Results 41 to 50 of about 27,500 (174)

Handgrip and Acute Hemodynamic Responses During Cyclic Exercise: Randomized Clinical Trial

open access: yesThe Journal of Clinical Hypertension, Volume 28, Issue 6, June 2026.
ABSTRACT During exercise, fine hemodynamic adjustments are essential to ensure adequate energy supply. Although cyclic treadmill exercise has been widely studied, isometric exercise with Handgrip (HG) has gained relevance in conditioning and rehabilitation contexts, yet data on the acute hemodynamic effects of combining these modalities remain scarce ...
Marvyn de Santana do Sacramento   +7 more
wiley   +1 more source

EvDiscover - Sistematización del soporte a la gestión de estudios clínicos [PDF]

open access: yes, 2017
Este documento contiene la memoria del Trabajo de Fin de Grado que trata sobre la aplicación EvDiscover desarrollada por Ioritz Cabero Llama y tiene como objetivo obtener la titulación del Grado de Ingeniería Informática en la Facultad de Informática de ...
Cabero Llama, Ioritz
core  

Assessing D‐Squame as a Minimally Invasive Technique to Evaluate the Cutaneous Immune Response mRNA in a Dog Model of Canine Atopic Dermatitis

open access: yesVeterinary Dermatology, Volume 37, Issue 3, Page 353-364, June 2026.
ABSTRACT Background Canine atopic dermatitis (cAD) is a multifactorial, inherited skin disease, estimated to affect ≤ 15% of dogs. Studies of skin messenger mRNA in cAD currently use invasive methods, including blood sampling and biopsy collection, whilst advances in human atopic dermatitis study methodology have demonstrated reliable use of minimally ...
Xavier Langon   +5 more
wiley   +1 more source

Consideraciones éticas del rol de la enfermería en la coordinación de estudios clínicos

open access: yes, 2011
Introducción: A nivel mundial, el fenómeno de la investigación en el área de la salud está en ascenso, con la aparición de nuevos protocolos de ensayos clínicos la sociedad se está viendo obligada a garantizar la seguridad de sus pacientes participantes,
Miriam Jaramillo-Jiménez   +8 more
core   +1 more source

Nutritional Evaluation of Pediatric Patients with Sickle Cell Disease Treated with Hydroxyurea

open access: yesRevista Finlay, 2021
Background: clinical studies in patients with sickle cell disease have shown that the use of hydroxyurea is associated with a reduction in acute and chronic complications, including those related to the nutritional status of these patients. Objective: to
Belkis Lázara Rodríguez Jorge   +3 more
doaj   +2 more sources

ABCA12 Frameshift Deletion in Domestic Cats With Ichthyosis Fetalis

open access: yesVeterinary Dermatology, Volume 37, Issue 3, Page 365-374, June 2026.
ABSTRACT Background Ichthyosis fetalis (IF), also known as harlequin ichthyosis, is a rare and often fatal autosomal recessive congenital skin disorder. It is characterized by thickened, hard skin plaques and deep skin fissures that limit mobility and cause malformations of the eyes, lips and ears.
Jeanna M. Blake   +2 more
wiley   +1 more source

El employee engagement en monitores de estudios clínicos [PDF]

open access: yes, 2018
Fil: Restaino, Claudina M.. Universidad de San Andrés. Escuela de Negocios; Argentina.El presente trabajo aborda la cuestión del employee enagagement en monitores de estudios clínicos.
Restaino, Claudina M.
core  

Tolerability and Feasibility of Minimally Invasive Canine Skin Sampling: Excellent Tolerability Meets Transcriptomic Challenges

open access: yesVeterinary Dermatology, Volume 37, Issue 3, Page 375-385, June 2026.
ABSTRACT Background Advances in transcriptomics have driven the demand for minimally invasive, reproducible and high‐yield skin sampling methods, particularly for studying inflammatory skin diseases in companion animals. Hypothesis/Objectives We tested tolerability, feasibility and RNA quantity and quality of three minimally invasive skin sampling ...
Ina Herrmann   +2 more
wiley   +1 more source

Combined ACEI and ARB therapy and ICU mortality in critically ill COVID-19 patients: a retrospective cohort study

open access: yesFrontiers in Pharmacology
IntroductionThe clinical safety and potential benefits of renin–angiotensin–aldosterone system (RAAS) inhibitors in COVID-19 remain debated, particularly in critically ill populations.
Ivanny Marchant   +17 more
doaj   +1 more source

Ligand‐Based Pharmacophore Modeling and Structure‐Based Virtual Screening for Identifying Potential Therapeutic Agents Targeting the SARS‐CoV‐2 Spike Protein‐ACE2 Receptor Interaction

open access: yesChemMedChem, Volume 21, Issue 10, 27 May 2026.
A protocol guided by ligand‐based pharmacophore modeling and structure‐based virtual screening enabled the identification of 1H‐pyrazol‐5‐ol derivatives as novel inhibitors of the SARS‐CoV‐2 spike protein. The lead inhibitors, C‐3 and C‐4, could serve as templates for the design of potent antiviral agents targeting viral entry into host cells ...
Timoteo Delgado‐Maldonado   +5 more
wiley   +1 more source

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