Results 31 to 40 of about 35,836 (303)

A multi-tissue transcriptomic landscape of female mice in estrus and diestrus provides clues for precision medicine

Frontiers in Cell and Developmental Biology, 2022
Female reproductive cycle, also known as menstrual cycle or estrous cycle in primate or non-primate mammals, respectively, dominates the reproductive processes in non-pregnant state.
Yiran Zhou, Yiran Zhou, Yiran Zhou, Han Yan, Wenjun Liu, Chengqing Hu, Yuan Zhou, Yuan Zhou, Ruya Sun, Ruya Sun, Yida Tang, Chao Zheng, Jichun Yang, Qinghua Cui, Qinghua Cui   +14 more
doaj   +1 more source

Females' estrous cycle parameters.

, 2013
Structure (data are presented in percentages of total cycles examined) (A); Intake (in grams) across the estrous cycle in LETO (B) and OLETF (C) females; feces estradiol (D) and progesterone (E) levels across the estrous cycle. Representative pictures of
Noga Kronfeld-Schor (210963), Mariana Schroeder (360122), Aron Weller (360129)   +2 more
core   +1 more source

Whole Transcriptome Analysis: Implication to Estrous Cycle Regulation

, 2021
Estrous cycle is one of the placental mammal characteristics after sexual maturity, including estrus stage (ES) and diestrus stage (DS). Estrous cycle is important in female physiology and its disorder may lead to diseases, such as polycystic ovary ...
Binyun Cao, Shaohua Yang, Zhanhang Wang, Yue Zhang, Xiaopeng An, Fu Li   +5 more
core   +1 more source

A Toolkit for Targeted Neuromodulation of Striatal Direct Pathway Neurons Rescues Parkinsonian Motor Deficits in Mice

Advanced Science, EarlyView.
An adeno‐associated virus (AAV) toolkit enables selective anatomical and functional targeting of striatal D1‐MSNs through retrograde transduction. Enhanced capsids and engineered enhancers drive robust transgene expression across murine and primate models.
Zexuan Hong, Yujing Zhang, Junjiao Zhang, Hanhe Liu, Qiwei Liu, Yanglei Li, Lixin Yang, Lixia Li, Zhongjie Liu, Zhen Yuan, Zhonghua Lu, Yefei Chen, Yuantao Li, Yuwu Jiang, Taian Liu   +14 more
wiley   +1 more source

Time Series Ovarian Transcriptome Analyses of the Porcine Estrous Cycle Reveals Gene Expression Changes during Steroid Metabolism and Corpus Luteum Development

Animals, 2022
The porcine estrous cycle is influenced by reproductive hormones, which affect porcine reproduction and result in physiological changes in the reproductive organs.
Yejee Park, Yoon-Been Park, Seok-Won Lim, Byeonghwi Lim, Jun-Mo Kim   +4 more
doaj   +1 more source

Mouse estrous cycle regulation of vaginal versus uterine cytokines, chemokines, α-/β-defensins and TLRs

, 2012
This study investigates the cyclic changes in innate immunity in the female reproductive tract (FRT) of mice during the estrous cycle. By examining uterine and vaginal tissues and secretions we show that innate immunity varies with the stage of the ...
Hickey, Danica K., Fahey, John V., Wira, Charles R.   +2 more
core   +1 more source

An Activity‐Dependent NEPAS–PTX3 Axis Links Neurovascular and Myelin Deficits to Cognitive Impairment

Advanced Science, EarlyView.
An activity‐dependent pathway links prefrontal circuit hypoactivity to cognitive impairment. Reduced PVA–mPFC activity upregulates NEPAS, which suppresses PTX3 secretion, leading to impaired angiogenesis, myelin deficits, and memory decline. Rescue is achieved by NEPAS knockdown or chemogenetic circuit activation.
Boya Hu, Zifei Chen, Bingmei Sun, Jiale Gao, Jiale Xu, Xiaochun Guo, Fenfei Gao, Zhongsi Wang, Jie Wu, Xiaoyu Ji, Peipei Liu, Bing Huang   +11 more
wiley   +1 more source

Regulation of the Estrous Cycle by Neutrophils via Opioid Peptides

, 2011
We found previously that neutrophil-depleted mice exhibited significant blockading of both the regular estrous cycle and cyclic changes of steroid hormone levels. In this study, we aimed at elucidation of the underlying mechanism.
Kisaburo Nagata, Yoshiro Kobayashi, Yutaka Tamaki, Soichiro Sasaki   +3 more
core   +1 more source

Fosl2 Regulates FSH‐Dependent Follicle Maturation Through Feedback Amplification of FSH/FSHR Signaling

Advanced Science, EarlyView.
This study identifies a FOSL2‐driven positive feedback loop that amplifies FSH/FSHR signaling. During FSH‐dependent follicle maturation, FSH induces Fosl2 expression via the cAMP‐PKA‐CREB cascade. FOSL2 in turn binds the promoters of Fshr and estrogen‐biosynthesis genes to enhance their transcription, thereby increasing Fshr mRNA level and amplifying ...
Hongru Shi, Chaoli Chen, Zaohong Ran, Jianning Liao, Zian Wu, Xiaodong Wang, Yongheng Zhao, Wenkai Ke, Bowen Tan, Yun Liu, Youqiang Su, Wei Ren, Xiang Li, Changjiu He   +13 more
wiley   +1 more source

Airway exposure to multi-walled carbon nanotubes disrupts the female reproductive cycle without affecting pregnancy outcomes in mice

Particle and Fibre Toxicology, 2017
Background The use of multiwalled carbon nanotubes (MWCNT) is increasing due to a growing use in a variety of products across several industries. Thus, occupational exposure is also of increasing concern, particularly since airway exposure to MWCNTs can ...
H. K. L. Johansson, J. S. Hansen, B. Elfving, S. P. Lund, Z. O. Kyjovska, S. Loft, K. K. Barfod, P. Jackson, U. Vogel, K. S. Hougaard   +9 more
doaj   +1 more source