Expanding therapeutic horizons: glucagon-like peptide-1 receptor agonists and sodium glucose transporter-2 inhibitors in poly cystic ovarian syndrome: a comprehensive review including systematic review and network meta-analysis of randomized clinical trials. [PDF]
Sridharan K, Sivaramakrishnan G.
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Development of a nomogram for predicting the outcome in patients with prolonged disorders of consciousness based on the multimodal evaluative information. [PDF]
Fu J+6 more
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Variations in Volume: Breast Size in Trans Women in Relation to Timing of Testosterone Suppression.
Boogers LS+11 more
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An anti-estradiol effect of ?-estradiol-17β (?-estradiol)
Steroids, 1969Abstract The 1 -enantiomorph of estradiol-17β will inhibit the effects of estradiol-17β on uterine growth and vaginal opening in immature female mice and on the vaginal smears of spayed adult mice. The inhibitory ratios of ent - to natural estradiol are similar to ratios shown by Terenius to inhibit the incorporation of radio-active ...
Richard A. Edgren, Robert C. Jones
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Estradiol and chlordecone interactions with the estradiol receptor
Toxicology and Applied Pharmacology, 1989The in vivo and in vitro effects of the chlorinated pesticide, chlordecone, on the estradiol receptor of adult ovariectomized CDF-344 rats were examined. Chlordecone's competition with [3H]estradiol for binding to the estradiol receptor in vitro was similar whether receptors were derived from neural or uterine tissue.
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Synthesis of [2‐d]estradiol, [4‐d]estradiol, [2‐t]estradiol and [4‐t]estradiol with high specificity
Journal of Labelled Compounds and Radiopharmaceuticals, 1984Abstract17‐β‐Estradiol has been labeled in the 2 or 4 position with tritium or deuterium. Both 2‐ and 4‐iodoestradiol were prepared by treatment of estradiol with N‐iodosuccinimide in ethanol followed by chromatographic separation. Reductive dehalogenation of 2‐ and 4‐iodoestradiol with tritium gas gave [2‐t] estradiol and [4‐t] estradiol, respectively,
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Ovarian steroids, such as estradiol (E2), control a vastness of physiological processes, such as puberty, reproduction, growth, development and metabolic rate. In fact, physiological, pathological, pharmacological or genetically-induced estrogen deficiency causes increased appetite and reduced energy expenditure, promoting weight gain and ultimately ...
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An Alternative Route to 2-Bromo-Estradiols and 2-Iodo-Estradiols From Estradiol
Australian Journal of Chemistry, 1987Through careful choice of reaction conditions, alkylation of estradiol with chloromethyl methyl ether may yield either the 3,17β-bis(methoxymethy1) ether or the 3-methoxymethyl ether derivative. Treatment of either of these protected estradiols with s- butyllithium, then with trimethylsilyl chloride affords, regioselectively, the 2-trimethylsilyl
DD Ridley, DJ Pert
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