Results 41 to 50 of about 68,964 (236)

Development and application of an UHPLC-MS/MS method for the simultaneous determination of 17 steroidal hormones in equine serum [PDF]

, 2017
A new, fast and simple analytical method that is able to identify and quantify simultaneously 17 steroid hormones and metabolites (Pregnenolone, 17-OH-Pregnenolone, Progesterone, 17-OH Progesterone, Androsterone, Androstenedione, DHEA, DHEAS ...
Allis, Bonfiglio, Büttler, Caron, Ceglarek, Goros, Guan, Huang, Kaabiaa, Kappas, Ke, Magnisali, Peitzsch, Ray, Schioler, Shao, Stanczyk, Taieb, Thomas, Wong, You   +20 more
core   +1 more source

Cysteine-10 on 17 β-Hydroxysteroid dehydrogenase 1 has stabilizing interactions in the cofactor binding region and renders sensitivity to sulfhydryl modifying chemicals [PDF]

, 2013
17 β-Hydroxysteroid dehydrogenase type 1 (17 β -HSD1) catalyzes the conversion of estrone to the potent estrogen estradiol. 17 β -HSD1 is highly expressed in breast and ovary tissues and represents a prognostic marker for the tumor progression and ...
Atanasov, Atanas G., Baker, Michael E., Nashev, Lyubomir G., Odermatt, Alex   +3 more
core   +3 more sources

A Receptor-Independent Effect of Estrone Sulfate on the hERG Channel

Journal of Pharmacological Sciences, 2009
We recently reported that physiological concentrations of 17β-estradiol partially down-regulate cardiac rapidly-activating delayed rectifier K+ currents (hERG currents) independently of estrogen-receptor signaling.
Shoko Kakusaka, Mahoko Asayama, Asami Kaihara, Tetsuo Sasano, Takeshi Suzuki, Junko Kurokawa, Tetsushi Furukawa   +6 more
doaj   +1 more source

Oleoyl-estrone is a precursor of an estrone-derived ponderostat signal [PDF]

The Journal of Steroid Biochemistry and Molecular Biology, 2011
Oleoyl-estrone (OE) is a powerful anti-obesity compound that decreases food intake, decreases insulin resistance and circulating cholesterol. OE stimulates a severe loss of body fat by decreasing adipose tissue lipid synthesis and maintaining lipolysis. Therefore, the body economy loses lipid energy because energy expenditure is maintained.
Vilà Pont, Ruth, Cabot, Cristina, Villarreal, Laura, Monegal, Ana, Ayet Galcerà, Eva, Romero Romero, María del Mar, Grasa Martínez, Maria del Mar, Esteve Ràfols, Montserrat, Fernández López, José Antonio, Remesar Betlloch, Xavier, Alemany, Marià, 1946-   +10 more
openaire   +3 more sources

Regenerating Rat Liver: Correlations Between Estrogen Receptor Localization and Deoxyribonucleic Acid Synthesis [PDF]

, 1984
Estrogen receptor activity was quantitated in the cytosol and nucleus of normal rat liver and in regenerating rat liver at several time intervals after 75% hepatectomy. Cytosolic estradiol binding in regenerating liver decreases at 12, 24, and 48 h after
Di Leo, A, Eagon, PK, Francavilla, A, Ove, P, Starzl, TE, Van Thiel, DH, Wu, SQ   +6 more
core   +1 more source

Voltammetric Determination of the Total Content of the Most Commonly Occurring Estrogens in Water Media

Molecules
Estrogens in aquatic environments pose significant ecological and health risks due to their cumulative effects rather than individual impacts. This study investigates the voltammetric behavior of estrone (E1), 17β-estradiol (E2), estriol (E3), and 17α ...
Jaromíra Chýlková, Jan Bartáček, Natálie Měchová, Miloš Sedlák, Jiří Váňa   +4 more
doaj   +1 more source

Study of Immobilization Procedure on Silver Nanolayers and Detection of Estrone with Diverged Beam Surface Plasmon Resonance (SPR) Imaging

Biosensors, 2013
An immobilization protocol was developed to attach receptors on smooth silver thin films. Dense and packed 11-mercaptoundecanoic acid (11-MUA) was used to avoid uncontrolled sulfidization and harmful oxidation of silver nanolayers.
Ibrahim Abdulhalim, Lev Tsapovsky, Robert S. Marks, Alina Karabchevsky   +3 more
doaj   +1 more source

A native bacterial consortium degrades estriol in domestic sewage and activated sludge via the 4,5-seco pathway and requires estriol to retain its biodegradation phenotype

Microbiology Spectrum
Estriol (E3) is one of the natural steroid estrogens commonly detected in wastewater. Although microbial biodegradation is a key process for removal of steroid estrogens during wastewater treatment, estriol biodegradation, and biotransformation ...
Jaleela S. Hashem, Wael Ismail, Yin-Ru Chiang, Vartul Sangal, Dorra Hentati, Nasser Abotalib, Adnan A. Bekhit   +6 more
doaj   +1 more source

Sex hormones in female residents of Yamal-Nenets autonomous district depending on the fertility status

Сибирский научный медицинский журнал, 2020
Severe climatic conditions adversely affect the human reproductive function; there is evidence of earlier aging of the endocrine system in residents of the northern territories.
A. E. Elfimova
doaj   +1 more source

Metabolic impact of endogenously produced estrogens by adipose tissue in females and males across the lifespan

Frontiers in Endocrinology
The aged population, expected to double by 2050, makes up a large proportion of people living with metabolic disease. Obesity rates in the elderly are rapidly increasing, with estimates that nearly 40% of men and women over the age of 60 are classified ...
Angel A. Lee, Angel A. Lee, Laura J. Den Hartigh, Laura J. Den Hartigh   +3 more
doaj   +1 more source