Results 111 to 120 of about 91,779 (299)
Advanced Science, EarlyView.CAF‐derived exosomes deliver circFAD104 into TNBC cells, where it acts as a molecular scaffold that bridges the E3 ligase MARCHF8 and PGM1, promoting MARCHF8‐mediated K48‐linked ubiquitination and proteasomal degradation of PGM1. Loss of PGM1 redirects glucose‐phosphate flux from glycogen synthesis toward glycolysis, thereby driving stemness, EMT, and ...
Lei Wang +16 more
wiley +1 more source
Human Exposure to Medical, Dietary, and Environmental Estrogens
, 2007 Estrogens are a broad class of compounds which exert many physiological effects. in addition to gonadal and peripheral endogenous estrogen production, humans can be exposed to exogenous estrogenic compounds (xenoestrogens) from medicinal, dietary and ...
Hunter, Loretta D. +2 more
core +1 more source
Advanced Science, EarlyView.The injectable CeTA@GPP hydrogel is administered via intrauterine injection, forming a protective barrier. In the high ROS inflammatory microenvironment of injured endometrium, boronate ester cleavage triggers responsive CeTA release and local enrichment.
Peixian Cheng +8 more
wiley +1 more source
New routes to A-ring substituted estrogens
, 1983 Estrogens can be regiospecifically functionalized at the position 2 by a few electrophilic reagents. Reactions of estradiol 3-methyl ether-17 beta-acetate with Hg(OAc)2 and BF3 .
E. Santaniello, P. Ferraboschi
core +1 more source
Advanced Science, EarlyView.TNFRSF19 is an epigenetically silenced regulator of mitophagy in triple‐negative breast cancer. TNFRSF19 deficiency activates the TGFBR1–SMAD3–PINK1 axis to promote mitophagy and confer doxorubicin resistance, whereas decitabine‐mediated restoration of TNFRSF19 suppresses mitophagy and enhances doxorubicin sensitivity, revealing a targetable epigenetic–
Shiyang Liu +7 more
wiley +1 more source
Advanced Science, EarlyView.Combined structure‐function assessment in aortic rings from Marfan mice using MechaMorph Opto‐Biomechatronics technology relates increased elasticity (stiffness) and dynamic viscosity and less ordered extracellular matrix 3D‐structure (collagen) as potential causes for impaired Windkessel function and compromised haemodynamics in Marfan's syndrome ...
Dominik Schneidereit +10 more
wiley +1 more source
Cosmetics and More Handout, Environmental Estrogens in Everyday Products
, 2009 Handout on environmental estrogens in cosmeticsThis handout provides information on what you can do now to recognize ingredients in cosmetics that are environmental estrogens, and what you can do to reduce your exposure.
Snedeker, Suzanne M., Stone, Heather M.
core +3 more sources
Modification of blood pressure in postmenopausal women: role of hormone replacement therapy
International Journal of Women's Health, 2014 Marianna Cannoletta, Angelo Cagnacci Institute of Obstetrics and Gynecology, Department of Medical and Surgical Sciences of the Mother, Child and Adult, University of Modena and Reggio Emilia, Modena and Reggio Emilia, Emilia-Romagna, Italy Abstract ...
Cannoletta M, Cagnacci A
doaj
Impact of environmental estrogens on Yfish considering the diversity of estrogen signaling.
, 2013 Research on endocrine disruption in fish has been dominated by studies on estrogen-active compounds which act as mimics of the natural estrogen, 17β-estradiol (E2), and generally exert their biological actions by binding to and activation of estrogen ...
Segner, Helmut +12 more
core +1 more source
Advanced Science, EarlyView.A sono‐responsive chemo‐immune checkpoint nanoinhibitor (Sono‐TT8) co‐delivering TPZ chemotherapy and siXkr8 simultaneously kills tumor cells and blocks PS externalization, reversing chemotherapy‐induced immunosuppression and enhancing antitumor immunity. ABSTRACT Breast cancer features an immunosuppressive tumor microenvironment following chemotherapy
Yunfan Liu +13 more
wiley +1 more source