Results 91 to 100 of about 61,834 (330)

Cardamonin Commands the Colonic Metabolite Columbianetin Acetate to Compete Against LPS in Binding HMGB1 in the Kidney, Preventing Lipopolysaccharide‐Induced Renal Tubular Pyroptosis

Food Frontiers, EarlyView.
Cardamonin upregulate sd the intestinal metabolite columbianetin acetate, which competitively bound HMGB1 to prevent LPS‐induced renal tubular cell pyroptosis (the figure is created with BioRender). ABSTRACT Sepsis‐associated acute kidney injury (SA‐AKI) results in high mortality due to the lack of effective interventions. The current study reports the
Zihui Zhou, Xuechun Sun, Jian Zhou, Huali Meng, Pengfei Fan, Yufeng Chu, Hao Wu   +6 more
wiley   +1 more source

Pengaruh Ekstrak Daun Sirsak (Annona Muricata L.) terhadap Siklus Reproduksi pada Mencit Putih Dara [PDF]

, 1991
The effect of Annona muricata leaves extract on the estrous cycle was studied. Four treatments of this extract were caried out with 0%, 5%, 10% and 15% concentrations respectively.
Margawati, E. T. (E), Samsoedin, B. R. (B), Tappa, B. (B)   +2 more
core  

Selenium‐Containing Tea‐Derived Peptides Activate Alcohol Dehydrogenase and Ameliorate Alcohol‐Induced Liver Injury by Modulating Oxidative Stress Homeostasis

Food Frontiers, EarlyView.
The graphical abstract summarizes the experimental workflow: (1) Preparation of selenium‐containing tea‐derived peptides (TSE‐PP) guided by ADH activation; (2) Purification and LC‐MS/MS identification of selenium‐modified peptides; (3) Molecular docking to reveal peptide‐ADH interactions; (4) Evaluation of hangover‐alleviating and hepatoprotective ...
Lixia Zan, Wenyi Zhang, Ning Gao, Jing Fu, Wengang Jin, Xiaoning Zhao, Xinsheng Li, Tianli Yue   +7 more
wiley   +1 more source

Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP) Signaling in The Prefrontal Cortex Modulates Cued Fear Learning, But Not Spatial Working Memory, in Female Rats [PDF]

, 2018
A genetic polymorphism within the gene encoding the pituitary adenylate cyclase- activating polypeptide (PACAP) receptor type I (PAC1R) has recently been associated with hyper-reactivity to threat-related cues in women, but not men, with post-traumatic ...
Gilmartin, Marieke R., Herbst, Matthew R., Kirry, Adam J., Maskeri, Michelle M., Poirier, Sarah E., Rothwell, Amy C., Twining, Robert C.   +6 more
core   +1 more source

A review of the impact of micro‐ and nanoplastics on female reproduction: What we know and gaps in knowledge

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Micro‐and nanoplastics (MNPs) are breakdown products of plastics, and humans are exposed to these particles through air, water, food, and soil. There is a growing concern that human exposure to MNPs negatively impacts health. In this review we will discuss the potential health impact of MNPs on ovarian function and the hypothalamic–pituitary ...
Sanchayana Raghuvir, Shawn Alex, Deborah Clegg   +2 more
wiley   +1 more source

Recovery from Age-Related Infertility under Environmental Light-Dark Cycles Adjusted to the Intrinsic Circadian Period

Cell Reports, 2015
Female reproductive function changes during aging with the estrous cycle becoming more irregular during the transition to menopause. We found that intermittent shifts of the light-dark cycle disrupted regularity of estrous cycles in middle-aged female ...
Nana N. Takasu, Takahiro J. Nakamura, Isao T. Tokuda, Takeshi Todo, Gene D. Block, Wataru Nakamura   +5 more
doaj   +1 more source

An Evaluation of Oral Subchronic Toxicity of Maizinol (UP165), a Zea mays Leaf Extract

Journal of Applied Toxicology, EarlyView.
ABSTRACT Maize (Zea mays) has been consumed by humans for millennia and represents the third most abundant crop grown globally. Maize and maize‐derived products have a long history of safe consumption from bread and other cereal products in human diets worldwide. Aside from key dietary components like carbohydrates and proteins, the corn plant contains
J. Kyle Weston, Barry S. Lynch, James A. Akingbasote   +2 more
wiley   +1 more source

Follicular dynamics in Serrana goats [PDF]

, 2006
Twenty-two Serrana goats were studied through two successive estrous cycles in order to characterize their follicular dynamics during the breeding season. The ovaries of the goats were scanned daily by realtime ultrasonography and all follicles ≥3mm were
Almeida, José Carlos, Azevedo, Jorge Manuel Teixeira de, Baril, Gérard, Fontes, Paulo J., Mascarenhas, Ramiro, Simões, João, Valentim, Ramiro   +6 more
core   +1 more source

Fertility and Early Embryonic Development Toxicity of hzVSF‐v13 in Sprague–Dawley Rats

Journal of Applied Toxicology, EarlyView.
ABSTRACT Humanized virus suppressing factor–variant 13 (hzVSF‐v13), a monoclonal IgG4 antibody, is a potential therapeutic candidate for COVID‐19. Although fertility and embryonic developmental toxicity studies are crucial for the safety evaluation of new drugs, the toxicological profile of hzVSF‐v13 remains unexplored.
Ji‐Seong Jeong, Sang‐Yun Kim, Jinsoo Lee, Seung‐Jin Lee, Onju Ham, Woojin Kim, Wan‐Jung Im, Sungman Park, Kyong‐Cheol Ko, Jong‐Choon Kim, Yong‐Bum Kim   +10 more
wiley   +1 more source

Transepithelial electrical resistance (TEER): a functional parameter to monitor the quality of oviduct epithelial cells cultured on filter supports [PDF]

, 2015
Cultivation of oviduct epithelial cells on porous filters fosters in vivo-like morphology and functionality. However, due to the optical properties of the filter materials and the cells’ columnar shape, cell quality is hard to assess via light microscopy.
Chen, Shuai, Einspanier, Ralf, Schoen, Jennifer   +2 more
core   +2 more sources