Results 111 to 120 of about 30,379 (234)

Tannic Acid Mitigates Monosodium Glutamate‐Induced Cortical Damage by Modulating Synaptic and Calcium‐Related Gene and Protein Expression

Journal of Applied Toxicology, Volume 46, Issue 11, Page 4099-4111, November 2026.
ABSTRACT Neurotoxicity induced by excessive glutamatergic signaling is associated with synaptic dysfunction, calcium imbalance, and oxidative stress, which are key molecular events implicated in several neurodegenerative conditions. Monosodium glutamate (MSG), a common flavor enhancer, may exert neurotoxic effects, particularly on synaptic integrity ...
Medine Sibel Karagac, Enver Fehim Koçpinar, Hamid Ceylan   +2 more
wiley   +1 more source

Dose‐Related Gastric Toxicity of Diethyl Phthalate in Female Wistar Rats

Journal of Applied Toxicology, Volume 46, Issue 11, Page 4242-4254, November 2026.
ABSTRACT Diethyl phthalate (DEP) is commonly used in cosmetics, personal care products, and pharmaceutical formulations as a low‐molecular‐weight phthalate. Despite its widespread use, information on its effects on the gastric mucosa remains limited. This study examined the dose‐related effects of DEP on inflammation, oxidative stress, gastric mucosal ...
Gul Sahika Gokdemir, Mehmet Cihan Yavaş, Selim Demirtaş, Fazile Cantürk Tan, Salih Varol, Mehmet Tahir Gokdemir   +5 more
wiley   +1 more source

Hormonal Hinterlands: Mapping a Materialist Prehistory of Trans Medicine

Antipode, Volume 58, Issue 6, November 2026.
ABSTRACT This article reexamines social histories of sex hormones in relation to critical theories of trans embodiment. It aims to foreground the entanglement of medical transition's materials in the uneven development of space, labor, and value under racial capitalism.
Danny Foster
wiley   +1 more source

NR4A1‐Driven Granulosa Cell Ferroptosis Contributes to Obesity‐Related Ovarian Dysfunction and Metformin‐Mediated Ovarian Protection

The FASEB Journal, Volume 40, Issue 19, 15 October 2026.
Schematic illustrating that NR4A1‐driven granulosa cell ferroptosis mediates obesity‐related ovarian dysfunction, while metformin‐mediated ovarian protection is achieved via suppression of the PI3K/AKT–NR4A1 ferroptotic signaling cascade. ABSTRACT Obesity triggers ovarian dysfunction and female infertility accompanied by granulosa cell damage ...
Huihui Wang, Chaoying Wang, Shuaishuai Guo, Guang Yang, Junnan Fang, Jingyi Hu, Ran Jiang, Jun Zhai, Haixia Jin, Wenyan Song, Senlin Shi, Xianju Huang, Lin Qi, Zhaoting Wu, Yan Liu, Ning Song, Xiangyang Zhang, Guidong Yao   +17 more
wiley   +1 more source

Opposing Estrous Cycle-Dependent Norepinephrine and Dopamine Regulation in Response to Methamphetamine. [PDF]

J Neurochem
Bhimani RV, Pauly RC, Mietlicki-Baase EG, Park J.   +3 more
europepmc   +1 more source

Safe and Stable Germline Transmission of MSTN Mutations in Cattle

Animal Genetics, Volume 57, Issue 5, October 2026.
ABSTRACT With the global population expected to reach 10 billion by 2050, sustainable livestock production is critical. Gene editing of the myostatin (MSTN) gene represents a promising strategy to enhance muscle growth in cattle. In this study, MSTN‐mutated founder (F0) cows were used to generate F1 offspring via ovum pick‐up, in vitro fertilization ...
Gyeong‐Min Gim, Bae Young Choi, Jeongbin Yi, Kyeong‐Hyeon Eom, Soo‐Young Yum, Dae‐Jin Jung, Do‐Yoon Kim, Bokyoung Yang, Jong‐Seo Kim, Donghwan Shim, Goo Jang   +10 more
wiley   +1 more source

Effects of sexual dimorphism and estrous cycle on murine <i>Clostridioides difficile</i> infection. [PDF]

Infect Immun
Phan JR, Bacab E, Washington M, Niamba M, Do DM, Mata TV, Consul A, Blank L, Yang S, Howerton AJ, Heredia E, Soriano R, Consul M, Hassan-Casarez C, Leisgang Osse AM, Mugosa MRN, Kinney JW, Cross CL, Abel-Santos E.   +18 more
europepmc   +1 more source

On the importance of including both sexes in animal studies – insights from home‐cage monitoring

Biological Reviews, Volume 101, Issue 5, Page 2408-2426, October 2026.
ABSTRACT A review of behavioural studies using home‐cage monitoring (HCM) systems revealed that over 61% of studies used only male subjects, with only 24% including both sexes, despite evidence of substantial behavioural differences between male and female animals. This bias could influence the outcomes of biomedical research.
Maša Čater, Adam Dušek, Aleksandra Bartelik, Silvia Mandillo, Elisabetta Golini, Mara Rigamonti, Rasneer Sonia Bains, Hamish Forrest, Marion Rivalan, Melissa Long, Anna Kiryk, Lars Lewejohann, Nuno Henrique Franco   +12 more
wiley   +1 more source

Application of Machine Learning Models to Identify Differences in Neural Electrophysiological Properties Across Estrous Cycle Phases. [PDF]

Neuroinformatics
Raina A, Meitzen J.
europepmc   +1 more source

Network Pharmacology and In Vivo Evaluation of Modified Huanglian Wendan Decoction in Polycystic Ovary Syndrome With Insulin Resistance: Association With AGE–RAGE‐Related Signaling

Chemistry &Biodiversity, Volume 23, Issue 10, October 2026.
An integrated network pharmacology, chemical profiling, molecular docking, molecular dynamics, and in vivo strategy shows that Modified Huanglian Wendan Decoction improves reproductive and metabolic abnormalities in a rat model of PCOS with insulin resistance.
Xi Chen, Xing Yang, Xinni Wang, Dan Chou, Chenghong Zheng   +4 more
wiley   +1 more source