Results 31 to 40 of about 32,571 (297)

SIRT5–RAC2 Axis Drives Monocyte‐to‐Macrophage Differentiation to Promote Inflammatory Injury in Premature Ovarian Insufficiency

Advanced Science, EarlyView.
SIRT5 desuccinylates and stabilizes RAC2, activating CSF1R‐dependent signaling to drive monocyte differentiation into M0 macrophages and their polarization toward pro‐inflammatory M1 phenotypes in CTX‐induced premature ovarian insufficiency. Inhibiting the SIRT5‐RAC2 axis attenuates inflammation, reduces granulosa cell apoptosis, and preserves ...
Wenjing TanTai, Yaqi Li, Shengnan Liu, Minjuan Wu, Zhixiao Liu, Junfeng Jiang, Jingjing Chen, Xiaoding Xu, Li Li, Chaoqun Li, Fang Zhao, Ye Liu, Haitao Ni, Tengfei Zhang, Mingjuan Xu, Chaofeng Han   +15 more
wiley   +1 more source

Real‐Time and High‐Resolution NIR‐II‐L Imaging of Netrin‐1‐Mediated Neurovascular Coupling Driven by Dose‐Dependent Electroacupuncture

Advanced Science, EarlyView.
Disrupted neurovascular coupling contributes to ovarian dysfunction in polycystic ovary syndrome. Using near‑infrared II long‑wavelength imaging, this study visualizes how electroacupuncture dynamically regulates ovarian blood vessels in vivo. Immediate and cumulative stimulation elicit distinct vascular responses via a Netrin‐1 dependent mechanism ...
Yicong Wang, Zi‐Han Chen, Jiajia Li, Wei Hu, Ying Cao, Yu Wang, Xiaoyu Tong, Wenhan Lu, Yuze Yang, Yuehao Wang, Yan Xiao, Wenhao Gao, Yuning Chen, Yuyan Hou, Fan Zhang, Yi Feng   +15 more
wiley   +1 more source

The Effect of Alternating High-Sucrose and Sucrose Free-Diets, and Intermittent One-Day Fasting on the Estrous Cycle and Sex Hormones in Female Rats [PDF]

, 2022
Joanna Sadowska, Wioleta Dudzińska, Izabela Dziaduch   +2 more
openalex   +1 more source

Modeling chronic periodontitis in rats: Persistent alveolar bone loss mediated by periodontal pathogens

Animal Models and Experimental Medicine, EarlyView.
Irrigation of periodontal pockets with human periopathogens, in combination with a 14‐day ligature‐induced periodontitis protocol, significantly enhances alveolar bone loss and sustains bacterial colonization for up to 28 days following ligature removal, thereby more closely replicating the chronic nature of human periodontitis compared to the ligature
Maksym Skrypnyk, Chun Xu, Shlomo Berkovsky, Thilini Jayasinghe, Axel Spahr   +4 more
wiley   +1 more source

Chronic Stress Detrimentally Affects In Vivo Maturation in Rat Oocytes and Oocyte Viability at All Phases of the Estrous Cycle

Animals, 2021
Background: Stress has been considered as one of the causes of decreased reproductive function in women. However, direct evidence of the effect of chronic stress on oocytes depending on estrous cycle phases is limited.
Fahiel Casillas, Miguel Betancourt, Lizbeth Juárez-Rojas, Yvonne Ducolomb, Alma López, Alejandra Ávila-Quintero, Jimena Zamora, Mohammad Mehdi Ommati, Socorro Retana-Márquez   +8 more
doaj   +1 more source

Generating golden Syrian hamsters with conditional alleles via zygote microinjection of CRISPR/Cas9

Animal Models and Experimental Medicine, EarlyView.
We established the first conditional knockout (cKO) model in the golden Syrian hamster by CRISPR/Cas9‐mediated genome editing. Cas9 protein, two sgRNAs, and a donor plasmid carrying loxP‐flanked exon 2 of the ApoF gene were microinjected into one‐cell embryos. The floxed allele was efficiently generated (up to 27%) and transmitted through the germline.
Wei Chen, Xu Zhang, Rui Fan, Xia Li, Feifei Guan, Gefan Wan, Weining Kong, Xiaolong Qi, Shuo Pan, Sijing Shi, Yuanlong Su, Shan Gao, Wei Huang, Xunde Xian, Jiangning Liu, Yuhui Wang, Yuanwu Ma   +16 more
wiley   +1 more source

Dinamika Ovarium Selama Siklus Estrus pada Domba Garut (OVARIAN DYNAMIC DURING THE ESTROUS CYCLE IN GARUT EWES)

Jurnal Veteriner, 2014
Ovarian dynamics in the garut ewes had never been studied continuously by using ultrasonography.The aim of this study was to observe development of the follicles and corpus luteums in the estrous cyclein the garut ewes.
Satya Gunawan, Tuty Laswardi Yusuf, Mohamad Agus Setiadi, Arief Boediono, Rachmat Herman, Amrozi .   +5 more
doaj  

Changes in serum concentration of 17 beta-estradiol in female rats during estrous cycle after treatment with atrazine and zearalenone

Veterinární Medicína, 2001
A daily dose of 14 mg atrazine and 2.5 mg zearalenone, given p.o. during 5 days of estrous cycle to female rats, changed their estrous cycle in comparison with control animals.
M. Mitak, T. Gojmerac, B. Mandić, Ž. Cvetnić   +3 more
doaj   +1 more source

Unraveling ovarian histology: The key morphological aspects that spur the development of the Fossa ovarii in equine

The Anatomical Record, EarlyView.
Abstract The equine ovary exhibits unique structural and developmental features that distinguish it from those of other domestic species, including the presence of an ovulation fossa and an inversion of cortical and medullary layers. This study aimed to investigate the morphostructural development of the equine fetal ovary, with particular emphasis on ...
Laura Ver Goltz, Silvio Pires Gomes, Bruno Cesar Schimming, Fabio Cesar Magioli Abdala, Maria Angélica Miglino, Tais Harumi de Castro Sasahara   +5 more
wiley   +1 more source

Role of Peripheral Alpha2 Adrenergic Receptors in Tonic Pain During Different Stages of Estrous Cycle in Rats

Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd, 2007
Introduction: Estrogen and progesterone are supposed to modify pain sensitivity. However, the actual role of each of these steroid hormones in this respect is not well known.
AR Abyazi Shelmani, M Taherianfard
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