and reduced incidence of miscarriage in patients with low serum estradiol during pregnancy: a retrospective cohort study using a multifactorial protocol including DHEA

open access: yesFrontiers in Reproductive Health
BackgroundLow serum estradiol in early pregnancy is associated with an elevated risk of miscarriage. We sought to determine whether efforts to restore low blood estradiol via estradiol or dehydroepiandrosterone (DHEA) supplementation would reduce the ...
Phil Boyle   +11 more
doaj   +1 more source

Influence of chronic ischemic disorders in the prostate on the development of benign prostatic hyperplasia

open access: yesИсследования и практика в медицине, 2020
Purpose of the study. To assess the degree of influence of ischemic disorders in the prostate on the level of androgens.Materials and methods. This was an experimental study that included 20 white non-linear sexually Mature rats. All animals were divided
G. E. Roitberg   +2 more
doaj   +1 more source

Estradiol pretreatment in GnRH antagonist protocol for IVF/ICSI treatment

open access: yesOpen Medicine, 2022
We conducted a systematic review and meta-analysis of all published data to determine the impact of estradiol pretreatment on reproductive outcomes and ovary stimulation characteristics for in vitro fertilization (IVF)/intracytoplasmic sperm injection ...
Zhu Shaomi   +5 more
doaj   +1 more source

Neuroprotective Effects of Estrogen Through BDNF-Transient Receptor Potential Channels 6 Signaling Pathway in the Hippocampus in a Rat Model of Perimenopausal Depression

open access: yesFrontiers in Aging Neuroscience, 2022
Estradiol (E2) has been proven to be effective in treating perimenopausal depression (PD); however, the downstream signaling pathways have not been fully elucidated. Transient receptor potential channels 6 (TRPC6) plays a vital role in promoting neuronal
Qiaoli Song   +12 more
doaj   +1 more source

17β-Estradiol Promotes Trained Immunity in Females Against Sepsis via Regulating Nucleus Translocation of RelB

open access: yesFrontiers in Immunology, 2020
Sepsis is more common among males than females, and the unequal estrogen levels have been suspected to play a vital role in gender differences. Recently, trained immunity is reported to be a novel strategy for the innate immune system to fight infection.
Zhiheng Sun   +7 more
doaj   +1 more source

Avoiding touching until 60 min—contamination of transdermal estradiol gel after physical contact

open access: yesFrontiers in Endocrinology
IntroductionThis study aimed to explore the relationship between the timing of physical contact and the level of estradiol contamination in the skin after application of estradiol gel.
Yi Cao, Le Zhang, Jing Wei, Jingnan Liao
doaj   +1 more source

Extracellular histone H3 facilitates ferroptosis in sepsis through ROS/JNK pathway

open access: yesImmunity, Inflammation and Disease, 2023
Introduction Previous evidence realized the critical role of histone in disease control. The anti‐inflammatory function of estradiol (E2) in sepsis has been documented.
Zhijun Han   +5 more
doaj   +1 more source

Interferon Genes Are Influenced by 17β-Estradiol in SLE

open access: yesFrontiers in Immunology, 2021
Recent evidence suggests the existence of a nexus between inflammatory pathways and the female sex hormone 17β-estradiol, resulting in increased interferon-stimulated genes (ISGs), autoantibodies, and dysregulation of immune cells in SLE.
Ram P. Singh   +4 more
doaj   +1 more source

Understanding the dynamics of Toll-like Receptor 5 response to flagellin and its regulation by estradiol [PDF]

open access: yes, 2017
© 2017 The Author(s). Toll-like receptors (TLRs) are major players of the innate immune system. Once activated, they trigger a signalling cascade that leads to NF-ΰ B translocation from the cytoplasm to the nucleus. Single cell analysis shows that NF-ΰ
B Calippe   +42 more
core   +5 more sources

New opportunities for using transdermal forms of estradiol in ART programs

open access: yesРепродуктивная эндокринология, 2021
Objective of this review is to summarize the accumulated data on the use of estradiol transdermal gel in the form of a bottle with a pump-dispenser Oestrogel® in the treatment of "thin" endometrium and in assisted reproductive technologies (ART) programs.
V.V. Kotlik, M.I. Grytsko
doaj   +1 more source

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