Results 221 to 230 of about 41,399 (301)

Protein Tyrosine Phosphatase 1B‐Mediated Granulosa Cell Insulin Resistance Links Metabolic Stress to Aging‐Relevant Ovarian Dysfunction and Is Reversed by Gengnianchun

Aging Cell, Volume 25, Issue 6, June 2026.
Metabolic stress induces insulin resistance and upregulates PTP1B in granulosa cells, leading to aging‐relevant ovarian dysfunction. Gengnianchun (GNC) suppresses PTP1B, restores IRS1–AKT2–GLUT4 signaling, and preserves follicles, highlighting PTP1B as a therapeutic target for ovarian dysfunction in metabolically vulnerable states.
Yanqiu Rao, Ting Xu, Yan Ding, Jun Li, Lingyun Gao, Yun Wang, Wenjun Wang   +6 more
wiley   +1 more source

Hippocampal estrogen levels, receptor types, and epigenetics contribute to sex-specific memory vulnerabilities to concurrent acute stresses. [PDF]

Neuron
Hokenson RE, Rodríguez-Acevedo KL, Chen Y, Short AK, Samrari SA, Devireddy B, Jensen BJ, Winter JJ, Gall CM, Soma KK, Heller EA, Baram TZ.   +11 more
europepmc   +1 more source

Hormonal Treatment During Ex Vivo Lung Perfusion Ameliorates Brain Death Induced Inflammation

Artificial Organs, Volume 50, Issue 6, Page 866-876, June 2026.
Treatment of lungs during ex vivo perfusion with 17β‐estradiol and methylprednisolone improved graft quality. In females, treated and non‐treated groups presented reduced leukocyte infiltration and only the treatment improved perfusion flow. In males, treatment improved lung function by increasing compliance, paO2, and perfusion flow.
Marina Vidal‐dos‐Santos, Roberto Armstrong‐Jr, Fernanda Yamamoto Ricardo‐da‐Silva, Lucas Ferreira da Anunciação, Mayara Munhoz de Assis Ramos, Cristiano de Jesus Correia, Petra J. Ottens, Luiz Felipe Pinho Moreira, Henri G. D. Leuvenink, Ana Cristina Breithaupt‐Faloppa   +9 more
wiley   +1 more source

tVNS Mitigates Neuroinflammation and Nociception in a Rodent LPS Endotoxemia Model

Clinical and Translational Science, Volume 19, Issue 6, June 2026.
Experimental design and key findings. Four groups (Control+Sham, Control+tVNS, LPS+Sham, LPS+tVNS; n = 7 each) underwent serum ELISA, brain Western blot, and behavioral testing. tVNS altered serum Haptoglobin, IL‐6, CGRP1, and VE‐Cadherin levels, reversed LPS‐induced increases in brain IL‐1β, HMGB1, Haptoglobin, PAR‐2, and CGRP, and alleviated LPS ...
Kerem Atalar, Ece Alim, Aysen Calikusu, Elif Gulcicek Abbasoglu Topa, Hale Gok Dagidir, Meltem Bahcelioglu, Neslihan Bukan, Fusun Erten, Kazım Sahin, Saadet Özen Akarca Dizakar, Hayrunnisa Bolay   +10 more
wiley   +1 more source

First clinical use of the kisspeptin analog TAK-683 in the treatment of a follicular cyst in a goat: case report. [PDF]

Vet Res Commun
Uyanık G, Yüksel M, Kara F, Gözer A, Abay M.   +4 more
europepmc   +1 more source

Reactive Nitrogen–Dominant Plasma Accelerates Diabetic Wound Healing Through Regulated Angiogenesis and TGF‐β Normalisation

International Wound Journal, Volume 23, Issue 6, June 2026.
ABSTRACT Chronic diabetic wounds persist because of impaired angiogenesis, dysregulated transforming growth factor beta activity and delayed matrix remodelling. Non‐thermal atmospheric pressure plasma therapy represents a potential non‐pharmacologic approach to overcome these barriers.
Yu‐Pin Cheng, Tien‐Yang Chou‐Huang, Chih‐Chia Lee, Hua‐Lin Chen, Kuang‐Yao Cheng, Mu‐Chien Wu, Shih‐Sen Huang, Jiun‐Wen Guo, Jong‐Shinn Wu   +8 more
wiley   +1 more source

Cognitive neurobehavior and synaptic plasticity after vagus nerve stimulation in female rats: Interaction between estrous cycle and neurostimulation. [PDF]

Bioelectron Med
Olsen LK, Jones KA, Sharma B, Ethridge VT, Gargas NM, Cunningham SD, Rohan JG, Hatcher-Solis CN.   +7 more
europepmc   +1 more source

Potential Relationship Between YTHDF3 and CFTR in Myocardial Ischemia–Reperfusion Injury

Journal of Cellular and Molecular Medicine, Volume 30, Issue 11, June 2026.
ABSTRACT Myocardial ischemia–reperfusion injury (MIRI) is a common pathophysiological process in reperfusion therapy following myocardial infarction. It exacerbates myocardial damage and negatively impacts patient prognosis. This study aims to explore potential regulatory targets and related mechanisms in MIRI.
Baoxin Tang, Chenying Zhu, Heqing Wang, Mingkui Gao, Tieyan Li   +4 more
wiley   +1 more source

A Conformer-Based Time-Frequency Decoupling Network for Pig Vocalization Behavior Classification. [PDF]

Animals (Basel)
Wang J, Liu Y, Geng S, Wei F, Wu H, Song Y, Lv Y, Li S, Li Q.   +8 more
europepmc   +1 more source

Dynamic Transcriptomic Profiling of Mouse Endometrium Across the Estrous Cycle Reveals Phase‐Specific Regulatory Networks Underlying Cyclic Remodelling

Journal of Cellular and Molecular Medicine, Volume 30, Issue 12, June 2026.
ABSTRACT The mouse estrous cycle drives cyclical remodelling of the endometrium, essential for uterine function and embryo implantation. However, the molecular mechanisms orchestrating these dynamic changes remain incompletely defined. In this study, we preliminarily staged C57BL/6 mice using vaginal smear cytology and confirmed phase‐dependent ...
Xinyan Wang, Keyi Xu, Binting Li, Xiaotong Xu, Gang Lu, Le Wang, Ruolang Pan, Ting Zhang   +7 more
wiley   +1 more source