Results 261 to 270 of about 484,589 (309)
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Estrogen Receptors and Anti-Estrogen Therapies
2006The realisation that breast cancer growth is regulated by the hormone estrogen led to the development of tamoxifen as the first target-directed cancer drug. Clearly, there is considerable headway to be made in further elucidating estrogen receptor function, in particular in identifying the mechanisms underlying endocrine resistance.
Lakjaya, Buluwela +3 more
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Estrogen, Anti‐Estrogen, and Gender
Annals of the New York Academy of Sciences, 2002Abstract:In Part 1 of this report, we review data on the effects of estrogen (E), the anti‐E tamoxifen (TMX), and testosterone (T) on methamphetamine (METH)‐induced neurotoxicity in female and male CD‐1 mice. Treatment of gonadectomized females with a physiological regimen of E significantly diminished the amount of striatal dopamine (DA) depletion to ...
Dean E, Dluzen, Janet L, McDermott
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Heterogeneity of Estrogen Binding Sites: Relationship to Estrogen Receptors and Estrogen Responses
1980Publisher Summary This chapter discusses the significance of the various forms of estrogen binding sites. Estrogen receptors are macromolecules that bind estrogen to form receptor hormone complexes. These complexes are generally involved with the stimulation of cellular growth and metabolism.
J H, Clark +5 more
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European Journal of Obstetrics & Gynecology and Reproductive Biology, 1997
The aim of the present study was to evaluate the estrogen dermatitis of women who have chronic skin disorders with exacerbations or premenstrual dermatitis in a cyclic pattern. Twenty-three women exhibiting skin disorders of pruritus, urticaria, eczema, papulovesicular eruption, hirsutism-acne with hyperpigmentation (hirsutism and/or its related ...
Leylek, OA +5 more
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The aim of the present study was to evaluate the estrogen dermatitis of women who have chronic skin disorders with exacerbations or premenstrual dermatitis in a cyclic pattern. Twenty-three women exhibiting skin disorders of pruritus, urticaria, eczema, papulovesicular eruption, hirsutism-acne with hyperpigmentation (hirsutism and/or its related ...
Leylek, OA +5 more
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Estrogen as an immunomodulator
Clinical Immunology, 2004Estrogen's role in the sex differences observed in autoimmune diseases such as systemic lupus, multiple sclerosis, and rheumatoid arthritis have remained unclear. Complicating the understanding of the immunomodulatory effects of estrogen are (1) the effects of estrogen on multiple components of the immune response; (2) its varied effects on different ...
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Journal of the American Academy of Dermatology, 1995
Autoimmune progesterone dermatitis includes pruritus, urticaria, papulovesicular eruptions, and bullous erythema multiforme. Sensitivity to estrogen has not been described, although it was probably first recognized almost 50 years ago.Our purpose was to assess sensitization to selected hormones in women with a significant premenstrual flare of skin ...
W B, Shelley +3 more
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Autoimmune progesterone dermatitis includes pruritus, urticaria, papulovesicular eruptions, and bullous erythema multiforme. Sensitivity to estrogen has not been described, although it was probably first recognized almost 50 years ago.Our purpose was to assess sensitization to selected hormones in women with a significant premenstrual flare of skin ...
W B, Shelley +3 more
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New England Journal of Medicine, 1969
In the article by Dr. Joseph Rogers "Estrogens in the Menopause and Postmenopause" publish in the February 13 issue of the Journal he summarily dismisses the problem of estrogens and carcinoma with one sentence and a reference to a 15 year old paper (Obst. & Gynec.
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In the article by Dr. Joseph Rogers "Estrogens in the Menopause and Postmenopause" publish in the February 13 issue of the Journal he summarily dismisses the problem of estrogens and carcinoma with one sentence and a reference to a 15 year old paper (Obst. & Gynec.
openaire +2 more sources
Estrogen and Neurodegeneration
Neurochemical Research, 2003Although estrogen is best known for its effects on the maturation and differentiation of the primary and secondary sex organs, increasing evidence suggests that its influence extends beyond this system, and its activity in the CNS may initiate, or influence our susceptibility to neurodegenerative decline.
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Hastings Center Report, 2013
AbstractEvery so often, a bioethics controversy emerges that galvanizes our views. The Surfactant, Positive Pressure, and Oxygenation Randomized Trial mushroomed into a controversy of this sort this past year. In 2007, the “Ashley case,” involving the use of estrogen to attenuate the growth of a girl with profound disabilities, was similarly ...
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AbstractEvery so often, a bioethics controversy emerges that galvanizes our views. The Surfactant, Positive Pressure, and Oxygenation Randomized Trial mushroomed into a controversy of this sort this past year. In 2007, the “Ashley case,” involving the use of estrogen to attenuate the growth of a girl with profound disabilities, was similarly ...
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The Pharmacology of the Estrogens
Annual Review of Pharmacology, 1971This review of the pharmacology of estrogens briefly discusses the metabolism of estrogens with respect to biogenesis catabolic pathways and conjugation of estrogen metabolites. The metabolism of estrogens in the fetoplacental unit is also discussed. The secretion of estrogens including the effect of estrogen in the intact animal effects of estrogens
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