Results 211 to 220 of about 91,779 (299)

Estrogens and the Liver

Gastroenterology, 1967
openaire   +2 more sources

Lipid droplet profiling during neutrophil differentiation by stimulated Raman scattering microscopy

Biotechnology Progress, EarlyView.
Abstract Lipid droplets (LDs) are dynamic organelles that serve as metabolic hubs and emerging regulators of immune cell fate. Although LDs have been implicated in immune regulation, how LD metabolism is remodeled during neutrophil differentiation and how stage‐specific LD dynamics shape mature neutrophil function remain poorly defined.
Ting‐Jung Sung, Bin Dong, Jingqiao Shen, Yan Tan, Chi Zhang, Xiaoping Bao   +5 more
wiley   +1 more source

Mapping of sex hormones in the testicular vein of healthy men.

J Clin Endocrinol Metab
Hufnagel A, Frederiksen H, Albrethsen J, Johannsen TH, Juul A, Jensen RJ, Rehfeld A, Barrès R.   +7 more
europepmc   +1 more source

Industrialization increases the estrogen-recycling capacity of the gut microbiome. [PDF]

Proc Natl Acad Sci U S A
Brittain RSA, Bribiescas RG, Jasienska G.   +2 more
europepmc   +1 more source

Rapid and Reusable Amino Acid–Derived MOFs for the Removal of Estrogenic Hormones From Real Water Matrices

Chemistry – A European Journal, EarlyView.
A family of amino‐acid–derived MOFs enables ultrafast (>90–95% in 30 s) simultaneous removal of four estrogenic contaminants from water under SPE conditions. A leucine‐based MOF shows excellent regenerability and robustness in real samples, with structural evidence revealing efficient hormone encapsulation.
Lidia García, Alejandro Cortés‐Villena, Héctor Martínez Pérez‐Cejuela, José Manuel Herrero‐Martínez, Jesús Ferrando‐Soria, Thais Grancha, Donatella Armentano, Emilio Pardo   +7 more
wiley   +1 more source

Increased Insulin Action, Glucose Metabolism and Muscle Function in Supervillin‐Knockout and Supervillin‐Mutant Mice

Cytoskeleton, EarlyView.
ABSTRACT We here describe mouse models with complementary homozygous Svil mutations. In skeletal muscle, Svil‐Mut mice express the Svil‐encoded N‐terminus fused to the βgal‐neo gene‐trap tag and lack the highly conserved archvillin C‐terminus; Svil‐KO mice lack expression of all known Svil‐encoded proteins; and Svil‐LoxP mice contain loxP sites for ...
Tara C. Smith, Lauren A. Tauer, Randall H. Friedline, Xiaodi Hu, Duy Tran, Yangyi E. Luo, Nacima Hadjout‐Rabi, Elisabeth R. Barton, Jason K. Kim, Elizabeth J. Luna   +9 more
wiley   +1 more source

More than alternative estrogen receptors: the emerging role of GPER-1 and ERα36 in breast cancer. [PDF]

Explor Target Antitumor Ther
Molina Calistro L, Torres RF, Spies J, Meneses SS, Soto M, Carrasco J, Gálvez J, Muñoz D, Soto J, Arancibia Y.   +9 more
europepmc   +1 more source

Biography as the Missing Variable in Drug Development: A Case for Bio‐Biographical Mechanistic Profiling

Clinical Pharmacology &Therapeutics, EarlyView.
Most clinical trial failures reflect unmeasured biological heterogeneity. Biography — chronic stress, adversity, trauma, and social isolation—is a neglected source of that heterogeneity, operating through the same molecular pathways drugs engage.
Ralph I. Horwitz
wiley   +1 more source

Pathogenic mechanisms and comprehensive therapeutic strategies of ovarian aging: targeting gut microbiota. [PDF]

Front Microbiol
Chen Y, Tian S, Zeng J, Wu M, Tang P, Lei L, Liu W, Tang L.   +7 more
europepmc   +1 more source

Initiation of Gabapentin with Opioids and Risk of Respiratory Cardiovascular and Opioid‐Related Adverse Events Following Surgery for Breast Cancer

Clinical Pharmacology &Therapeutics, EarlyView.
Pain is a key determinant of quality‐of‐life following breast cancer surgery, the most common cancer operation in the United States. Gabapentinoids are frequently prescribed for pain management, yet their respiratory, cardiovascular, and opioid‐related adverse effects remain unclear.
Jyun‐Heng Lai, Anton L V Avanceña, Juan P Cata, Jamie C. Barner, Sharon H. Giordano, Chanhyun Park, Hui Zhao, Kirk E. Evoy, John K. Lin, Jennifer C. Spencer, Mariana Chavez‐MacGregor, Kelly K. Hunt, Kerollos Nashat Wanis   +12 more
wiley   +1 more source