Results 61 to 70 of about 197,321 (245)
Advanced Science, EarlyView.WTAP drives cartilage regeneration by activating an LRP1‐dependent lipid metabolic program in macrophages, enhancing IL‐10 and TGF‐β secretion to promote chondrogenic differentiation. Leveraging this mechanism, virtual screening identifies LRP1‐targeting compounds that effectively stimulate cartilage repair, highlighting a druggable epigenetic ...
Chenyan Huang +6 more
wiley +1 more source
Animal Models and Experimental Medicine, EarlyView.To address the limitations of existing models, this study innovatively established a mouse model of endometriosis (EMs) capable of mimicking cyclic bleeding. Our results confirmed that this model recapitulates the complete pathological progression from ectopic lesion establishment to systemic responses, exhibiting superior clinical relevance compared ...
Yu Zhuang +7 more
wiley +1 more source
Chan–Lam Cross‐Coupling With Alkylboron Reagents: From Transmetallation to Radical Pathways
European Journal of Organic Chemistry, EarlyView.Alkylative Chan–Lam coupling overcomes intrinsic transmetallation limitations of alkylboron reagents by engaging radical pathways. Recent advances reveal how radical and radical–polar crossover mechanisms enable mild C(sp3)—heteroatom bond formation. This minireview highlights key mechanistic insights and emerging strategies that transform alkylboron ...
Nicolas G.‐Simonian +3 more
wiley +1 more source
Estudos sôbre a anemia produzida em cães por benzoato de estradiol
Memorias do Instituto Oswaldo Cruz, 1944 A anemia que se processa em caes quando se administra grandes doses de benzoato de estradiol, nao parece ser produzida por processes conhecidos de destrui?ao intra-organica. Esta substantia paraliza os fenomenos de rege¬nerate hematica, parece interferir
W. O. Cruz +2 more
doaj +1 more source
Effect of estrogen administration on middle cerebral arterial viscoelastic properties in aged female rats [PDF]
Acta Cirúrgica Brasileira, 2016 PURPOSE: To develop a model for studying cerebrovascular disease prevention in elderly women. METHODS: Sixty 18-month-old Sprague Dawley (SD) rats were randomly divided into an estrogen administration group (EA, n=30) and a non-administration group (NA,
Zhigang Qin +4 more
doaj +2 more sources
GPR30 activation decreases anxiety in the open field test but not in the elevated plus maze test in female mice [PDF]
, 2013 The GPR30 is a novel estrogen receptor (ER) that is a candidate membrane ER based on its binding to 17beta estradiol and its rapid signaling properties such as activation of the extracellular-regulated kinase (ERK) pathway.
Anchan, Divya +3 more
core +1 more source
Genes, Brain and Behavior, Volume 25, Issue 3, June 2026.In female mice, estrogen withdrawal following a hormone‐simulated pseudopregnancy is associated with increased levels of ∆FOSB in the Nucleus Accumbens Core and increased anxiety behaviors. However, using viral‐mediated expression of ∆JUND to decrease ∆FOSB‐mediated transcription in the Nucleus Accumbens Core prevents the increase in anxiety following ...
Willow Clayton +9 more
wiley +1 more source
The role of mycotoxins in pig reproduction : a review [PDF]
, 2009 Mycotoxins are commonly present in feed for farm animals. Sows and gilts are highly susceptible to mycotoxins. This article presents a review describing the main mycotoxins encountered in pig feed which have a negative impact on sow fertility and ...
Kanora, Alain, Maes, Dominiek
core
Implant strategies for finishing calves [PDF]
, 1996 Two hundred-sixteen Angus and Angus-cross steer calves (690 lb) were used in a 129- day finishing study to evaluate different implant strategies, including an experimental new implant for feedlot cattle that contains 28 mg of estradiol benzoate and ...
Anderson, P.T. +3 more
core +2 more sources
Ovarian response of Suffolk ewes to estrous synchronization using short-term protocol
Revista Brasileira de Zootecnia, 2012 The efficacy of estrus synchronization using short-term protocol was evaluated by ultrasound exams in Suffolk ewes during the pre-breeding season. The control Group (n = 12) was synchronized by treatment for 12 days with vaginal sponges impregnated with ...
Luciana Takada +5 more
doaj +1 more source