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Estrogens and Arthritis

Rheumatic Disease Clinics of North America, 2005
Sex hormones seem to play an important role as modulators and perpetuators of rheumatic disorders with autoimmune involvement, such as rheumatoid arthritis or systemic lupus erythematosus. Estrogens are implicated in the immune response as enhancers of the humoral immunity.
Robert G. Lahita   +2 more
openaire   +4 more sources

Enzymatic treatment of estrogens and estrogen glucuronide

Journal of Environmental Sciences, 2009
Natural and synthetic estrogens from sewage treatment systems are suspected to influence the reproductive health of the animals in the rivers. In this article, we investigated the enzymatic treatment of three estrogens (estrone, 17beta-estradiol, and 17alpha-ethynyletstradiol) by a fungal laccase which oxidize phenolic compounds with dissolved oxygen ...
Tomokazu Kawase   +6 more
openaire   +3 more sources

Pharmacokinetics of estrogen

International Journal of Gynecology & Obstetrics, 1990
The main types of pharmacologic therapy used to treat the hormone deficiency of menopause are parenteral and oral administrations of estrogen. Parenteral administration results in predictable absorption without major intermediary metabolism, whereas all oral estrogens are subject to intestinal metabolism before entering the systemic circulation ...
openaire   +2 more sources

Biological Role of Estrogen and Estrogen Receptors

Critical Reviews in Biochemistry and Molecular Biology, 2002
(2002). Biological Role of Estrogen and Estrogen Receptors. Critical Reviews in Biochemistry and Molecular Biology: Vol. 37, No. 1, pp. 1-28.
Jan-Åke Gustafsson, Stefan Nilsson
openaire   +3 more sources

Estrogen and Neurodegeneration

Neurochemical Research, 2003
Although estrogen is best known for its effects on the maturation and differentiation of the primary and secondary sex organs, increasing evidence suggests that its influence extends beyond this system, and its activity in the CNS may initiate, or influence our susceptibility to neurodegenerative decline.
openaire   +2 more sources

Estrogen and estrogen receptors of breast cancer

Journal of Surgical Oncology, 1975
AbstractHuman breast cancer can be divided into a group that contains specific receptor sites for estrogen and a group without such specific estrogen‐binding sites. The presence of specific estrogen receptors in some tumors indicating hormonal dependency has been shown to be of predictive value for endocrine treatment.
Howard H. Sky-Peck   +3 more
openaire   +3 more sources

Estrogens and Menopause

JAMA: The Journal of the American Medical Association, 1976
RECENT reports suggest that the administration of estrogens to postmenopausal women is associated with an increased risk of acquiring endometrial cancer. The problem was identified in retrospective studies in which postmenopausal patients with endometrial cancer were compared to matched controls with respect to their history of estrogen therapy.
openaire   +4 more sources

Estrogen Receptors and Anti-Estrogen Therapies

2006
The realisation that breast cancer growth is regulated by the hormone estrogen led to the development of tamoxifen as the first target-directed cancer drug. Clearly, there is considerable headway to be made in further elucidating estrogen receptor function, in particular in identifying the mechanisms underlying endocrine resistance.
Simak Ali   +3 more
openaire   +3 more sources

A Good Estrogen

Science, 1998
Robert Service's article “New role for estrogens in cancer?” (Research News, 13 Mar., [p. 1631][1]) reminds us of the dark side of estrogen metabolites in promoting cancers. However, a major estrogen metabolite, 2-methoxyestradiol (2ME2), represents the bright side of the story.
Shawn J. Green, Victor S. Pribluda
openaire   +3 more sources

Estrogens and the heart

American Journal of Obstetrics and Gynecology, 1967
Abstract The effects of estrogen on the function of the in situ canine heart muscle cell was investigated. After 40 mg. of Premarin was administered intravenously, no significant changes in the surface and intracellular electrographs were found. There were no differences in the electrography obtained from male and from female dogs.
Kazuo Ishikawa   +13 more
openaire   +3 more sources

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