Results 111 to 120 of about 82,387 (308)
, 2001 Estrogens and testosterone declines with aging and serum estradiol remains higher in older men than in ...
ZIRILLI, Lucia +4 more
core
Selenium‐Based Nanoplatforms: An Emerging Theranostic Paradigm for Gynecological Cancers
Advanced Science, EarlyView.This reivew summarizes Selenium as a multifunctional anticancer regulator in gynecological cancers. It reduces tumor risk, enhances therapeutic efficacy, and reduces treatment toxicity. Selenium also overcomes chemoraditherapy resistance, improving overall treatment outcomes. ABSTRACT Gynecological cancers present significant therapeutic challenges due
Hejing Liu +9 more
wiley +1 more source
Estrogens of multiple classes and their role in mental health disease mechanisms
, 2010 Cheryl S Watson1, Rebecca A Alyea1, Kathryn A Cunningham2, Yow-Jiun Jeng11Department of Biochemistry and Molecular Biology, 2Department of Pharmacology and Toxicology, Univ of Texas Medical Branch, Galveston, TX, USAAbstract: Gender and sex hormones can ...
Cheryl S Watson +3 more
core
Advanced Science, EarlyView.NET‐DNA is enriched during early endometriotic lesion establishment and drives anoikis resistance by promoting an ANXA2–TMEM215–BiP axis. This pathway strengthens ER–mitochondria contacts, enhances PINK1/Parkin‐associated mitophagy, preserves mitochondrial homeostasis, and supports ectopic stromal cell survival, thereby facilitating lesion persistence ...
Honglin Wang +12 more
wiley +1 more source
Estrogens and the G protein-coupled estrogen receptor in prostate cancer: angels or demons?
, 2023 Prostate cancer (PCa) is the second most frequent type of cancer among men, with an increasing incidence worldwide. PCa is highly regulated by hormones, with androgens playing a crucial role in its development and progression. However, also estrogens are
Figueira, Marília Isabel Neto
core
CK2α Deficiency Drives Myocardial Fibrosis via Desmin‐Induced Mitochondrial Dysfunction
Advanced Science, EarlyView.CK2α preserves mitochondrial homeostasis by phosphorylating Desmin to recruit Cryab, ensuring proper filament assembly. CK2α deficiency disrupts this interaction, causing mitochondrial dysfunction, metabolic shifts, bioenergetic failure, and oxidative stress—ultimately establishing a pro‐fibrotic environment that drives cardiac fibrosis.
Canjie Ma +12 more
wiley +1 more source
Estrogens and the hair follicle
, 2004 While it is undisputed that estrogens (1 beta-estradiol, E2) are mainly involved in skin physiology and operate as potent hair growth modulators, our knowledge about the estrogen target cells in skin and exact signaling pathways is still very limited ...
Paus, Ralf, Conrad, Franziska
core +1 more source
Advanced Science, EarlyView.STAID is a unified deep learning framework that couples iterative pseudo‐spot refinement with neural network training through a feedback loop and exploits gene co‐expression information to model higher‐order interactions, achieving accurate and robust cell‐type deconvolution in spatial transcriptomics.
Jixin Liu +5 more
wiley +1 more source
Modification of blood pressure in postmenopausal women: role of hormone replacement therapy
International Journal of Women's Health, 2014 Marianna Cannoletta, Angelo Cagnacci Institute of Obstetrics and Gynecology, Department of Medical and Surgical Sciences of the Mother, Child and Adult, University of Modena and Reggio Emilia, Modena and Reggio Emilia, Emilia-Romagna, Italy Abstract ...
Cannoletta M, Cagnacci A
doaj
Advanced Science, EarlyView.Triple‐negative breast cancer (TNBC) cells evade natural killer (NK) cell immunity by secreting IL8 and CXCL1. These chemokines suppress NK cells’ function via CXCR1/2 and enhance cancer cells’ survival through PD‐L1 upregulation and BCL‐2 anti‐apoptotic signaling.
Mingheng Yuan +6 more
wiley +1 more source