Results 191 to 200 of about 239,432 (343)

Macrophagic Sclerostin Loop2‐ApoER2 Interaction Required by Sclerostin for Cardiovascular Protective Action

Advanced Science, EarlyView.
Sclerostin loop2‐ApoER2 interaction in macrophages is required by sclerostin to suppress NF‐κB nuclear translocation and phosphorylation, to promote macrophage conversion into anti‐inflammatory subtypes in atherosclerotic aortas, as well as to prevent atherosclerosis and aortic aneurysm development in ApoE−/− mice. Abstract Therapeutic antibody against
Luyao Wang, Xiaohui Tao, Ning Zhang, Xin Yang, Hewen Jiang, Xiaofei Li, Shenghang Wang, Shijian Ding, Sifan Yu, Huarui Zhang, Yihao Zhang, Nanxi Li, Haitian Li, Zhanghao Li, Xiaoxin Wen, Meiheng Sun, Chuanxin Zhong, Jin Liu, Yuanyuan Yu, Xianghang Luo, Tao Zhang, Shu Zhang, Péter Ferdinandy, Yu Huang, Daqing Ma, Aiping Lu, Baoting Zhang, Ge Zhang   +27 more
wiley   +1 more source

Long‐term prognosis is associated with residual disease after neoadjuvant systemic therapy but not with initial nodal status

BJS (British Journal of Surgery), EarlyView., 2020
This long‐term follow‐up study determined survival rates in a Swedish national cohort of 417 patients with breast cancer who all had neoadjuvant systemic therapy (NAST). Sentinel lymph node biopsy (SLNB) was performed before NAST in clinically node‐negative and after NAST in clinically node‐positive patients.
L. Zetterlund, F. Celebioglu, T. Hatschek, J. Frisell, J. de Boniface   +4 more
wiley   +1 more source

The testobolome in microbial testosterone metabolism and human health. [PDF]

NPJ Biofilms Microbiomes
Veerus L, Subrahmanian A, Blaser MJ.
europepmc   +1 more source

CD147/Basigin: From Integrative Molecular Hub to Translational Therapeutic Target

Advanced Science, EarlyView.
This review conceptualizes CD147 as a fundamental “Energy‐Structure Coupler,” physically bridging metabolic flux (via MCTs) with morphogenetic plasticity (via integrins/MMPs) to drive cancer, infection, and autoimmunity. Addressing the “specificity paradox” that limits current translation, the authors chart a strategic roadmap—spanning logic‐gated ...
Xiang‐Min Yang, Huijie Bian, Zhi‐Nan Chen   +2 more
wiley   +1 more source

Reply to Urbina, F. Are Estrogens Involved in the Earlier Onset of Psoriasis in Girls? Comment on "Cassalia et al. How Hormonal Balance Changes Lives in Women with Psoriasis. <i>J. Clin. Med.</i> 2025, <i>14</i>, 582". [PDF]

J Clin Med
Cassalia F, Lunardon A, Frattin G, Danese A, Caroppo F, Belloni Fortina A.   +5 more
europepmc   +1 more source

Biomimetic Membrane Interface Technologies for Detection and Isolation of CTCs and EVs: Advances and Opportunities in Liquid Biopsy

Advanced Science, EarlyView.
Biomimetic membrane interface engineering constructs functionalized detection platforms by integrating natural cell membranes, synthetic lipids, or hybrid membranes. This strategy effectively reduces background interference and enables efficient target capture and analysis, showing broad applications in circulating tumor cell separation, extracellular ...
Duo Liu, Jie Yu, Jingxue Li, Yixue Chen, Mengle Peng, Yifan Xu, Yongjun Wu, Lihua Ding, Sitian He   +8 more
wiley   +1 more source

A Systematic Review of Estrogens as Emerging Contaminants in Water: A Global Overview Study from the One Health Perspective. [PDF]

J Xenobiot
da Silva RL, Lima E Silva MA, Teixeira TP, Farnesi de Assunção TS, Teixeira PP, Tamagno WA, Rocha TL, Gonçalves JCSI, Marcon M.   +8 more
europepmc   +1 more source

Bioavailability of Isoflavone Metabolites After Korean Fermented Soybean Paste ( Doenjang ) Ingestion in Estrogen‐Deficient Rats [PDF]

, 2018
Da‐Hye Lee, Min Jung Kim, So‐Hyun Park, Eun‐Ji Song, Yong‐Do Nam, Jiyun Ahn, Young Jin Jang, Tae Youl Ha, Chang Hwa Jung   +8 more
openalex   +1 more source

“Time Is Brain” – for Cell Therapies

Advanced Science, EarlyView.
The concept that “time is brain” extends to stem cell therapy for stroke. Evidence across preclinical and clinical studies indicates that delivery timing shapes graft survival, integration, and efficacy by matching the evolving post‐stroke microenvironment.
Hao Yin, Dominikus Brian, Rebecca Z. Weber, Patrick D. Lyden, Ruslan Rust   +4 more
wiley   +1 more source

Diversity of estrogen biodegradation pathways and application in environmental bioremediation. [PDF]

Front Microbiol
Hashem JS, Ismail W, Chiang YR, Bekhit AA.   +3 more
europepmc   +1 more source