Results 161 to 170 of about 138,106 (224)

Addressing Sex as a Biological Variable in Preclinical Models of Lung Disease: An Official American Thoracic Society Research Statement. [PDF]

Am J Respir Crit Care Med
Lingappan K, Sundar IK, Prakash YS, Redente EF, Sin DD, Han MK, Lahm T, Krymskaya VP, Kotton DN, Kulkarni HS, Jain R, Königshoff M, Eghbali M, Anguera M, Arnold A, Silveyra P, DeMeo DL.   +16 more
europepmc   +1 more source

Exploring Fall-Related Fracture Risk by Possible Fall-Risk Increasing Drugs in Japanese Older Adults Using Municipal Linked Medical and Long-Term Care Claim Data: A Nested Case-Control and Case-Crossover Study. [PDF]

Geriatr Gerontol Int
Nakano H, Iwagami M, Komiyama J, Sun Y, Hamasaki Y, Taniguchi Y, Kuroda N, Suzuki A, Tamiya N.   +8 more
europepmc   +1 more source

Histochemical evaluation of estrogenic and antiestrogenic properties of some non-steroidal post-coital antifertility agents.

The Indian journal of medical research, 1975
N K, Sud, B S, Setty
openaire   +1 more source

Profile of steroid metabolites in human breast milk in different stages of lactation.

Food Funct
Khymenets O, Vilarroya O, Benet G, Feixas G, Arranz Betegon A, McLeod MD, Pozo OJ.   +6 more
europepmc   +1 more source

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Non-Steroidal Subtype Selective Estrogens

Current Medicinal Chemistry, 2005
The biological effects of estrogens are thought to be mediated by two receptors referred to as ERalpha and ERbeta. In recent years significant efforts have been devoted to the design of subtype selective ligands. These ligands are valuable tools to establish the precise biological role of each of the subtypes and to develop new generations of ...
G. Veeneman
openaire   +3 more sources

Estrogenic diazenes: heterocyclic non-steroidal estrogens of unusual structure with selectivity for estrogen receptor subtypes

Bioorganic & Medicinal Chemistry, 2003
Estrogens regulate many biological functions, often acting in a tissue-selective manner. Their tissue-selective action is believed to involve differential estrogen action through the two estrogen receptor (ER) subtypes, ERalpha and ERbeta, as well as differential interaction of the ligand-receptor complexes with promoters and coregulator proteins.
Usha, Ghosh, Deshanie, Ganessunker, Viswajanani J, Sattigeri, Kathryn E, Carlson, Deborah J, Mortensen, Benita S, Katzenellenbogen, John A, Katzenellenbogen   +6 more
openaire   +3 more sources

Transcriptional regulation of estrogen-responsive genes by non-steroidal estrogens: Doisynolic and allenolic acids

The Journal of Steroid Biochemistry and Molecular Biology, 1997
Estrogen receptor (ER), a member of the nuclear receptor superfamily, exerts prominent physiological roles in both humans and other species by acting directly as a transcription factor, altering nuclear gene expression. One peculiarity of estrogenic regulation is that it is affected by a wide variety of non-steroidal compounds in addition to the ...
C Y, Meyers, H G, Lutfi, S, Adler
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Non-steroidal Estrogens

1999
Endogenous estrogens, such as 17β-estradiol (1, Scheme 1), have long been recognized as the primary hormones involved in the development and maintenance of the female sex organs, mammary glands and other sexual characteristics. More recently, their involvement in the growth and/or function of a number of other tissues, such as the skeleton, the ...
J. A. Dodge, C. D. Jones
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Experimental electron density studies of non-steroidal synthetic estrogens: Diethylstilbestrol and dienestrol

Journal of Molecular Structure, 2008
Abstract An experimental charge density analysis has been carried out on two synthetic estrogens, diethylstilbestrol (DES) and dienestrol (DNS), to further investigate the alignment and binding of estrogenic compounds to the estrogen receptor, and to also establish a relationship between the biological function and the electronic properties of ...
Eric J. Yearley, Elizabeth A. Zhurova, Vladimir V. Zhurov, A. Alan Pinkerton   +3 more
openaire   +2 more sources